Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Adriane Ferreira de Brito"'
Autor:
Ianca Gontijo Cavalcante Santana, Lorena de Souza Almeida, Lorrane Kelle da Silva Moreira, Flávio Silva de Carvalho, Ricardo Menegatti, André Luis Batista da Rocha, Thais Aline Mazurok, Boniek Gontijo Vaz, Luciano Morais Lião, Adriane Ferreira de Brito, James Oluwagbamigbe Fajemiroye, Elson Alves Costa, Pablinny Moreira Galdino de Carvalho
Publikováno v:
Canadian journal of physiology and pharmacology. 100(6)
Anxiety and depression are common mental disorders affecting millions of people worldwide. Unsatisfactory clinical outcomes with the use of the available pharmacological interventions among some patients demand newer drugs with proven efficacy, safet
Autor:
Ruth Ellen Nascimento Holanda, Eduardo Souza Santana, Glaucia Nattany Firmiano Fernandes, Caroline Castro de Araújo, Cléia Grazielle Lima do Valle Cardoso, Xisto Sena Passos, Adriane Ferreira de Brito
Publikováno v:
RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218. 4:e422790
Objetivo - Este estudo teve por objetivo analisar o consumo alimentar em crianças autistas, bem como deficiências nutricionais e possíveis doenças associadas, descrevendo sugestões alimentares para esse público. Métodos - Foram selecionados po
Autor:
Adriane Ferreira de Brito, Ricardo Menegatti, Dayane Moreira da Silva, Lorrane Kelle da Silva Moreira, Pablinny Moreira Galdino de Carvalho, Elson Alves Costa, Paulo César Ghedini, Lorrayne Siqueira, Daiany Priscilla Bueno da Silva, Carina Sofia Cardoso, Iziara Ferreira Florentino
Publikováno v:
Behavioural brain research. 401
Major depression disorder (MDD) is one of the most widespread and debilitating psychiatric diseases and may be associated with other mental disorders such as anxiety. Despite advances in neurobiology studies, currently no established mechanism can ex
Autor:
Boniek G. Vaz, Germán Sanz, Adriane Ferreira de Brito, Luciano M. Lião, Ianca Gontijo Cavalcante Santana, Carina Sofia Cardoso, Daiany Priscilla Bueno da Silva, Danillo Ramos de Oliveira, Fábio Fagundes da Rocha, Elson Alves Costa, Pablinny Moreira Galdino, Flávio Silva de Carvalho, Dayane Moreira da Silva, Lorrane Kelle da Silva Moreira, Ricardo Menegatti
Publikováno v:
Biomedicine & Pharmacotherapy. 103:546-552
The piperazine derivatives correspond to an extensive chemical class of compounds with numerous neuropharmacological activities, including antidepressant (e.g., nefazodone, trazodone) and anxiolytic (e.g., buspirone) properties. Therefore, aiming to
Autor:
Germán Sanz, Ricardo Menegatti, Boniek G. Vaz, Luciano M. Lião, Daiany P.B. Silva, James Oluwagbamigbe Fajemiroye, Adriane Ferreira de Brito, Flávio Silva de Carvalho, Elson Alves Costa, Paulo César Ghedini, Dayane Moreira da Silva, Hiasmin Franciely da Silva Neri
Publikováno v:
Chemical Biology & Drug Design. 90:432-442
In this study, we proposed the design, synthesis of a new compound 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan-1-ol (LQFM032), and pharmacological evaluation of its anxiolytic-like effect. This new compound was subjected to pharmacolo
Autor:
Germán Sanz, Boniek G. Vaz, Crisciele Fontana, Elson Alves Costa, Fábio Fagundes da Rocha, Luciano M. Lião, Ricardo Menegatti, Hugo Verli, Adriane Ferreira de Brito, Lorrane Kelle da Silva Moreira, Flávio Souza de Carvalho
Publikováno v:
Behavioural Brain Research. 394:112827
Piperazine derivatives are an attractive class of chemical compounds for the treatment of various mental illness. Herein, we demonstrated the synthesis of LQFM212, a piperazine derivative, behavioral evaluation in mice and computational studies. In n
Autor:
Lorrane Kelle da Silva Moreira, Adriane Ferreira de Brito, Ricardo Menegatti, Elson Alves Costa
Publikováno v:
Fundamentalclinical pharmacology. 33(1)
Medicinal chemistry is a science applied to the search and discovery of new therapeutic agents for the treatment of various diseases. Therefore, promising structures have been identified; one of these structures is the piperazine moiety, a cyclic mol
Autor:
Géssica A. Vasconcelos, Boniek G. Vaz, Marcella Ferreira Rodrigues, Iziara Ferreira Florentino, Daiany Priscilla Bueno da Silva, Kátia Flávia Fernandes, Elson Alves Costa, Adriane Ferreira de Brito, Verônica Vale Carvalho, Marcus Antônio Pereira-Junior, Lorrane Kelle da Silva Moreira
Publikováno v:
Journal of ethnopharmacology. 213
Ethnopharmacological relevance The cashew gum (Anacardium occidentale L.) is used in traditional Brazilian medicine in the treatment of inflammatory conditions, asthma, diabetes, and gastrointestinal disturbances. Aim of the study In the present stud
Autor:
Elson Alves Costa, Iziara Ferreira Florentino, Pablinny Moreira Galdino, Fábio Fagundes da Rocha, Daiany Priscilla Bueno da Silva, Dayane Moreira da Silva, James Oluwagbamigbe Fajemiroye, Adriane Ferreira de Brito, Danillo Ramos de Oliveira
Publikováno v:
CNSneurological disorders drug targets. 17(4)
Background: Major depressive disorder is a psychiatric disorder that affects 4.4% of the population worldwide. Although the majority of antidepressant drugs ameliorate depressive symptoms, there is still a need for safer and more effective antidepres
Autor:
Iziara Ferreira Florentino, Roberto do Nascimento Silva, Marcus Vinícius Mariano Nascimento, Pablinny Moreira Galdino, Adriane Ferreira de Brito, Elson Alves Costa, Frederico Argollo Vanderlinde, José Realino de Paula
Publikováno v:
Natural Product Research. 26:2274-2279
Spiranthera odoratissima A. St.-Hil., 'manacá', is a medicinal species used in Brazil, especially in central region, for the treatment of several diseases such as pain and inflammation. In this study, the methanol/aqueous phase of the ethanol extrac