Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Adrien H. Cerdan"'
Autor:
Sophie Shi, Solène N. Lefebvre, Laurie Peverini, Adrien H. Cerdan, Paula Milán Rodríguez, Marc Gielen, Jean-Pierre Changeux, Marco Cecchini, Pierre-Jean Corringer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Glycine receptors are channel receptors mediating signal transduction between neurons that transit between resting and open states upon neurotransmitter binding. Here, the authors illuminate a progressive transition of opening by combining voltage-cl
Externí odkaz:
https://doaj.org/article/2f309521f60544c4a944d621a652fe13
Autor:
Adrien H. Cerdan, Laurie Peverini, Jean-Pierre Changeux, Pierre-Jean Corringer, Marco Cecchini
Publikováno v:
Science Advances
Science Advances, 2022, 8 (41), pp.eadc9340. ⟨10.1126/sciadv.adc9340⟩
Science Advances, Vol. 8, No. 41
Science Advances, 2022, 8 (41), pp.eadc9340. ⟨10.1126/sciadv.adc9340⟩
Science Advances, Vol. 8, No. 41
In-house VMD scripts for counting ion permeation events via the lateral/apical pathways over time and counting the number of chloride ions in the vestibule are provided at the following links: https://doi.org/10.5281/zenodo.6935496 and https://doi.or
Autor:
Marco Cecchini, Adrien H. Cerdan
Publikováno v:
Structure
Structure, 2020, 28 (6), pp.690-693.e3. ⟨10.1016/j.str.2020.05.003⟩
Structure, Elsevier (Cell Press), 2020, 28, pp.690-693.e3. ⟨10.1016/j.str.2020.05.003⟩
Structure, 2020, 28 (6), pp.690-693.e3. ⟨10.1016/j.str.2020.05.003⟩
Structure, Elsevier (Cell Press), 2020, 28, pp.690-693.e3. ⟨10.1016/j.str.2020.05.003⟩
The glycine receptor (GlyR) is by far the best-characterized pentameric ligand-gated ion channel with several high-resolution structures from X-ray crystallography, cryo-EM and modeling. Nonetheless, the significance of the currently available open-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700b599a294a7708a48fd863ddcea615
https://doi.org/10.1101/2020.05.05.076802
https://doi.org/10.1101/2020.05.05.076802
Autor:
Jerome Becot, Nicolas Bosc, Adrien H. Cerdan, Mélaine A. Kuenemann, Marek Vavrusa, Olivier Sperandio
Publikováno v:
Journal of chemical information and modeling. 57(10)
Given the difficulties to identify chemical probes that can modulate protein–protein interactions (PPIs), actors in the field have started to agree on the necessity to use PPI-tailored screening chemical collections. However, which type of scaffold
Autor:
Thomas Grutter, Thierry Chataigneau, Alexandre Specht, Kate Dunning, Juline Beudez, Adrien H. Cerdan, Marco Cecchini, Laurie Peverini, Mahboubi Harkat, Nicolas Calimet, Adeline Martz
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (19), pp.E3786-E3795. ⟨10.1073/pnas.1701379114⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (19), pp.E3786-E3795. ⟨10.1073/pnas.1701379114⟩
International audience; Pore dilation is thought to be a hallmark of purinergic P2X receptors. The most commonly held view of this unusual process posits that under prolonged ATP exposure the ion pore expands in a striking manner from an initial smal
Publikováno v:
Scientific Reports
Protein-protein interactions (PPIs) play vital roles in life and provide new opportunities for therapeutic interventions. In this large data analysis, 3,300 inhibitors of PPIs (iPPIs) were compared to 17 reference datasets of collectively ~566,000 co
Autor:
Shi, Sophie, Lefebvre, Solène N., Peverini, Laurie, Cerdan, Adrien H., Milán Rodríguez, Paula, Gielen, Marc, Changeux, Jean-Pierre, Cecchini, Marco, Corringer, Pierre-Jean
Publikováno v:
Nature Communications; 2/13/2023, Issue 1, p1-13, 13p
Autor:
Cerdan, Adrien H, Sisquellas, Marion, Pereira, Gilberto, Gomes, Diego E Barreto, Changeux, Jean-Pierre, Cecchini, Marco
Publikováno v:
Bioinformatics; Jun2020, Vol. 36 Issue 11, p3379-3384, 6p
Autor:
Adrien Cerdan
Publikováno v:
Theoretical and/or physical chemistry. Université de Strasbourg, 2019. English. ⟨NNT : 2019STRAF006⟩
Adrien H. Cerdan
Adrien H. Cerdan
Signals within neurons are mostly transmitted through chemical synapses. Signal transduction arises from the binding of neurotransmitters to membrane receptors in order to open ion channels. The Glycine Receptor (GlyR) is an ionotropic receptor which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c2323095f888d34cd00c951914b16ba2
https://tel.archives-ouvertes.fr/tel-02338050
https://tel.archives-ouvertes.fr/tel-02338050
Autor:
Jie Zheng, Matthew C. Trudeau
The Textbook of Ion Channels is a set of three volumes that provides a wide-ranging refer- ence source on ion channels for students, instructors and researchers. Ion channels are membrane proteins that control the electrical properties of neurons and