Chromatin insulator factors involved in long-range DNA interactions and their role in the folding of the Drosophila genome.

Autor: Jutta Vogelmann, Antoine Le Gall, Stephanie Dejardin, Frederic Allemand, Adrien Gamot, Gilles Labesse, Olivier Cuvier, Nicolas Nègre, Martin Cohen-Gonsaud, Emmanuel Margeat, Marcelo Nöllmann

Publikováno v: PLoS Genetics, Vol 10, Iss 8, p e1004544 (2014)

Chromatin insulators are genetic elements implicated in the organization of chromatin and the regulation of transcription. In Drosophila, different insulator types were characterized by their locus-specific composition of insulator proteins and co-fa

Externí odkaz: https://doaj.org/article/daa8b11b0180433693cc1970280152b1

Chromatin Immunoprecipitation Indirect Peaks Highlight Long-Range Interactions of Insulator Proteins and Pol II Pausing

Autor: Jun Liang, Eldon Emberly, Sophie Queille, Olivier Bouchez, Pierre Lepetit, Keji Zhao, Laurent Lacroix, Olivier Cuvier, Gaël Micas, Franck Court, Serge Urbach, Pascal G.P. Martin, Suresh Cuddapah, Jutta Vogelmann, Magali Hennion, Marcelo Nollmann, Priscillia Lhoumaud, Adrien Gamot

Publikováno v: Molecular Cell
Molecular Cell, Elsevier, 2014, 53 (4), pp.672-681. ⟨10.1016/j.molcel.2013.12.029⟩
Molecular Cell, Cell Press, 2014, 53 (4), pp.672-681. ⟨10.1016/j.molcel.2013.12.029⟩

International audience; Eukaryotic chromosomes are partitioned into topologically associating domains (TADs) that are demarcated by distinct insulator-binding proteins (IBPs) in Drosophila. Whether IBPs regulate specific long-range contacts and how t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5c45a0b45d43e84d2f4dc5d0fa768e
https://doi.org/10.1016/j.molcel.2013.12.029

Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes

Autor: Monsef Benkirane, Slavik Koval, Gaël Micas, Nathalie Malirat, Raoul Raffel, Pascal G.P. Martin, Bernd Stadelmayer, Dany Severac, Hugues Parrinello, Bijan Sobhian, Olivier Cuvier, Adrien Gamot, Stéphanie Rialle

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2014, 5, pp.5531
Nature Communications, Nature Publishing Group, 2014, 5, pp.5531. ⟨10.1038/ncomms6531⟩
Nature Communications, 2014, 5, pp.5531. ⟨10.1038/ncomms6531⟩
Nature Communications (5), . (2014)

RNA polymerase II (RNAPII) pausing/termination shortly after initiation is a hallmark of gene regulation. Here, we show that negative elongation factor (NELF) interacts with Integrator complex subunits (INTScom), RNAPII and Spt5. The interaction betw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a59385fb97d405061b155ff80c08a0
https://hal.archives-ouvertes.fr/hal-01101245

Chromatin Insulator Factors Involved in Long-Range DNA Interactions and Their Role in the Folding of the Drosophila Genome.

Autor: Vogelmann, Jutta^1,2,3, Le Gall, Antoine^1,2,3, Dejardin, Stephanie^1,2,3, Allemand, Frederic^1,2,3, Gamot, Adrien⁴, Labesse, Gilles^1,2,3, Cuvier, Olivier⁴, Nègre, Nicolas⁵, Cohen-Gonsaud, Martin^1,2,3, Margeat, Emmanuel^1,2,3, Nöllmann, Marcelo^1,2,3 marcelo.nollmann@cbs.cnrs.fr

Publikováno v: PLoS Genetics. Aug2014, Vol. 10 Issue 8, p1-17. 17p.

Insulators recruit histone methyltransferase d Mes4 to regulate chromatin of flanking genes.

Autor: Lhoumaud, Priscillia, Hennion, Magali, Gamot, Adrien, Cuddapah, Suresh, Queille, Sophie, Liang, Jun, Micas, Gael, Morillon, Pauline, Urbach, Serge, Bouchez, Olivier, Severac, Dany, Emberly, Eldon, Zhao, Keji, Cuvier, Olivier

Publikováno v: EMBO Journal; 7/17/2014, Vol. 33 Issue 14, p1599-1613, 15p, 1 Diagram, 7 Graphs