Hybrid Mineral/Organic Material Induces Bone Bridging and Bone Volume Augmentation in Rat Calvarial Critical Size Defects

Autor: Marie Dubus, Loïc Scomazzon, Charlotte Ledouble, Julien Braux, Abdelilah Beljebbar, Laurence Van Gulick, Adrien Baldit, Caroline Gorin, Halima Alem, Nicole Bouland, Marissa Britton, Jessica Schiavi, Ted J. Vaughan, Cédric Mauprivez, Halima Kerdjoudj

Publikováno v: Cells, Vol 11, Iss 18, p 2865 (2022)

In craniofacial bone defects, the promotion of bone volume augmentation remains a challenge. Finding strategies for bone regeneration such as combining resorbable minerals with organic polymers would contribute to solving the bone volume roadblock. H

Externí odkaz: https://doaj.org/article/215830ba733647a8b0b68527b4ece904

A preliminary study exploring the mechanical properties of normal and Mgp-deficient mouse femurs during early growth

Autor: Cédric Laurent, Alexandre Marano, Adrien Baldit, Maude Ferrari, Jean-Christophe Perrin, Olivier Perroud, Arnaud Bianchi, Hervé Kempf

Publikováno v: Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 236:1106-1117

Matrix Gla protein (MGP) is mostly known to be a calcification inhibitor, as its absence leads to ectopic calcification of different tissues such as cartilage or arteries. MGP deficiency also leads to low bone mass and delayed bone growth. In the pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23196c7dfbf1556eb9fd5029a33129e
https://doi.org/10.1177/09544119221109019

Antibacterial and Immunomodulatory Properties of Acellular Wharton’s Jelly Matrix

Autor: Kerdjoudj, Marie Dubus, Loïc Scomazzon, Julie Chevrier, Charlotte Ledouble, Adrien Baldit, Julien Braux, Florelle Gindraux, Camille Boulagnon, Sandra Audonnet, Marius Colin, Hassan Rammal, Cédric Mauprivez, Halima

Publikováno v: Biomedicines; Volume 10; Issue 2; Pages: 227

Of all biologic matrices, decellularized tissues have emerged as a promising tool in the field of regenerative medicine. Few empirical clinical studies have shown that Wharton’s jelly (WJ) of the human umbilical cord promotes wound closure and redu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::672ba875978864cb11c0ebb354177410

How do the effective bone properties evolve during normal and pathological calcification?

Autor: Jean-Christophe Perrin, Arnaud Bianchi, Alexandre Marano, Hervé Kempf, Cédric Laurent, Adrien Baldit, Maude Ferrari

Publikováno v: Computer Methods in Biomechanics and Biomedical Engineering
Computer Methods in Biomechanics and Biomedical Engineering, Taylor & Francis, 2020, 23 (sup1), pp.S166-S168. ⟨10.1080/10255842.2020.1813417⟩

International audience; Numerous diseases are associated with (or due to) a pathologic calcification of the skeleton. It may involve a defect in calcification (as in bone in osteoporotic patients) or on the contrary, an excess of calcification, or ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5a53cab66b2f0eb80b34be54536b7d
https://hal.archives-ouvertes.fr/hal-03145718

Collagen Gel Cell Encapsulation to Study Mechanotransduction

Autor: Adrien Baldit, Cecile M. Perrault, Damien Lacroix, Maryam Shariatzadeh

Publikováno v: Multiscale Mechanobiology in Tissue Engineering
Multiscale Mechanobiology in Tissue Engineering, pp.105-125, 2019, ⟨10.1007/978-981-10-8075-3_6⟩
Multiscale Mechanobiology in Tissue Engineering, pp.105-125, 2019, 978-981-10-8074-6. ⟨10.1007/978-981-10-8075-3_6⟩
Frontiers of Biomechanics ISBN: 9789811080746

International audience; Mechanical forces and 3D topological environment can be used to control differentiation of mesenchymal stem cells (MSCs). However, the effects of physical and mechanical cues of the microenvironment on MSC fate determination h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cc483393720f25d5d278b8b91d7ac74
https://hal.univ-lorraine.fr/hal-02063161