Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Adrien Eberlin"'
Autor:
Jens Köhler, German Erlenkamp, Adrien Eberlin, Tobias Rumpf, Inna Slynko, Eric Metzger, Roland Schüle, Wolfgang Sippl, Manfred Jung
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34973 (2012)
BACKGROUND: Epigenetics is defined as heritable changes in gene expression that are not based on changes in the DNA sequence. Posttranslational modification of histone proteins is a major mechanism of epigenetic regulation. The kinase PRK1 (protein k
Externí odkaz:
https://doaj.org/article/aa12995d6bce4f1ca43c8fdd7b449c43
Autor:
Dominique Helmlinger, Sara Hardy, Gretta Abou-Sleymane, Adrien Eberlin, Aaron B Bowman, Anne Gansmüller, Serge Picaud, Huda Y Zoghbi, Yvon Trottier, Làszlò Tora, Didier Devys
Publikováno v:
PLoS Biology, Vol 4, Iss 3, p e67 (2006)
Spinocerebellar ataxia type 7 (SCA7) is one of several inherited neurodegenerative disorders caused by a polyglutamine (polyQ) expansion, but it is the only one in which the retina is affected. Increasing evidence suggests that transcriptional altera
Externí odkaz:
https://doaj.org/article/639ddf3c86644b5f81a8b449cf99f49c
Autor:
Adrien Eberlin, Jörn Dengjel, Anne Von Maessenhausen, Michael Schleicher, Philipp Metzger, Roland Schüle, Manfred Jung, Stefan Gerhardt, Joel McMillan, Ralf Flaig, Oliver Einsle, Dominica Willmann, Ignasi Forné, Daniel Wohlwend, Eric Metzger, Axel Imhof, Mark T. Bedford, Anne Kathrin Schott, Kerstin Petroll, Sven Perner, Alexsandra B. Espejo, Katrin M. Schüle, Sylvia Urban
Publikováno v:
Nature Structural & Molecular Biology. 23:132-139
Prostate cancer evolution is driven by a combination of epigenetic and genetic alterations such as coordinated chromosomal rearrangements, termed chromoplexy. TMPRSS2-ERG gene fusions found in human prostate tumors are a hallmark of chromoplexy. TMPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3894e756650aedbaaafe92bb9999904
https://doi.org/10.1038/nsmb.3153
https://doi.org/10.1038/nsmb.3153
Autor:
Adrien Eberlin, Nicolaus Friedrichs, Roland Schüle, Delphine Duteil, Judith M. Müller, Dominica Willmann, Dharmeshkumar Patel, Yves Tourrette
Publikováno v:
Development.
Nir/ Noc2l is an inhibitor of histone acetyl-transferases (INHAT). In addition to its function on histone acetylation, Nir binds to p53 and TAp63 to regulate their activity. Here, we show that epidermis-specific ablation of Nir impairs epidermal stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80804b5254d9eef2251c1f6b8b9c2023
https://doi.org/10.1242/dev.158543
https://doi.org/10.1242/dev.158543
Autor:
Elisabeth Maria Bissinger, V. Cura, Mark T. Bedford, Jean Cavarelli, Adrien Eberlin, Manfred Jung, Astrid Spannhoff, Eric Metzger, Wolfgang Sippl, Roland Schüle, Pierre Hassenboehler, Ralf Heinke
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:3717-3731
Arginine methylation is an epigenetic modification that receives increasing interest as it plays an important role in several diseases. This is especially true for hormone-dependent cancer, seeing that histone methylation by arginine methyltransferas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e3b105dae239befe05852df32b96f1
https://doi.org/10.1016/j.bmc.2011.02.032
https://doi.org/10.1016/j.bmc.2011.02.032
Autor:
