Zobrazeno 1 - 10
of 449
pro vyhledávání: '"Adriano, Chiò"'
Autor:
Mario Stanziano, Davide Fedeli, Umberto Manera, Stefania Ferraro, Jean P. Medina Carrion, Sara Palermo, Paola Sciortino, Maurizio Cogoni, Federica Agosta, Silvia Basaia, Massimo Filippi, Marina Grisoli, Maria C. Valentini, Filippo De Mattei, Antonio Canosa, Andrea Calvo, Maria G. Bruzzone, Adriano Chiò, Anna Nigri, Cristina Moglia
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 686-697 (2024)
Abstract Objective The resting‐state functional connectome has not been extensively investigated in amyotrophic lateral sclerosis (ALS) spectrum disease, in particular in relationship with patients' genetic status. Methods Here we studied the netwo
Externí odkaz:
https://doaj.org/article/68b52a1f10cc4004a9173b7b27d00b3c
Autor:
Maurizio Grassano, Umberto Manera, Fabiola De Marchi, Paolo Cugnasco, Enrico Matteoni, Margherita Daviddi, Luca Solero, Alessandro Bombaci, Francesca Palumbo, Rosario Vasta, Antonio Canosa, Paolina Salamone, Giuseppe Fuda, Federico Casale, Letizia Mazzini, Andrea Calvo, Cristina Moglia, Adriano Chiò
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 9, Pp 1623-1632 (2023)
Abstract Background Systemic inflammation has been proposed as a relevant mechanism in amyotrophic lateral sclerosis (ALS). Still, comprehensive data on ALS patients' innate and adaptive immune responses and their effect on the clinical phenotype are
Externí odkaz:
https://doaj.org/article/25c1bc3aac9943a0a7a952f2d3ffa46b
Autor:
Sean W. Willemse, Kit C. B. Roes, Philip Van Damme, Orla Hardiman, Caroline Ingre, Monica Povedano, Naomi R. Wray, Marleen Gijzen, Mirjam S. de Pagter, Koen C. Demaegd, Annemarie F. C. Janse, Roel G. Vink, Boudewijn T. H. M. Sleutjes, Adriano Chiò, Philippe Corcia, Evy Reviers, Ammar Al-Chalabi, Matthew C. Kiernan, Leonard H. van den Berg, Michael A. van Es, Ruben P. A. van Eijk
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background Given the large genetic heterogeneity in amyotrophic lateral sclerosis (ALS), it seems likely that genetic subgroups may benefit differently from treatment. An exploratory meta-analysis identified that patients homozygous for the
Externí odkaz:
https://doaj.org/article/30fbd5e916074b949d8c09f8b72ea468
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
A wide range of neurological manifestations have been reported during the COVID-19 pandemic, including a variety of Parkinsonian cases. The association of numerous viruses with the development of persistent or transient Parkinsonism has been well-doc
Externí odkaz:
https://doaj.org/article/5875bbe71aca4fe882f712fefbf6b329
Autor:
Umberto Manera, Maria Claudia Torrieri, Cristina Moglia, Antonio Canosa, Rosario Vasta, Francesca Palumbo, Enrico Matteoni, Sara Cabras, Maurizio Grassano, Alessandro Bombaci, Alessio Mattei, Michela Bellocchia, Giuseppe Tabbia, Fulvia Ribolla, Adriano Chiò, Andrea Calvo
Publikováno v:
Brain Sciences, Vol 14, Iss 2, p 157 (2024)
Respiratory failure assessment is among the most debatable research topics in amyotrophic lateral sclerosis (ALS) clinical research due to the wide heterogeneity of its presentation. Among the different pulmonary function tests (PFTs), maximal volunt
Externí odkaz:
https://doaj.org/article/544ef28026c642d69df74f3affc9e44b
Autor:
Corrado Pancotti, Giovanni Birolo, Cesare Rollo, Tiziana Sanavia, Barbara Di Camillo, Umberto Manera, Adriano Chiò, Piero Fariselli
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Amyotrophic lateral sclerosis (ALS) is a highly complex and heterogeneous neurodegenerative disease that affects motor neurons. Since life expectancy is relatively low, it is essential to promptly understand the course of the disease to bett
Externí odkaz:
https://doaj.org/article/9ed27232ea8a4c4d89c4550720e76624
Autor:
Umberto Manera, Maurizio Grassano, Enrico Matteoni, Alessandro Bombaci, Rosario Vasta, Francesca Palumbo, Maria Claudia Torrieri, Paolo Cugnasco, Cristina Moglia, Antonio Canosa, Adriano Chiò, Andrea Calvo
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Respiratory failure is the most common cause of death in patients with amyotrophic lateral sclerosis (ALS) and occurs with great variability among patients according to different phenotypic features. Early predictors of respiratory failure in ALS are
Externí odkaz:
https://doaj.org/article/34eb1190dcd04fbf8c121b652071e5fb
Autor:
Zhongbo Chen, Regina H. Reynolds, Antonio F. Pardiñas, Sarah A. Gagliano Taliun, Wouter van Rheenen, Kuang Lin, Aleksey Shatunov, Emil K. Gustavsson, Isabella Fogh, Ashley R. Jones, Wim Robberecht, Philippe Corcia, Adriano Chiò, Pamela J. Shaw, Karen E. Morrison, Jan H. Veldink, Leonard H. van den Berg, Christopher E. Shaw, John F. Powell, Vincenzo Silani, John A. Hardy, Henry Houlden, Michael J. Owen, Martin R. Turner, Mina Ryten, Ammar Al-Chalabi
Publikováno v:
Neurobiology of Disease, Vol 180, Iss , Pp 106082- (2023)
Humans are thought to be more susceptible to neurodegeneration than equivalently-aged primates. It is not known whether this vulnerability is specific to anatomically-modern humans or shared with other hominids. The contribution of introgressed Neand
Externí odkaz:
https://doaj.org/article/f01fd2a5dcf3454199658ca3a44ca0e9
Autor:
Giovanni De Marco, Annarosa Lomartire, Umberto Manera, Antonio Canosa, Maurizio Grassano, Federico Casale, Giuseppe Fuda, Paolina Salamone, Maria Teresa Rinaudo, Sebastiano Colombatto, Cristina Moglia, Adriano Chiò, Andrea Calvo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The aetiology of Amyotrophic Lateral Sclerosis (ALS) is still poorly understood. The discovery of genetic forms of ALS pointed out the mechanisms underlying this pathology, but also showed how complex these mechanisms are. Excitotoxicity is
Externí odkaz:
https://doaj.org/article/e0f957fdf779424b97ac6858f58e9b86
Autor:
Anna Nigri, Manera Umberto, Mario Stanziano, Stefania Ferraro, Davide Fedeli, Jean Paul Medina Carrion, Sara Palermo, Laura Lequio, Federica Denegri, Federica Agosta, Massimo Filippi, Maria Consuelo Valentini, Antonio Canosa, Andrea Calvo, Adriano Chiò, Maria Grazia Bruzzone, Cristina Moglia
Publikováno v:
NeuroImage: Clinical, Vol 38, Iss , Pp 103400- (2023)
Objective: C9orf72 mutation carriers with different neurological phenotypes show cortical and subcortical atrophy in multiple different brain regions, even in pre-symptomatic phases. Despite there is a substantial amount of knowledge, small sample si
Externí odkaz:
https://doaj.org/article/e482382f222f43458db36e5c912e3f4b