Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Adriana Rodríguez-Trejo"'
Autor:
Lisa Stoll, Adriana Rodríguez-Trejo, Claudiane Guay, Flora Brozzi, Mustafa Bilal Bayazit, Sonia Gattesco, Véronique Menoud, Jonathan Sobel, Ana Claudia Marques, Morten Trillingsgaard Venø, Jonathan Lou S. Esguerra, Mohammad Barghouth, Mara Suleiman, Lorella Marselli, Jørgen Kjems, Lena Eliasson, Erik Renström, Karim Bouzakri, Michel Pinget, Piero Marchetti, Romano Regazzi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Circular RNAs contribute to the regulation of β-cell specific functions. Here the authors show that a circular RNA derived from one of the introns of the insulin gene is necessary for optimal insulin secretion from pancreatic islets and that its lev
Externí odkaz:
https://doaj.org/article/114bb60757e446fba74489bec09b7aca
Autor:
Marta Menjivar, Adriana Rodríguez-Trejo, B. Blondeau, Elena Zambrano, Carmen Méndez, Peter W. Nathanielsz, Bernadette Breant, María Guadalupe Ortiz-López, María de los Ángeles Granados-Silvestre
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 302:E1431-E1439
Maternal low-protein diets (LP) impair pancreatic β-cell development, resulting in later-life failure and susceptibility to type 2 diabetes (T2D). We hypothesized that intrauterine and/or postnatal developmental programming seen in this situation in
Autor:
Adriana Rodríguez-Trejo, Marta Menjivar, Isela Montúfar-Robles, Martín Herrera-Cornejo, María de los Ángeles Granados-Silvestre, Roxana Gutiérrez-Vidal, Samuel Canizales-Quinteros, María Guadalupe Ortiz-López
Publikováno v:
Genetic Testing and Molecular Biomarkers. 15:79-83
Worldwide researchers have invested time, effort, and money during the last years to find new genes associated with diabetes susceptibility, such as LOC387761, HHEX, EXT2, and SLC30A8. The aim of the present study was to evaluate whether single-nucle
Autor:
Jonathan Sobel, Claudiane Guay, Ofer Elhanani, Adriana Rodriguez-Trejo, Lisa Stoll, Véronique Menoud, Cécile Jacovetti, Michael D. Walker, Romano Regazzi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Glucose-induced insulin secretion, a hallmark of mature β-cells, is achieved after birth and is preceded by a phase of intense proliferation. These events occurring in the neonatal period are decisive for establishing an appropriate functio
Externí odkaz:
https://doaj.org/article/b8ebcf5f93ea4a368630185da5395111
Autor:
Lisa Stoll, Jonathan Sobel, Adriana Rodriguez-Trejo, Claudiane Guay, Kailun Lee, Morten Trillingsgaard Venø, Jørgen Kjems, D. Ross Laybutt, Romano Regazzi
Publikováno v:
Molecular Metabolism, Vol 9, Iss , Pp 69-83 (2018)
Objective: There is strong evidence for an involvement of different classes of non-coding RNAs, including microRNAs and long non-coding RNAs, in the regulation of β-cell activities and in diabetes development. Circular RNAs were recently discovered
Externí odkaz:
https://doaj.org/article/661b51bcc77b40919c42421d769fdf4a
Autor:
Lisa Stoll, Adriana Rodríguez-Trejo, Claudiane Guay, Flora Brozzi, Mustafa Bilal Bayazit, Sonia Gattesco, Véronique Menoud, Jonathan Sobel, Ana Claudia Marques, Morten Trillingsgaard Venø, Jonathan Lou S. Esguerra, Mohammad Barghouth, Mara Suleiman, Lorella Marselli, Jørgen Kjems, Lena Eliasson, Erik Renström, Karim Bouzakri, Michel Pinget, Piero Marchetti, Romano Regazzi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature communications, vol. 11, no. 1, pp. 5611
Stoll, L, Rodríguez-Trejo, A, Guay, C, Brozzi, F, Bayazit, M B, Gattesco, S, Menoud, V, Sobel, J, Marques, A C, Venø, M T, Esguerra, J L S, Barghouth, M, Suleiman, M, Marselli, L, Kjems, J, Eliasson, L, Renström, E, Bouzakri, K, Pinget, M, Marchetti, P & Regazzi, R 2020, ' A circular RNA generated from an intron of the insulin gene controls insulin secretion ', Nature Communications, vol. 11, 5611 . https://doi.org/10.1038/s41467-020-19381-w
Nature Communications
Nature communications, vol. 11, no. 1, pp. 5611
Stoll, L, Rodríguez-Trejo, A, Guay, C, Brozzi, F, Bayazit, M B, Gattesco, S, Menoud, V, Sobel, J, Marques, A C, Venø, M T, Esguerra, J L S, Barghouth, M, Suleiman, M, Marselli, L, Kjems, J, Eliasson, L, Renström, E, Bouzakri, K, Pinget, M, Marchetti, P & Regazzi, R 2020, ' A circular RNA generated from an intron of the insulin gene controls insulin secretion ', Nature Communications, vol. 11, 5611 . https://doi.org/10.1038/s41467-020-19381-w
Fine-tuning of insulin release from pancreatic β-cells is essential to maintain blood glucose homeostasis. Here, we report that insulin secretion is regulated by a circular RNA containing the lariat sequence of the second intron of the insulin gene.