Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Adrianos, Nezos"'
Autor:
George E. Fragoulis, Panagiotis A. Ntouros, Adrianos Nezos, Nikolaos I. Vlachogiannis, Iain B. McInnes, Maria G. Tektonidou, Charalampos Skarlis, Vassilis L. Souliotis, Clio P. Mavragani, Petros P. Sfikakis
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectivesThe abnormal DNA damage response is associated with upregulation of the type-1 interferon (IFN-I) pathway in certain rheumatic diseases. We investigated whether such aberrant mechanisms operate in psoriatic arthritis (PsA).MethodsDNA damage
Externí odkaz:
https://doaj.org/article/621e1123c1474172aaab94f3a9866808
Autor:
Athanasios Armakolas, Vasiliki Dimopoulou, Adrianos Nezos, George Stamatakis, Martina Samiotaki, George Panayotou, Maria Tampaki, Martha Stathaki, Spyridon Dourakis, John Koskinas
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 10, Pp 4714-4734 (2022)
Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers. Early detection/diagnosis is vital for the prognosis of HCC, whereas diagnosis at late stages is associated with very low survival rate. Early diagnosis is based on 6-
Externí odkaz:
https://doaj.org/article/a9245a65e74c4870be8c3f5c85c1911e
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract We aimed to explore whether the rs2073618 variant (G1181C) of the osteoprotegerin (OPG) gene and the methylenetetrahydrofolate reductase (MTHFR) rs1801131 (A1298AC) and rs1801133 (C677T) gene polymorphisms contribute to rheumatoid arthritis
Externí odkaz:
https://doaj.org/article/dc33e19cbf504b81942afd993b675dd3
Autor:
Dimitris K. Karathanasis, Anna Rapti, Adrianos Nezos, Charalampos Skarlis, Constantinos Kilidireas, Clio P. Mavragani, Maria Eleftheria Evangelopoulos
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: While multiple sclerosis (MS) is considered the cornerstone of autoimmune demyelinating CNS disorders, systemic autoimmune diseases (SADs) are important MS mimickers. We sought to explore whether distinct clinical, laboratory, and imaging
Externí odkaz:
https://doaj.org/article/d6e02b4fde52450282765f3ed15c8a90
Lipoprotein-Associated Phospholipase A2: A Novel Contributor in Sjögren’s Syndrome-Related Lymphoma?
Autor:
Adrianos Nezos, Charalampos Skarlis, Anna Psarrou, Konstantinos Markakis, Panagiotis Garantziotis, Asimina Papanikolaou, Fotini Gravani, Michael Voulgarelis, Athanasios G. Tzioufas, Michael Koutsilieris, Haralampos M. Moutsopoulos, Eleni Kotsifaki, Clio P. Mavragani
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundB-cell non-Hodgkin’s lymphoma (B-NHL) is one of the major complications of primary Sjögren’s syndrome (SS). Chronic inflammation and macrophages in SS minor salivary glands have been previously suggested as significant predictors for l
Externí odkaz:
https://doaj.org/article/a76ab592f8a348f4aaddce5cf22d429b
Autor:
Nikolaos I. Vlachogiannis, Maria Pappa, Panagiotis A. Ntouros, Adrianos Nezos, Clio P. Mavragani, Vassilis L. Souliotis, Petros P. Sfikakis
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Increased endogenous DNA damage and type I interferon pathway activation have been implicated in systemic sclerosis (SSc) pathogenesis. Because experimental evidence suggests an interplay between DNA damage response/repair (DDR/R) and immune response
Externí odkaz:
https://doaj.org/article/f44649c13ecd471a99f4634e7ca69e14
Autor:
Sofia Fragkioudaki, Adrianos Nezos, Vassilis L. Souliotis, Ilenia Chatziandreou, Angelica A. Saetta, Nikolaos Drakoulis, Athanasios G. Tzioufas, Michael Voulgarelis, Petros P. Sfikakis, Michael Koutsilieris, Mary K. Crow, Haralampos M. Moutsopoulos, Clio P. Mavragani
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Primary Sjogren’s syndrome (pSS) confers increased risk for non-Hodgkin lymphoma (NHL) development. Two common polymorphisms, the c. 677C > T and c. 1298A > C, of the methylene-tetrahydrofolate reductase (MTHFR) gene, an enzyme essential i
Externí odkaz:
https://doaj.org/article/3da35a06e8ad43e58ea639c207651de5
Autor:
Nikolaos Kintrilis, Fotini Gravani, Anna Rapti, Myrto Papaioannou, Christina-Maria Flessa, Adrianos Nezos, Eleni Antypa, Ioanna Papadaki, Τheofanis Karageorgas, Haralampos M Moutsopoulos, Clio P Mavragani
Publikováno v:
Rheumatology. 62:958-968
Objectives RA and primary SS carry increased atherosclerotic risk, while B-cell activating factor holds a vital role in disease pathogenesis and atherosclerosis. We aimed to compare subclinical atherosclerosis profiles between the two clinical entiti
Autor:
Adrianos Nezos, Eliona Gkioka, Michael Koutsilieris, Michael Voulgarelis, Athanasios G. Tzioufas, Clio P. Mavragani
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Tumor necrosis factor, alpha-induced protein 3 (TNFAIP3) gene encodes the A20 protein, an important negative feedback regulator of the nuclear factor kappa-light-chain-enhancer of activated B cell (NF-κB) pathway. A coding TNFAIP3 variant, namely rs
Externí odkaz:
https://doaj.org/article/736dc0524f5f455abf36e51d7aeb4d2a
Publikováno v:
Journal of clinical medicine. 11(5)
Milk Fat Globule Epidermal Growth Factor 8 (MFGE8) deficiency and gene polymorphisms have been previously linked to systemic lupus erythematosus (SLE)-like and SLE development. Our aim was to explore whether four MFGE8 variants and MFGE8 serum levels