Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Adriano G Rossi"'
Autor:
Callum AH Docherty, Anuruddika J Fernando, Sarah Rosli, Maggie Lam, Roland E Dolle, Manuel A Navia, Ronald Farquhar, Danny La France, Michelle D Tate, Christopher K Murphy, Adriano G Rossi, Ashley Mansell
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 6, Pp n/a-n/a (2023)
Abstract Objectives Inflammasomes induce maturation of the inflammatory cytokines IL‐1β and IL‐18, whose activity is associated with the pathophysiology of a wide range of infectious and inflammatory diseases. As validated therapeutic targets fo
Externí odkaz:
https://doaj.org/article/f402fa42dc57419ea86338a42ffe4836
Autor:
Natalie Pattison, Richard J Mellanby, Ian Handel, Timothy S Walsh, Marlies Ostermann, Mark Lyttle, Adriano G Rossi, David M Griffith, Manu Shankar-Hari, Carlo Palmieri, Lance Turtle, Alexander J Mentzer, Lewis W S Fisher, James Scott-Brown, Danai Papakonstantinou, Effrossyni Gkrania-Klotsas, Kerri Devine, Daniel G Wootton, Padmasayee Papineni, Benjamin W A Catterall, Lara Lavelle-Langham, Emily Cass, Alejandra Doce Carracedo, Lisa Flaherty, Nicole Maziere, Hannah Massey, Anthony Holmes, Nicola Carlucci, Matthew K O'Shea, Emma A Hurst, Natalie Z Homer, Scott G Denham, Paul A Holloway, Romit J Samanta, Thushan de Silva, A A Roger Thompson, Ruth Lyons, Murray Wham, Sara Clohisey, Sara McDonald, Seán Keating, Lorna Finch, Lee Murphy, Nicola Wrobel, Sarah McCafferty, Kirstie Morrice, Alan MacLean, Erin L Aldera, Sneha Basude, Steven Laird, Antonia Ying Wai Ho
Publikováno v:
BMJ Open, Vol 11, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/ad056de08ff94ae997371b1daab2d244
Autor:
Brian J McHugh, Rongling Wang, Hsin-Ni Li, Paula E Beaumont, Rebekah Kells, Holly Stevens, Lisa Young, Adriano G Rossi, Robert D Gray, Julia R Dorin, Emily L Gwyer Findlay, David Brough, Donald J Davidson
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007694 (2019)
Pulmonary infections are a major global cause of morbidity, exacerbated by an increasing threat from antibiotic-resistant pathogens. In this context, therapeutic interventions aimed at protectively modulating host responses, to enhance defence agains
Externí odkaz:
https://doaj.org/article/b0ced40c6ffd4268b60634efa7b7782e
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 100, Pp 67-71 (2005)
The ubiquitous free radical, nitric oxide (NO), plays an important role in many biological processes including the regulation of the inflammatory response. Alterations in NO synthesis by endogenous systems likely influence inflammatory processes occu
Externí odkaz:
https://doaj.org/article/407086dbd5f14864b3791ca7d15a15da
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
Due to the key role of the lung in efficient transfer of oxygen in exchange for carbon dioxide, a controlled inflammatory response is essential for restoration of tissue homeostasis following airway exposure to bacterial pathogens or environmental to
Externí odkaz:
https://doaj.org/article/65db8512be214345b8f57462971f9d01
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33142 (2012)
Control of macrophage capacity for apoptotic cell clearance by soluble mediators such as cytokines, prostaglandins and lipoxins, serum proteins, and glucocorticoids may critically determine the rate at which inflammation resolves. Previous studies su
Externí odkaz:
https://doaj.org/article/72d1e908db5e45a385f7db7160b83b7d
Autor:
Ana L Alessandri, Rodger Duffin, Andrew E Leitch, Christopher D Lucas, Tara A Sheldrake, David A Dorward, Nik Hirani, Vanessa Pinho, Lirlândia Pires de Sousa, Mauro M Teixeira, John F Lyons, Christopher Haslett, Adriano G Rossi
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25683 (2011)
Eosinophils not only defend the body against parasitic infection but are also involved in pathological inflammatory allergic diseases such as asthma, allergic rhinitis and contact dermatitis. Clearance of apoptotic eosinophils by macrophages is a key
Externí odkaz:
https://doaj.org/article/c1a3b7d4cbea493cac69e41a520b8a9c
Autor:
Brian J. McHugh, Jillian Stephen, Calum T. Robb, Sarah Fox, Tiina Kipari, Jennifer A. Cartwright, Christopher Haslett, Rodger Duffin, Christopher D. Lucas, Adriano G. Rossi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cyclin-dependent kinase (CDK) inhibitor drugs (CDKi), such as R-roscovitine and AT7519, induce neutrophil apoptosis in vitro and enhance the resolution of inflammation in a number of in vivo models. This class of compounds are potential novel therape
Externí odkaz:
https://doaj.org/article/dd647f36378d4af591bcb325f83313a5
Background Uncontrolled inflammation contributes to the progression of organ damage in acute conditions, such as acetaminophen-induced acute liver injury (APAP-ALI) and there are limited treatments for this condition. AT7519, a cyclic-dependent kinas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393aabf13a91040f1da51d36ba5159dd
https://doi.org/10.21203/rs.3.rs-2673710/v1
https://doi.org/10.21203/rs.3.rs-2673710/v1
Publikováno v:
Gastro Hep Advances.