Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Adriano Maida"'
Autor:
Gretchen Wolff, Minako Sakurai, Amit Mhamane, Maria Troullinaki, Adriano Maida, Ioannis K. Deligiannis, Kelvin Yin, Peter Weber, Jakob Morgenstern, Annika Wieder, Yun Kwon, Revathi Sekar, Anja Zeigerer, Michael Roden, Matthias Blüher, Nadine Volk, Tanja Poth, Thilo Hackert, Lena Wiedmann, Francesca De Angelis Rigotti, Juan Rodriguez-Vita, Andreas Fischer, Rajesh Mukthavaram, Pattraranee Limphong, Kiyoshi Tachikawa, Priya Karmali, Joseph Payne, Padmanabh Chivukula, Bilgen Ekim-Üstünel, Celia P. Martinez-Jimenez, Julia Szendrödi, Peter Nawroth, Stephan Herzig
Publikováno v:
Molecular Metabolism, Vol 60, Iss , Pp 101487- (2022)
Objective: Fibrotic organ responses have recently been identified as long-term complications in diabetes. Indeed, insulin resistance and aberrant hepatic lipid accumulation represent driving features of progressive non-alcoholic fatty liver disease (
Externí odkaz:
https://doaj.org/article/7ffd9988b903457a8a6a90287967ed13
Autor:
Jürgen G. Okun, Sean Conway, Kathrin V. Schmidt, Jonas Schumacher, Xiaoyue Wang, Roldan de Guia, Annika Zota, Johanna Klement, Oksana Seibert, Achim Peters, Adriano Maida, Stephan Herzig, Adam J. Rose
Publikováno v:
Molecular Metabolism, Vol 41, Iss , Pp 101068- (2020)
Externí odkaz:
https://doaj.org/article/a2cf1663ae7346c6918f207c081fa7c3
Autor:
Adriano Maida, Jessica S.K. Chan, Kim A. Sjøberg, Annika Zota, Dieter Schmoll, Bente Kiens, Stephan Herzig, Adam J. Rose
Publikováno v:
Molecular Metabolism, Vol 6, Iss 8, Pp 873-881 (2017)
Objective: Dietary protein dilution (PD) has been associated with metabolic advantages such as improved glucose homeostasis and increased energy expenditure. This phenotype involves liver-induced release of FGF21 in response to amino acid insufficien
Externí odkaz:
https://doaj.org/article/f6363aa7cf6240e9b95f8b776bf5df2e
Autor:
Bilgen Ekim Üstünel, Kilian Friedrich, Adriano Maida, Xiaoyue Wang, Anja Krones-Herzig, Oksana Seibert, Anke Sommerfeld, Allan Jones, Tjeerd P. Sijmonsma, Carsten Sticht, Norbert Gretz, Thomas Fleming, Peter P. Nawroth, Wolfgang Stremmel, Adam J. Rose, Mauricio Berriel-Diaz, Matthias Blüher, Stephan Herzig
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
TSC22D4 regulates hepatic lipoprotein production, but has so far mainly been studied in the context of cancer cachexia. Here, the authors show TSC22D4 inhibition improves insulin sensitivity in several mouse models of diabetes, which they attribute a
Externí odkaz:
https://doaj.org/article/6fbad84b0b124d8487619a25d73053a2
Autor:
Jessica Fuhrmeister, Annika Zota, Tjeerd P Sijmonsma, Oksana Seibert, Şahika Cıngır, Kathrin Schmidt, Nicola Vallon, Roldan M de Guia, Katharina Niopek, Mauricio Berriel Diaz, Adriano Maida, Matthias Blüher, Jürgen G Okun, Stephan Herzig, Adam J Rose
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 6, Pp 654-669 (2016)
Abstract Recent studies have demonstrated that repeated short‐term nutrient withdrawal (i.e. fasting) has pleiotropic actions to promote organismal health and longevity. Despite this, the molecular physiological mechanisms by which fasting is prote
Externí odkaz:
https://doaj.org/article/01d8e283e740411db13c507463c1aa34
Autor:
Jürgen G. Okun, Sean Conway, Kathrin V. Schmidt, Jonas Schumacher, Xiaoyue Wang, Roldan de Guia, Annika Zota, Johanna Klement, Oksana Seibert, Achim Peters, Adriano Maida, Stephan Herzig, Adam J. Rose
Publikováno v:
Molecular Metabolism, Vol 4, Iss 10, Pp 732-740 (2015)
Objective: One of the major side effects of glucocorticoid (GC) treatment is lean tissue wasting, indicating a prominent role in systemic amino acid metabolism. In order to uncover a novel aspect of GCs and their intracellular-receptor, the glucocort
Externí odkaz:
https://doaj.org/article/4a99fcb494a54ed0811d5b0e245017b1
