Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Adriana Yndart"'
Autor:
Adriana Yndart Arias, Kamila Vadell, Arti Vashist, Nagesh Kolishetti, Madepalli K. Lakshmana, Madhavan Nair, Juan P. Liuzzi
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundFinding new strategies to treat cognitive disorders is a challenging task. Medication must defeat the blood–brain barrier. Cannabidiol (CBD), a non-intoxicating compound of the cannabis plant, has gained recognition as a nutraceutical for
Externí odkaz:
https://doaj.org/article/c6ed513fa3034d8488e4596f37105c12
Autor:
Adriana Yndart Arias, Nagesh Kolishetti, Arti Vashist, Lakshmana Madepalli, Lorgeleys Llaguno, Madhavan Nair
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Human immunodeficiency virus (HIV) infection is associated with a chronic inflammatory stage and continuous activation of inflammasome pathway. We studied the anti-inflammatory effects of the compound cannabidiol (CBD) in comparison with Δ
Externí odkaz:
https://doaj.org/article/6a71afd8a7b5412e814ba0047b511d0a
Autor:
Allen Caobi, Jesenia Bonilla, Mario Gomez, Mickensone Andre, Adriana Yndart, Francisco A. Fernandez-Lima, Madhavan P. Nair, Andrea D. Raymond
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Opiate abuse increases the risk of HIV transmission and exacerbates HIV neuropathology by increasing inflammation and modulating immune cell function. Exosomal EVs(xEV) contain miRNAs that may be differentially expressed due to HIV infection or opiat
Externí odkaz:
https://doaj.org/article/8c0a3a3d1577429b8f858c344027ebf2
Autor:
Sukanya Bhunia, Nagesh Kolishetti, Arti Vashist, Adriana Yndart Arias, Deborah Brooks, Madhavan Nair
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2658 (2023)
Brain cancers and neurodegenerative diseases are on the rise, treatments for central nervous system (CNS) diseases remain limited. Despite the significant advancement in drug development technology with emerging biopharmaceuticals like gene therapy o
Externí odkaz:
https://doaj.org/article/ad9790e7e99649ecb25f785c13d8fbc2
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Despite the significant advances in neurology, the cure for neurodegenerative conditions remains a formidable task to date. Among various factors arising from the complex etiology of neurodegenerative diseases, neuroinflammation and oxidative stress
Externí odkaz:
https://doaj.org/article/60a2bc61d1ef49dbb9d77acb526aa581
Autor:
Venkata Subba Rao Atluri, Sneham Tiwari, Melisa Rodriguez, Ajeet Kaushik, Adriana Yndart, Nagesh Kolishetti, Mohan Yatham, Madhavan Nair
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2020)
Alzheimer’s disease (AD) is a growing global threat to healthcare in the aging population. In the USA alone, it is estimated that one in nine persons over the age of 65 years is living with AD. The pathology is marked by the accumulation of amyloid
Externí odkaz:
https://doaj.org/article/b745ef1735b44cc895693f646bb4a5c5
Autor:
Sneham Tiwari, Venkata Subba Rao Atluri, Adriana Yndart Arias, Rahul Dev Jayant, Ajeet Kaushik, Jonathan Geiger, Madhavan N. Nair
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Neurological disorders are the biggest concern globally. Out of ~36 million human immunodeficiency virus (HIV) positive people, about 30%–60% exhibit neurological disorders, including dementia and Alzheimer’s disease (AD) like pathology. In AD or
Externí odkaz:
https://doaj.org/article/99111a4a6ab748eb95bed22d6320e0dd
Autor:
Marisela Agudelo, Gloria Figueroa, Tiyash Parira, Adriana Yndart, Karla Muñoz, Venkata Atluri, Thangavel Samikkannu, Madhavan P Nair
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156421 (2016)
Epigenetic mechanisms have been shown to play a role in alcohol use disorders (AUDs) and may prove to be valuable therapeutic targets. However, the involvement of histone deacetylases (HDACs) on alcohol-induced oxidative stress of human primary monoc
Externí odkaz:
https://doaj.org/article/ffd2e028991d4e0b851ac1b6507bf58b
Autor:
Kesava Rao Venkata Kurapati, Thangavel Samikkannu, Venkata Subba Rao Atluri, Elena Kaftanovskaya, Adriana Yndart, Madhavan P N Nair
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112818 (2014)
Alzheimer's disease (AD) is characterized by progressive dysfunction of memory and higher cognitive functions with abnormal accumulation of extracellular amyloid plaques and intracellular neurofibrillary tangles throughout cortical and limbic brain r
Externí odkaz:
https://doaj.org/article/8626e0e6d21c480b9ae40596eb9fbd65
Autor:
Jessica Napuri, Sudheesh Pilakka-Kanthikeel, Andrea Raymond, Marisela Agudelo, Adriana Yndart-Arias, Shailendra K Saxena, Madhavan Nair
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83682 (2013)
Cocaine and other drugs of abuse increase HIV-induced immunopathogenesis; and neurobiological mechanisms of cocaine addiction implicate a key role for microRNAs (miRNAs), single-stranded non-coding RNAs that regulate gene expression and defend agains
Externí odkaz:
https://doaj.org/article/90755d440ccb4c159d4b242e3c86fe4d