Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Adrianne M Rosales"'
Autor:
David A Castilla-Casadiego, Katherine A Miranda-Muñoz, Jesse L Roberts, Anne D Crowell, David Gonzalez-Nino, Dipankar Choudhury, Frank O Aparicio-Solis, Shannon L Servoss, Adrianne M Rosales, Gary Prinz, Min Zou, Yuntao Zhang, Johann F Coetzee, Lauren F Greenlee, Jeremy Powell, Jorge Almodovar
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272169 (2022)
Microneedle patches are a promising source for transdermal diffusion of macromolecules and are designed to painlessly penetrate the skin. In this study, a biodegradable chitosan microneedle patch to deliver meloxicam for managing pain in cattle was t
Externí odkaz:
https://doaj.org/article/cbb414d6ce4c4e2981b19efdddd25cef
Autor:
Alexander Hillsley, Matthew S. Santoso, Sean M. Engels, Kathleen N. Halwachs, Lydia M. Contreras, Adrianne M. Rosales
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Myofibroblasts are a highly secretory and contractile cell phenotype that are predominant in wound healing and fibrotic disease. Traditionally, myofibroblasts are identified by the de novo expression and assembly of alpha-smooth muscle actin
Externí odkaz:
https://doaj.org/article/174853a42eff48a68619bc0daadae5b0
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Cardiac fibrosis is a pathological process characterized by excessive tissue deposition, matrix remodeling, and tissue stiffening, which eventually leads to organ failure. On a cellular level, the development of fibrosis is associated with t
Externí odkaz:
https://doaj.org/article/b44ba0f6c560436a94cdb7e5c91f61d1
Autor:
Mahsa Haseli, David A. Castilla-Casadiego, Luis Pinzon-Herrera, Alexander Hillsley, Katherine A. Miranda-Munoz, Srikanth Sivaraman, Adrianne M. Rosales, Raj R. Rao, Jorge Almodovar
Publikováno v:
Materials Today Bio, Vol 13, Iss , Pp 100194- (2022)
Human mesenchymal stromal cells (hMSCs) are multipotent cells that have been proposed for cell therapies due to their immunosuppressive capacity that can be enhanced in the presence of interferon-gamma (IFN-γ). In this study, multilayers of heparin
Externí odkaz:
https://doaj.org/article/1a6b4057581f4da9b34253167a16dd13
Autor:
Aaron A. Burkey, Neda Ghousifam, Alexander V. Hillsley, Zachary W. Brotherton, Mahboobeh Rezaeeyazdi, Taylor A. Hatridge, Dale T. Harris, William W. Sprague, Brittany E. Sandoval, Adrianne M. Rosales, Marissa Nichole Rylander, Nathaniel A. Lynd
Publikováno v:
Biomacromolecules. 24:1475-1482
Autor:
Hattie C. Schunk, Mariah J. Austin, Bradley Z. Taha, Matthew S. McClellan, Laura J. Suggs, Adrianne M. Rosales
Publikováno v:
Molecular Systems Design & Engineering. 8:92-104
Adaptable degradative responses to multiple biological stimuli are of great importance for biorecognition. Here, enzymatic and ROS degradability are tuned by monomer identity and sequence in a series of sequence-defined oligomers.
Autor:
Allison M. Green, Sanket Kadulkar, Zachary M. Sherman, Thomas M. Fitzsimons, Charles K. Ofosu, Jiajun Yan, David Zhao, Jan Ilavsky, Adrianne M. Rosales, Brett A. Helms, Venkat Ganesan, Thomas M. Truskett, Delia J. Milliron
Publikováno v:
The Journal of Physical Chemistry C. 126:19507-19518
Depletion-driven assembly has been widely studied for micron-sized colloids, but questions remain at the nanoscale where the governing physics are impacted by the stabilizing surface ligands or wrapping polymers, whose length scales are on the same o
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Cardiac fibrosis is a pathological process characterized by excessive tissue deposition, matrix remodeling, and tissue stiffening, which eventually leads to organ failure. On a cellular level, the development of fibrosis is associated with the activa
Autor:
Mariah J. Austin, Hattie Schunk, Carolyn Watkins, Natalie Ling, Jeremy Chauvin, Logan Morton, Adrianne M. Rosales
Publikováno v:
Biomacromolecules. 23(11)
Proteases, especially MMPs, are attractive biomarkers given their central role in both physiological and pathological processes. Distinguishing MMP activity with degradable substrates, however, is a difficult task due to overlapping substrate specifi
Publikováno v:
Acta biomaterialia. 155
Synthetic hydrogels are attractive platforms due in part to their highly tunable mechanics, which impact cell behavior and secretory profile. These mechanics are often controlled by altering the number of crosslinks or the total polymer concentration