Autor:
Ana Jimena Alfaro Nunez, Claudia Dittner, Janina Becker, Anne Loft, Amit Mhamane, Adriano Maida, Anastasia Georgiadi, Phivos Tsokanos, Katarina Klepac, Eveline Molocea, Rabih Merahbi, Karsten Motzler, Julia Geppert, Rhoda Anane Karikari, Julia Szendrödi, Annette Feuchtinger, Susanna Hofmann, Frauke Melchior, Stephan Herzig
The liver is the major metabolic hub, ensuring appropriate nutrient supply during fasting and feeding. In obesity, accumulation of excess nutrients hampers proper liver function and is linked to non-alcoholic fatty liver disease. Understanding the si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4307bd65cd9049ebf78470aaf32f555
https://doi.org/10.1101/2022.08.17.504229
https://doi.org/10.1101/2022.08.17.504229
Autor:
Anne Loft, Søren Fisker Schmidt, Giorgio Caratti, Ulrich Stifel, Jesper Havelund, Revathi Sekar, Yun Kwon, Alba Sulaj, Kan Kau Chow, Ana Jimena Alfaro, Thomas Schwarzmayr, Nikolaj Rittig, Mads Svart, Foivos-Filippos Tsokanos, Adriano Maida, Andreas Blutke, Annette Feuchtinger, Niels Møller, Matthias Blüher, Peter Nawroth, Julia Szendrödi, Nils J. Færgeman, Anja Zeigerer, Jan Tuckermann, Stephan Herzig
Publikováno v:
Loft, A, Schmidt, S F, Caratti, G, Stifel, U, Havelund, J, Sekar, R, Kwon, Y, Sulaj, A, Chow, K K, Alfaro, A J, Schwarzmayr, T, Rittig, N, Svart, M, Tsokanos, F-F, Maida, A, Blutke, A, Feuchtinger, A, Møller, N, Blüher, M, Nawroth, P, Szendrödi, J, Færgeman, N J, Zeigerer, A, Tuckermann, J & Herzig, S 2022, ' A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis ', Cell Metabolism, vol. 34, no. 3, pp. 473-486.e9 . https://doi.org/10.1016/j.cmet.2022.01.004
Cell Metab. 34, 473-486.e9 (2022)
Cell Metab. 34, 473-486.e9 (2022)
Fasting metabolism and immunity are tightly linked; however, it is largely unknown how immune cells contribute to metabolic homeostasis during fasting in healthy subjects. Here, we combined cell-type-resolved genomics and computational approaches to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1176debd7a818f3d89034abe8a0ebbf9
https://portal.findresearcher.sdu.dk/da/publications/02b4d631-bd41-4587-bffa-5deb4c5f7d57
https://portal.findresearcher.sdu.dk/da/publications/02b4d631-bd41-4587-bffa-5deb4c5f7d57
Autor:
Sevgican Demir, Gretchen Wolff, Annika Wieder, Adriano Maida, Lea Bühler, Maik Brune, Oksana Hautzinger, Annette Feuchtinger, Tanja Poth, Julia Szendroedi, Stephan Herzig, Bilgen Ekim Üstünel
Publikováno v:
Sci. Adv. 8:eabo5555 (2022)
Maladaptive insulin signaling is a key feature in the pathogenesis of severe metabolic disorders, including obesity and diabetes. Enhancing insulin sensitivity represents a major goal in the treatment of patients affected by diabetes. Here, we identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de2239d56c48a7c0876ed898d74e055
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66470
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=66470
Autor:
Eikan Mishima, Junya Ito, Zijun Wu, Toshitaka Nakamura, Adam Wahida, Sebastian Doll, Wulf Tonnus, Palina Nepachalovich, Elke Eggenhofer, Maceler Aldrovandi, Bernhard Henkelmann, Ken-ichi Yamada, Jonas Wanninger, Omkar Zilka, Emiko Sato, Regina Feederle, Daniela Hass, Adriano Maida, André Santos Dias Mourão, Andreas Linkermann, Edward K. Geissler, Kiyotaka Nakagawa, Takaaki Abe, Maria Fedorova, Bettina Proneth, Derek A. Pratt, Marcus Conrad
Publikováno v:
Nature 608, 778–783 (2022)
Nature 608, 778-783 (2022)
Nature 608, 778-783 (2022)
Ferroptosis, a non-apoptotic form of cell death marked by iron-dependent lipid peroxidation1, has a key role in organ injury, degenerative disease and vulnerability of therapy-resistant cancers2. Although substantial progress has been made in underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8809f78215f764eae9c43453741d95a6