Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Adriano O Henriques"'
Autor:
Eleonora Marini, Carmen Olivença, Sara Ramalhete, Andrea Martinez Aguirre, Patrick Ingle, Manuel N Melo, Wilson Antunes, Nigel P Minton, Guillem Hernandez, Tiago N Cordeiro, Joseph A Sorg, Mónica Serrano, Adriano O Henriques
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011741 (2023)
A genomic signature for endosporulation includes a gene coding for a protease, YabG, which in the model organism Bacillus subtilis is involved in assembly of the spore coat. We show that in the human pathogen Clostridioidesm difficile, YabG is critic
Externí odkaz:
https://doaj.org/article/7c0c299799724715ab006823f9bfa0a6
Autor:
Catarina G Fernandes, Diogo Martins, Guillem Hernandez, Ana L Sousa, Carolina Freitas, Erin M Tranfield, Tiago N Cordeiro, Mónica Serrano, Charles P Moran, Adriano O Henriques
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1007912 (2019)
In many cases protein assemblies are stabilized by covalent bonds, one example of which is the formation of intra- or intermolecular ε-(γ-glutamyl)lysil cross-links catalyzed by transglutaminases (TGases). Because of the potential for unwanted cros
Externí odkaz:
https://doaj.org/article/b268ee7501934ffc81cfc8d1b57140c4
Autor:
Carolina P. Cassona, Sara Ramalhete, Khira Amara, Thomas Candela, Imad Kansau, Cécile Denève-Larrazet, Claire Janoir-Jouveshomme, Luís Jaime Mota, Bruno Dupuy, Mónica Serrano, Adriano O. Henriques
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Clostridioides difficile causes a wide range of intestinal diseases through the action of two main cytotoxins, TcdA and TcdB. Ingested spores germinate in the intestine establishing a population of cells that produce toxins and spores. The p
Externí odkaz:
https://doaj.org/article/500b2926323d4461b78669511dd7fbed
Autor:
Mónica Serrano, Nicolas Kint, Fátima C Pereira, Laure Saujet, Pierre Boudry, Bruno Dupuy, Adriano O Henriques, Isabelle Martin-Verstraete
Publikováno v:
PLoS Genetics, Vol 12, Iss 9, p e1006312 (2016)
The strict anaerobe Clostridium difficile is the most common cause of nosocomial diarrhea, and the oxygen-resistant spores that it forms have a central role in the infectious cycle. The late stages of sporulation require the mother cell regulatory pr
Externí odkaz:
https://doaj.org/article/5b3fb6061202449fa108964329eda69f
Autor:
Mónica Serrano, JinXin Gao, João Bota, Ashley R Bate, Jeffrey Meisner, Patrick Eichenberger, Charles P Moran, Adriano O Henriques
Publikováno v:
PLoS Genetics, Vol 11, Iss 4, p e1005104 (2015)
Gene expression during spore development in Bacillus subtilis is controlled by cell type-specific RNA polymerase sigma factors. σFand σE control early stages of development in the forespore and the mother cell, respectively. When, at an intermediat
Externí odkaz:
https://doaj.org/article/0ffd8646a6284c34977283ecea34f699
Autor:
Luísa Côrte, Filipa Valente, Mónica Serrano, Cláudio M Gomes, Charles P Moran, Adriano O Henriques
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e99811 (2014)
During sporulation in Bacillus subtilis, the onset of activity of the late forespore-specific sigma factor σG coincides with completion of forespore engulfment by the mother cell. At this stage, the forespore becomes a free protoplast, surrounded by
Externí odkaz:
https://doaj.org/article/4f64dd7c90f6455b84174b5ab57d99ce
Autor:
Laure Saujet, Fátima C Pereira, Monica Serrano, Olga Soutourina, Marc Monot, Pavel V Shelyakin, Mikhail S Gelfand, Bruno Dupuy, Adriano O Henriques, Isabelle Martin-Verstraete
Publikováno v:
PLoS Genetics, Vol 9, Iss 10, p e1003756 (2013)
Clostridium difficile, a Gram positive, anaerobic, spore-forming bacterium is an emergent pathogen and the most common cause of nosocomial diarrhea. Although transmission of C. difficile is mediated by contamination of the gut by spores, the regulato
Externí odkaz:
https://doaj.org/article/a9ddb3e12cd645b5a819792673f60272
Autor:
Fátima C Pereira, Laure Saujet, Ana R Tomé, Mónica Serrano, Marc Monot, Evelyne Couture-Tosi, Isabelle Martin-Verstraete, Bruno Dupuy, Adriano O Henriques
Publikováno v:
PLoS Genetics, Vol 9, Iss 10, p e1003782 (2013)
Endosporulation is an ancient bacterial developmental program that culminates with the differentiation of a highly resistant endospore. In the model organism Bacillus subtilis, gene expression in the forespore and in the mother cell, the two cells th
Externí odkaz:
https://doaj.org/article/fd53637b9d944e4da686ee158a6e84e1
Autor:
Mónica Serrano, Gonçalo Real, Joana Santos, Jorge Carneiro, Charles P Moran, Adriano O Henriques
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002220 (2011)
Two highly similar RNA polymerase sigma subunits, σ(F) and σ(G), govern the early and late phases of forespore-specific gene expression during spore differentiation in Bacillus subtilis. σ(F) drives synthesis of σ(G) but the latter only becomes a
Externí odkaz:
https://doaj.org/article/9ee860f20b2f4b1fa7b28b2daa37315f
Autor:
Thierry Doan, Cecile Morlot, Jeffrey Meisner, Monica Serrano, Adriano O Henriques, Charles P Moran, David Z Rudner
Publikováno v:
PLoS Genetics, Vol 5, Iss 7, p e1000566 (2009)
Sporulation in Bacillus subtilis involves two cells that follow separate but coordinately regulated developmental programs. Late in sporulation, the developing spore (the forespore) resides within a mother cell. The regulation of the forespore transc
Externí odkaz:
https://doaj.org/article/474506d4274d456ba755a0e5b7f842e1