Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing

Autor: Aymeric Silvin, Pierre-Emmanuel Joubert, Jacob-Sebastian Seeler, Ido Amit, Joao G. Magalhaes, Nicolas Manel, Jack-Christophe Cossec, Anne Dejean, Adrien Decque, Olivier Joffre, Ronnie Blecher-Gonen, Sebastian Amigorena, Pierre Lapaquette, Matthew L. Albert

Publikováno v: Nature Immunology
Nature Immunology, 2016, 17 (2), pp.140-149. ⟨10.1038/ni.3342⟩
Nature Immunology, Nature Publishing Group, 2016, 17 (2), pp.140-149. ⟨10.1038/ni.3342⟩

International audience; Innate sensing of pathogens initiates inflammatory cytokine responses that need to be tightly controlled. We found here that after engagement of Toll-like receptors (TLRs) in myeloid cells, deficient sumoylation caused increas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082a2423966ca06422f4633b1d591ca6
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