C-Terminal end and aminoacid Lys48 in HMG-CoA lyase are involved in substrate binding and enzyme activity

Autor: Eduardo López-Viñas, Gabriel Santpere, Fausto G. Hegardt, Paulino Gómez-Puertas, Sebastián Menao, Juan Pié, Adriana Y. Sierra, Patricia Carrasco, Josep Clotet, Esther Gratacós, Núria Casals, Beatriz Puisac

Publikováno v: Molecular Genetics and Metabolism. 91:120-127

3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) lyase adopts a (betaalpha)(8) TIM barrel structure with an additional beta9, alpha11 and alpha12 helices. Location of HMG part of the substrate has been suggested but the binding mode for the CoA moiety remain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46aed7c2238fea8a76205dcc92378663
https://doi.org/10.1016/j.ymgme.2007.03.007

Plasmodium vivax merozoite surface protein 8 cloning, expression, and characterisation

Autor: Yolanda Lopez, Camilo Moncada, Manuel A. Patarroyo, Elizabeth Torres, Carlos A. Barrero, Adriana Y. Sierra, Luz Mary Salazar, Jimena Cortés, Oscar Perez-Leal, Pilar Martinez

Publikováno v: Biochemical and Biophysical Research Communications. 324:1393-1399

Plasmodium vivax, one of the four parasite species causing malaria in humans, is the most widespread throughout the world, leading to nearly 80 million cases per year, mainly in Latin-America and Asia. An open reading frame encoding the Plasmodium fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f17c06767d7905cf822ab19f6ff11d
https://doi.org/10.1016/j.bbrc.2004.09.202

CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity

Autor: Patricia Carrasco, Guillermina Asins, Jesús M. Ureña, Dolors Serra, Josep Clotet, Núria Casals, Adriana Y. Sierra, Esther Gratacós, Fausto G. Hegardt

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)

CPT1c is a carnitine palmitoyltransferase 1 (CPT1) isoform that is expressed only in the brain. The enzyme has recently been localized in neuron mitochondria. Although it has high sequence identity with the other two CPT1 isoenzymes (a and b), no CPT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd34debaf3603bec416f4883d351459
http://hdl.handle.net/20.500.12328/1620

Identifying and characterising the Plasmodium falciparum merozoite surface protein 10 Plasmodium vivax homologue

Autor: Luz Mary Salazar, Yolanda Lopez, Oscar Perez-Leal, Carlos A. Barrero, Pilar Martinez, Manuel A. Patarroyo, Adriana Y. Sierra, Camilo Moncada, Johan Hoebeke, Jimena Cortés

Publikováno v: Biochemical and biophysical research communications. 331(4)

Plasmodium vivax malaria is one of the most prevalent parasitic diseases in Asia and Latin-America. The difficulty of maintaining this parasite culture in vitro has hampered identifying and characterising proteins implied in merozoite invasion of red

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b93cf3ea1bdfdd5b894a654cbc82be
https://pubmed.ncbi.nlm.nih.gov/15883000

Expression, polymorphism analysis, reticulocyte binding and serological reactivity of two Plasmodium vivax MSP-1 protein recombinant fragments

Autor: Fanny Guzmán, Manuel A. Patarroyo, Ana Marı́a Espinosa, Adriana Y. Sierra, Elvia Marı́a Cantor, Libia Alexandra Cepeda, Carlos A. Barrero, Sandra Julieta Avila, Tania Bibiana Lombo

Publikováno v: Vaccine. 21(11-12)

Among the four parasite species causing malaria in humans, Plasmodium vivax prevails on both the Asian and the American continents. Several antigens from this parasite’s erythrocytic stages have been characterised and some of them are considered to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d2207714de82c3f86fc5486963f884
https://pubmed.ncbi.nlm.nih.gov/12559776