Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Adriana Turqueti-Neves"'
Autor:
Adriana Turqueti-Neves, Manuel Otte, Christian Schwartz, Michaela Erika Renate Schmitt, Cornelia Lindner, Oliver Pabst, Philipp Yu, David Voehringer
Publikováno v:
PLoS Biology, Vol 13, Iss 11, p e1002290 (2015)
IgE-mediated activation of mast cells and basophils contributes to protective immunity against helminths but also causes allergic responses. The development and persistence of IgE responses are poorly understood, which is in part due to the low numbe
Externí odkaz:
https://doaj.org/article/9f117e8859074bf5837d8ab2b47a0b95
Autor:
Elfriede Noessner, Wolfgang Uckert, Dolores J. Schendel, Thomas Blankenstein, Boris Engels, Adriana Turqueti-Neves, Matthias Leisegang
Purpose: Adoptive therapy with genetically engineered T cells carrying redirected antigen specificity is a new option for the treatment of cancer. This approach is not yet available for metastatic renal cell carcinoma (RCC), due to the scarcity of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f760b6c981c7a93014f6cd17f5cf13
https://doi.org/10.1158/1078-0432.c.6519209.v1
https://doi.org/10.1158/1078-0432.c.6519209.v1
Autor:
Elfriede Noessner, Wolfgang Uckert, Dolores J. Schendel, Thomas Blankenstein, Boris Engels, Adriana Turqueti-Neves, Matthias Leisegang
Supplementary Data from T-Cell Receptor Gene–Modified T Cells with Shared Renal Cell Carcinoma Specificity for Adoptive T-Cell Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2b92b405b509816ed743d86c08282f
https://doi.org/10.1158/1078-0432.22442495
https://doi.org/10.1158/1078-0432.22442495
Autor:
Kritika Sudan, Tillmann Michels, Carmen Amerhauser, Claudia Tschulik, Leonie Majunke, Lucille Albert, Valentina Volpin, Adriana Turqueti-Neves, Ronny Milde, Nisit Khandelwal
Publikováno v:
Cancer Research. 83:3471-3471
Tumor-associated macrophages (TAMs) are important players to maintain immunosuppression within the tumor microenvironment (TME) and attenuate the function of effector immune cells to promote tumor survival. High density of TAMs is well-recognized as
Autor:
Slavoljub Milosevic, Krystel Vincent, Daniel Sommermeyer, Dolores J. Schendel, Alexander Schmidt, Barbara Loesch, Adriana Turqueti Neves, Alexandra Kuhlenkamp, Andreas Acs, Tiziana Franceschetti, Justyna Ogonek, Claude Perreault
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A201-A201
BackgroundTransgenic T cell receptor (TCR)-based T cell therapies are a powerful treatment for cancer. However, one of the greatest remaining challenges is the successful identification of tumor-specific antigens (TSAs) that are shared between patien
Publikováno v:
Immunity. 45:1052-1065
The extrafollicular (EF) plasmablast response to self-antigens that contain Toll-like receptor (TLR) ligands is prominent in murine lupus models and some bacterial infections, but the inhibitors and activators involved have not been fully delineated.
Publikováno v:
JCI insight. 2(4)
T cells play a significant role in the pathogenesis of systemic autoimmune diseases, including systemic lupus erythematosus; however, there is relatively little information on the nature and specificity of autoreactive T cells. Identifying such cells
Autor:
Michael R. Bösl, Adriana Turqueti-Neves, Bent Brachvogel, Sebastian Brachs, Dirk Mielenz, Hans-Martin Jäck, Dorothea Reimer, Merle Stein, Thomas Winkler, David Voehringer
Publikováno v:
European Journal of Immunology. 44:3206-3219
Activated B cells are selected for in germinal centers by regulation of their apoptosis. The Ca2+ -binding cytoskeletal adaptor protein Swiprosin-1/EFhd2 (EFhd2) can promote apoptosis in activated B cells. We therefore hypothesized that EFhd2 might l
Autor:
Uta E. Höpken, Martin Lipp, David Voehringer, Manuel Otte, Thorsten Buch, Olivia Prazeres da Costa, Adriana Turqueti-Neves
Publikováno v:
European Journal of Immunology. 44:2130-2138
Infection with helminths and exposure to antigens induce a strong type 2 immune response resulting in the secretion of the cytokines IL-4 and IL-13 by CD4(+) T cells and several innate cell types. IL-4 and IL-13 promote class switch recombination to
Autor:
Wolger Lübben, Silke Storsberg, Sonja Dehnert, Volker Schmidt, Christian Stöberl, Stefan Bauer, Gert Riethmüller, Adriana Turqueti-Neves, Klaus Pfeffer, Sarah Wünsche, Anna Okhrimenko, Philipp Yu, David Voehringer, Stefanie Paul
Publikováno v:
European Journal of Immunology. 43:1231-1242
Immunoglobulin E (IgE) production is tightly regulated at the cellular and genetic levels and is believed to be central to allergy development. At least two cellular pathways exist that lead to systemic anaphylaxis reactions in vivo: IgE-sensitized m