Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Adriana S Beltran"'
Autor:
Julie C Necarsulmer, Jeremy M Simon, Baggio A Evangelista, Youjun Chen, Xu Tian, Sara Nafees, Ariana B Marquez, Huijun Jiang, Ping Wang, Deepa Ajit, Viktoriya D Nikolova, Kathryn M Harper, J Ashley Ezzell, Feng-Chang Lin, Adriana S Beltran, Sheryl S Moy, Todd J Cohen
Publikováno v:
eLife, Vol 12 (2023)
TDP-43 proteinopathies including frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are neurodegenerative disorders characterized by aggregation and mislocalization of the nucleic acid-binding protein TDP-43 and subseque
Externí odkaz:
https://doaj.org/article/1ef60b65b631406abd7b36cb7384d395
Autor:
Samuel C Wolff, Katarzyna M Kedziora, Raluca Dumitru, Cierra D Dungee, Tarek M Zikry, Adriana S Beltran, Rachel A Haggerty, JrGang Cheng, Margaret A Redick, Jeremy E Purvis
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 9, Pp 1-9 (2018)
Abstract It is well known that clonal cells can make different fate decisions, but it is unclear whether these decisions are determined during, or before, a cell's own lifetime. Here, we engineered an endogenous fluorescent reporter for the pluripote
Externí odkaz:
https://doaj.org/article/ce877a86d66346a5a7021a2bb8a4c608
Autor:
Rachel A Battaglia, Adriana S Beltran, Samed Delic, Raluca Dumitru, Jasmine A Robinson, Parijat Kabiraj, Laura E Herring, Victoria J Madden, Namritha Ravinder, Erik Willems, Rhonda A Newman, Roy A Quinlan, James E Goldman, Ming-Der Perng, Masaki Inagaki, Natasha T Snider
Publikováno v:
eLife, Vol 8 (2019)
Alexander disease (AxD) is a fatal neurodegenerative disorder caused by mutations in glial fibrillary acidic protein (GFAP), which supports the structural integrity of astrocytes. Over 70 GFAP missense mutations cause AxD, but the mechanism linking d
Externí odkaz:
https://doaj.org/article/1a944b07b95f440191c0e5f0e38980a8
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24595 (2011)
Maspin is a tumor and metastasis suppressor playing an essential role as gatekeeper of tumor progression. It is highly expressed in epithelial cells but is silenced in the onset of metastatic disease by epigenetic mechanisms. Reprogramming of Maspin
Externí odkaz:
https://doaj.org/article/b72c57f472274a6aa31af48195c27ee4
Autor:
Alvaro A. Beltran, Sarahi G. Molina, Ariana Marquez, Lorena J. Munoz, Jose F. Olivares, Adriana S. Beltran
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102421- (2021)
The generation of induced pluripotent stem cells (iPSCs) from healthy individuals is an invaluable resource as reference control in disease modeling and drug discovery. This paper details the reprogramming of peripheral blood mononuclear cells (PBMCs
Externí odkaz:
https://doaj.org/article/af69897b9a094e00bfe5ac3d1d13dbce
Publikováno v:
Stem Cell Research, Vol 49, Iss , Pp 102015- (2020)
Induced pluripotent stem cells (iPSCs) generated from young, healthy individuals are valuable tools for investigating molecular disease mechanisms during the early development of the brain vasculature. We generated an iPSC line from peripheral blood
Externí odkaz:
https://doaj.org/article/fb58de5b5ae647cba293c831544232cc
Autor:
Gary L. Johnson, Jon S. Zawistowski, Steven P. Angus, Charlene M. Santos, Nathaniel J. Moorman, Andrew Hale, Timothy J. Stuhlmiller, Naim U. Rashid, Adriana S. Beltran, Darshan Singh, Brian T. Golitz, Noah Sciaky, Jose F. Olivares-Quintero, Samantha M. Bevill
File includes drug synergy scores for 1 cell line screened against OTX015
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a25e1d1b980bfd39e3876778cdebb5
https://doi.org/10.1158/1541-7786.22513420.v1
https://doi.org/10.1158/1541-7786.22513420.v1
Autor:
Gary L. Johnson, Jon S. Zawistowski, Steven P. Angus, Charlene M. Santos, Nathaniel J. Moorman, Andrew Hale, Timothy J. Stuhlmiller, Naim U. Rashid, Adriana S. Beltran, Darshan Singh, Brian T. Golitz, Noah Sciaky, Jose F. Olivares-Quintero, Samantha M. Bevill
File includes AlphaScreening values for activity of the screening library against the BET or p300 bromodomains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca58033c88ff333e059b8d6933e936f7
https://doi.org/10.1158/1541-7786.22513414.v1
https://doi.org/10.1158/1541-7786.22513414.v1
Autor:
Gary L. Johnson, Jon S. Zawistowski, Steven P. Angus, Charlene M. Santos, Nathaniel J. Moorman, Andrew Hale, Timothy J. Stuhlmiller, Naim U. Rashid, Adriana S. Beltran, Darshan Singh, Brian T. Golitz, Noah Sciaky, Jose F. Olivares-Quintero, Samantha M. Bevill
File contains information on small molecules included in screening library
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e500f09a798f7186892bf9a32f9e558f
https://doi.org/10.1158/1541-7786.22513426.v1
https://doi.org/10.1158/1541-7786.22513426.v1
Autor:
Gary L. Johnson, Jon S. Zawistowski, Steven P. Angus, Charlene M. Santos, Nathaniel J. Moorman, Andrew Hale, Timothy J. Stuhlmiller, Naim U. Rashid, Adriana S. Beltran, Darshan Singh, Brian T. Golitz, Noah Sciaky, Jose F. Olivares-Quintero, Samantha M. Bevill
Supplemental figures, figure legends, table legends, methods, and references
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9495352fd55781725b403c0c9eaa25e9
https://doi.org/10.1158/1541-7786.22513408
https://doi.org/10.1158/1541-7786.22513408