Zobrazeno 1 - 4 of 4 pro vyhledávání: '"Adriana Tron"'
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Data from PARC and CUL7 Form Atypical Cullin RING Ligase Complexes
Autor: James A. DeCaprio, Michael P. Washburn, Selene K. Swanson, Adriana Tron, Takehiro Arai, Takeya Tsutsumi, Laurence Florens, Jeffrey R. Skaar
CUL7 and the p53-associated, PARkin-like cytoplasmic protein (PARC) were previously reported to form homodimers and heterodimers, the first demonstration of cullin dimerization. Although a CUL7-based SKP1/CUL1/F-box (SCF)–like complex has been obse
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282185ce5840ef6dec87d9e582a41792
https://doi.org/10.1158/0008-5472.c.6495932
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3
RTID-02. A PHASE 1, SAFETY LEAD-IN AND RANDOMIZED, OPEN-LABEL, PERIOPERATIVE STUDY OF VORASIDENIB COMBINED WITH PEMBROLIZUMAB IN RECURRENT OR PROGRESSIVE ENHANCING IDH-1 MUTANT ASTROCYTOMAS: TRIAL IN PROGRESS
Autor: Patrick Wen, Ingo Mellinghoff, Jennifer Clarke, Vinay Puduvalli, John de Groot, Hua Liu, Adriana Tron, Michael Chisamore, Lori Steelman, Islam Hassan, Timothy Cloughesy
Publikováno v: Neuro-Oncology. 24:vii249-vii249
BACKGROUND Astrocytomas are a subset of diffuse gliomas defined by intact 1p and 19q arms. Isocitrate dehydrogenase 1 mutations (mIDH-1) occur in ~70% of grade 2/3 gliomas, leading to accumulation of 2-hydroxyglutarate (2-HG). Vorasidenib (VOR) is an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::273b0dc9f250078491f8905937b44840
https://doi.org/10.1093/neuonc/noac209.962
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Plný text Recenzováno Digitální knihovna AV ČR
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