Lourdes Ponce-Perez, Cédric Grauffel, Sarah Kimmins, Romain Lambrot, Laszlo Tora, Annick Dejaegere, Flavie Robert, Danièle Spehner, Maria-Elena Torres-Padilla, Roland H. Stote, Jean-Marie Wurtz, Adrien Eberlin, Mustapha Oulad-Abdelghani, Patrick Schultz
Publikováno v:
Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2008, 28 (5), pp.1739-54. ⟨10.1128/MCB.01180-07⟩
Molecular and Cellular Biology, American Society for Microbiology, 2008, 28 (5), pp.1739-54. ⟨10.1128/MCB.01180-07⟩
Condensation of chromatin, mediated in part by posttranslational modifications of histones, is essential for cell division during mitosis. Histone H3 tails are dimethylated on lysine (Kme2) and become phosphorylated on serine (Sp) residues during mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2287df8955a24eb2ac4a4f2e3a1ffa
https://doi.org/10.1128/mcb.01180-07
https://doi.org/10.1128/mcb.01180-07
Autor:
Tobias Rumpf, Wolfgang Sippl, German Erlenkamp, Jens Köhler, Eric Metzger, Roland Schüle, Inna Slynko, Adrien Eberlin, Manfred Jung
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34973 (2012)
PLoS ONE
PLoS ONE
BACKGROUND: Epigenetics is defined as heritable changes in gene expression that are not based on changes in the DNA sequence. Posttranslational modification of histone proteins is a major mechanism of epigenetic regulation. The kinase PRK1 (protein k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2868cc9798f1a26a1250c85c23d7347
http://europepmc.org/articles/PMC3332061?pdf=render
http://europepmc.org/articles/PMC3332061?pdf=render
Autor:
Anne Gansmüller, Dominique Helmlinger, Huda Y. Zoghbi, Aaron B. Bowman, Sara Hardy, Laszlo Tora, Didier Devys, Gretta Abou-Sleymane, Serge Picaud, Yvon Trottier, Adrien Eberlin
Publikováno v:
PLoS Biology
PLoS Biology, Public Library of Science, 2006, 4 (3), pp.e67. ⟨10.1371/journal.pbio.0040067⟩
PLoS Biology, Vol 4, Iss 3, p e70 (2006)
PLoS Biology, Public Library of Science, 2006, 4, pp.e67. ⟨10.1371/journal.pbio.0040067⟩
PLoS Biology, Vol 4, Iss 3, p e67 (2006)
PLoS Biology, 2006, 4 (3), pp.e67. ⟨10.1371/journal.pbio.0040067⟩
PLoS Biology, Public Library of Science, 2006, 4 (3), pp.e67. ⟨10.1371/journal.pbio.0040067⟩
PLoS Biology, Vol 4, Iss 3, p e70 (2006)
PLoS Biology, Public Library of Science, 2006, 4, pp.e67. ⟨10.1371/journal.pbio.0040067⟩
PLoS Biology, Vol 4, Iss 3, p e67 (2006)
PLoS Biology, 2006, 4 (3), pp.e67. ⟨10.1371/journal.pbio.0040067⟩
Spinocerebellar ataxia type 7 (SCA7) is one of several inherited neurodegenerative disorders caused by a polyglutamine (polyQ) expansion, but it is the only one in which the retina is affected. Increasing evidence suggests that transcriptional altera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a9bf8e1f3b08721ccdd15c2cece930
https://hal.archives-ouvertes.fr/hal-02371867
https://hal.archives-ouvertes.fr/hal-02371867
Publikováno v:
Biochemical Society Symposia
Biochemical Society Symposia, Portland Press, 2006, 73, pp.155-163. ⟨10.1042/bss0730155⟩
Biochemical Society Symposia, Portland Press, 2006, 73, pp.155-163. ⟨10.1042/bss0730155⟩
International audience; SCA7 (spinocerebellar ataxia type 7) is a neurodegenerative disorder caused by a CAG repeat expansion in the SCA7 gene that leads to elongation of a polyglutamine tract in ataxin-7, a protein of unknown function. Sgf73, a puta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990d559b1272fdda490918a503bb0ccb
https://hal.archives-ouvertes.fr/hal-02990344
https://hal.archives-ouvertes.fr/hal-02990344