Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Adriane E. Schilling"'
Autor:
Kingsley H. Nelson, Lynne E. Ozgur, Laura L. Rokosz, Adriane E. Schilling, Taveras Arthur G, Wei Wang, Kaiser Bernd, Ge Li, Chao Jianping, Tara M. Stauffer, J. Robert Merritt, Baldwin John J, Michael P. Dwyer
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:4107-4110
A novel series of 3,4-diaminocyclobut-3-ene-1,2-diones was prepared and found to show potent inhibitory activity of CXCR2 binding and IL-8-mediated chemotaxis of a CXCR2-expressing cell line. Microsome stability and Caco2 studies were subsequently us
Autor:
Jennifer Tullai, Linda K. Jolliffe, Adriane E. Schilling, Steven A. Middleton, Mulcahy Linda, Dana L. Johnson, Francis P. Barbone, Frank J. McMahon, Robert H. Gruninger
Publikováno v:
Journal of Biological Chemistry. 272:4985-4992
Mutagenesis of the erythropoietin receptor (EPOR) permits analysis of the contribution that individual amino acid residues make to erythropoietin (EPO) binding. We employed both random and site-specific mutagenesis to determine the function of amino
Autor:
Adriane E. Schilling, Robert A. Horlick, Robert Swanson, Alan K. Robbins, V.Danial Fitzpatrick, Bassam Damaj, Philippe Samama
Publikováno v:
Gene. 243(1-2)
Episomal vectors offer a powerful alternative to integrative recombination for transgene expression in mammalian cells. In this study, various combinations of G protein-coupled receptors (GPCRs) and the G protein subunit Gi2α, were stably expressed
Autor:
Megan B Thorn, Barbara Strohl, Robert A. Horlick, Roland E. Dolle, Bassam Damaj, Gonghua Pan, Nolan H. Sigal, Baldwin John J, Riviello Christopher, Adriane E. Schilling, V.Danial Fitzpatrick, Jorge Quintero, Ilana L. Stroke, Ming You, Maria L. Webb, Ohlmeyer Michael, Vidyadhar M. Paradkar
Publikováno v:
Immunopharmacology. 43(2-3)
Screening Pharmacopeia's encoded combinatorial libraries has led to the identification of potent, selective, competitive antagonists at the bradykinin Bl receptor. Libraries were screened using a displacement assay of [ 3 H]-des-Arg 10 -kallidir ([ 3