Zobrazeno 1 - 10
of 275
pro vyhledávání: '"Adriano D. Andricopulo"'
Autor:
Brian W. Slafer, Marco A. Dessoy, Ramon G. de Oliveira, Maria C. Mollo, Eun Lee, An Matheeussen, Louis Maes, Guy Caljon, Leonardo L. G. Ferreira, Renata Krogh, Adriano D. Andricopulo, Luiza R. Cruz, Charles E. Mowbray, Jadel M. Kratz, Luiz C. Dias
Publikováno v:
ACS Omega, Vol 9, Iss 20, Pp 22360-22370 (2024)
Externí odkaz:
https://doaj.org/article/181f8460774544aa8d922443939c65c7
Autor:
Marilia Valli, Thiago H. Döring, Edgard Marx, Leonardo L. G. Ferreira, José L. Medina-Franco, Adriano D. Andricopulo
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 1033 (2024)
The development of new treatments for neglected tropical diseases (NTDs) remains a major challenge in the 21st century. In most cases, the available drugs are obsolete and have limitations in terms of efficacy and safety. The situation becomes even m
Externí odkaz:
https://doaj.org/article/4137cad28837453da4bbf95bd02e1a64
Autor:
Alejandro Gómez-García, Daniel A. Acuña Jiménez, William J. Zamora, Haruna L. Barazorda-Ccahuana, Miguel Á. Chávez-Fumagalli, Marilia Valli, Adriano D. Andricopulo, Vanderlan da S. Bolzani, Dionisio A. Olmedo, Pablo N. Solís, Marvin J. Núñez, Johny R. Rodríguez Pérez, Hoover A. Valencia Sánchez, Héctor F. Cortés Hernández, José L. Medina-Franco
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1388 (2023)
The number of databases of natural products (NPs) has increased substantially. Latin America is extraordinarily rich in biodiversity, enabling the identification of novel NPs, which has encouraged both the development of databases and the implementat
Externí odkaz:
https://doaj.org/article/a79876af93284f3a850bb4773f0b49fc
Autor:
Daniel B. Roquini, Gabriel L. Silva, Leonardo L. G. Ferreira, Adriano D. Andricopulo, Polrat Wilairatana, Josué De Moraes
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Human helminthiasis affects approximately one in five people in the world and disproportionally affects the poorest and most deprived communities. Human angiostrongyliasis, caused by nematode Angiostrongylus cantonensis, is a neglected emerging disea
Externí odkaz:
https://doaj.org/article/f8c8d9431cbe416babb044230574c041
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/a730e7f3c3754fdcb9179a586ff0e0a4
Publikováno v:
Estudos Avançados, Vol 34, Iss 100, Pp 7-27 (2020)
resumo Existem no mundo cerca de 2.000 registros de ensaios clínicos para a investigação de medicamentos aprovados e outros candidatos para a Covid-19, incluindo moléculas pequenas e medicamentos biológicos, sem contar as vacinas. O reposicionam
Externí odkaz:
https://doaj.org/article/f57b8713b4034e52a1d86b1b9f8a9261
Autor:
Rogério P. Xavier, Ana C. Mengarda, Marcos P. Silva, Daniel B. Roquini, Maria C. Salvadori, Fernanda S. Teixeira, Pedro L. Pinto, Thiago R. Morais, Leonardo L. G. Ferreira, Adriano D. Andricopulo, Josué de Moraes
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Background Schistosomiasis is a socioeconomically devastating parasitic infection afflicting hundreds of millions of people and animals worldwide. It is the most important helminth infection, and its treatment relies solely on the drug prazi
Externí odkaz:
https://doaj.org/article/2eb280a93e1a48be8e0834eceb1b9ebb
Autor:
Ivani Pauli, Celso de O. Rezende Jr., Brian W. Slafer, Marco A. Dessoy, Mariana L. de Souza, Leonardo L. G. Ferreira, Abraham L. M. Adjanohun, Rafaela S. Ferreira, Luma G. Magalhães, Renata Krogh, Simone Michelan-Duarte, Ricardo Vaz Del Pintor, Fernando B. R. da Silva, Fabio C. Cruz, Luiz C. Dias, Adriano D. Andricopulo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Cruzain, the main cysteine protease of Trypanosoma cruzi, plays key roles in all stages of the parasite’s life cycle, including nutrition acquisition, differentiation, evasion of the host immune system, and invasion of host cells. Thus, inhibition
Externí odkaz:
https://doaj.org/article/8b05c18bef4c4cee9ab7ee11d594e168
Autor:
Aldo S. de Oliveira, Luana C. Llanes, Ricardo J. Nunes, Catharina Nucci-Martins, Anacleto S. de Souza, David L. Palomino-Salcedo, María J. Dávila-Rodríguez, Leonardo L. G. Ferreira, Adair R. S. Santos, Adriano D. Andricopulo
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The synthesis and antioxidant, antinociceptive and antiedematogenic activities of sulfonamides derived from carvacrol—a druglike natural product—are reported. The compounds showed promising antioxidant activity, and sulfonamide derived from morph
Externí odkaz:
https://doaj.org/article/07ca78a81f984448bf1d9ef595d087f9
Autor:
Eloi M. Lago, Marcos P. Silva, Talita G. Queiroz, Susana F. Mazloum, Vinícius C. Rodrigues, Paulo U. Carnaúba, Pedro L. Pinto, Jefferson A. Rocha, Leonardo L.G. Ferreira, Adriano D. Andricopulo, Josué de Moraes
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 370-379 (2019)
Background: Treatment and control of schistosomiasis, one of the most insidious and serious parasitic diseases, depend almost entirely on a single drug, praziquantel. Since the funding for drug development for poverty-associated diseases is very limi
Externí odkaz:
https://doaj.org/article/fc5227ff645b4538a8366f450cdc8876