Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Adriano Henney"'
Autor:
Hannah Coaker, Adriano Henney
Publikováno v:
Future Medicinal Chemistry. 6:1735-1740
Adriano Henney speaks to Hannah Coaker, Commissioning Editor. After achieving a PhD in medicine and spending many years in academic research in the field of cardiovascular disease, Adriano Henney was recruited by Zeneca Pharmaceuticals from a British
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f70b09838b75e3d10c149ce17391ce05
https://doi.org/10.4155/fmc.14.127
https://doi.org/10.4155/fmc.14.127
Autor:
Liang Zhao, Yeyejide Adeleye, Rob Stierum, Richard J. Brennan, Mounir Bouhifd, Lena Smirnova, Stefano Monti, Akhilesh Pandey, Ben Gordon, Justin Lamb, Kevin M. Crofton, Avi Ma'ayan, Clemens Wittwehr, Melvin E. Andersen, Catherine Willett, Suzanne Fitzpatrick, Kevin W. Gaido, Michael Rosenberg, Andre Kleensang, Minoru Kanehisa, Alexandra Maertens, Michael F. Ochs, Mary McBride, Robin Haw, Roded Sharan, Albert J. Fornace, Kirk Arvidson, Stuart Tugendreich, David Gerhold, Helena T. Hogberg, Thomas Hartung, Jianguo Xia, Thomas Luechtefeld, Paul L. Carmichael, Geoffrey W. Patton, Scott S. Auerbach, Adriano Henney
Publikováno v:
ALTEX. 31:53-61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5342dc5090fa5d17fc353b6e9a9c30c8
https://doi.org/10.14573/altex.1309261
https://doi.org/10.14573/altex.1309261
Publikováno v:
Wiley Interdisciplinary Reviews: Systems Biology and Medicine
Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2013, 4 (3), pp.221-35. ⟨10.1002/wsbm.1158⟩
Wiley Interdisciplinary Reviews: Systems Biology and Medicine, Wiley, 2013, 4 (3), pp.221-35. ⟨10.1002/wsbm.1158⟩
Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2013, 4 (3), pp.221-35. ⟨10.1002/wsbm.1158⟩
Wiley Interdisciplinary Reviews: Systems Biology and Medicine, Wiley, 2013, 4 (3), pp.221-35. ⟨10.1002/wsbm.1158⟩
International audience; The liver is the central metabolic organ in human physiology, with functions that are fundamentally important to the detoxification of xenobiotics (drugs), the maintenance of homeostasis of numerous blood metabolites, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409f8a88058eaed18138caff65ec3147
https://doi.org/10.1002/wsbm.1158
https://doi.org/10.1002/wsbm.1158
Publikováno v:
BioEssays. 32:1099-1104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2b7a05f5c4022fc7934b67cebba55c1
https://doi.org/10.1002/bies.201000109
https://doi.org/10.1002/bies.201000109
The term ‘in silico clinical trials indicates the use of individualised computer simulation in the development or regulatory evaluation of a medicinal product, medical device, or medical intervention. This review article summarises the research and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6ed45c103ed62a10ca4ece3bad8e9f
Publikováno v:
Progress in biophysics and molecular biology. 117(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95ef56a4c31b7d653e337fac99e7ee7
https://pubmed.ncbi.nlm.nih.gov/25783046
https://pubmed.ncbi.nlm.nih.gov/25783046
Autor:
Adriano Henney
Publikováno v:
Expert Opinion on Drug Discovery. 1:653-661
The rapid expansion of biomedical information following the mapping of the human genome has contributed to significant advances in acquiring a highly detailed picture of disease mechanisms at the molecular level. This revolution in biomedical science
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3210be0e25e0124acacb80384221431e
https://doi.org/10.1517/17460441.1.7.653
https://doi.org/10.1517/17460441.1.7.653
Publikováno v:
Progress in Biophysics and Molecular Biology
Progress in Biophysics and Molecular Biology, Elsevier, 2015, 117 (1), pp.78-86. ⟨10.1016/j.pbiomolbio.2014.11.005⟩
Progress in Biophysics and Molecular Biology, 2015, 117 (1), pp.78-86. ⟨10.1016/j.pbiomolbio.2014.11.005⟩
Progress in Biophysics and Molecular Biology, Elsevier, 2015, 117 (1), pp.78-86. ⟨10.1016/j.pbiomolbio.2014.11.005⟩
Progress in Biophysics and Molecular Biology, 2015, 117 (1), pp.78-86. ⟨10.1016/j.pbiomolbio.2014.11.005⟩
International audience; Biological responses are determined by information processing at multiple and highly interconnected scales. Within a tissue the individual cells respond to extracellular stimuli by regulating intracellular signaling pathways t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ca6a236da10e910f67a5a8250dd13b
https://hal.inria.fr/hal-01257160
https://hal.inria.fr/hal-01257160
Autor:
Adriano Henney, Claire A. Minshull, Derek Barratt, Siân Rowsell, David Waterson, Richard A. Pauptit, Holly Jepson, Paul Hawtin, Anthony M. Slater, William L. McPheat, S.M. Brockbank
Publikováno v:
Journal of Molecular Biology. 319:173-181
Matrix metalloproteinases (MMPs) and their inhibitors are important in connective tissue re-modelling in diseases of the cardiovascular system, such as atherosclerosis. Various members of the MMP family have been shown to be expressed in atherosclero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26656f3d4802a189dcdff04def3f2c2a
https://doi.org/10.1016/s0022-2836(02)00262-0
https://doi.org/10.1016/s0022-2836(02)00262-0
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
The liver is the central detoxifying organ, continuously removing xenobiotics from the vascular system. Given its role in drug metabolism, a functional understanding of liver physiology is crucial to optimizing drug efficacy and patient safety. The V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f26e26ebf99932b38dcf154d500475a
https://pubmed.ncbi.nlm.nih.gov/25076067
https://pubmed.ncbi.nlm.nih.gov/25076067