Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Adriana Puma"'
Autor:
Michele Massimino, Elena Tirrò, Stefania Stella, Livia Manzella, Maria Stella Pennisi, Chiara Romano, Silvia Rita Vitale, Adriana Puma, Cristina Tomarchio, Sandra Di Gregorio, Agostino Antolino, Francesco Di Raimondo, Paolo Vigneri
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Chronic Myeloid Leukemia (CML) is a hematological disorder characterized by the clonal expansion of a hematopoietic stem cell carrying the Philadelphia chromosome that juxtaposes the BCR and ABL1 genes. The ensuing BCR-ABL1 chimeric oncogene is chara
Externí odkaz:
https://doaj.org/article/e64984d411ed458d9ee29e056ad88a5f
Autor:
Elena Tirrò, Michele Massimino, Chiara Romano, Federica Martorana, Maria Stella Pennisi, Stefania Stella, Giuliana Pavone, Sandra Di Gregorio, Adriana Puma, Cristina Tomarchio, Silvia Rita Vitale, Livia Manzella, Paolo Vigneri
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Glioblastoma multiforme (GBM) is the most common primary brain malignancy and is often resistant to conventional treatments due to its extensive cellular heterogeneity. Thus, the overall survival of GBM patients remains extremely poor. Insulin-like g
Externí odkaz:
https://doaj.org/article/5b3b2a650bd34cddbfe18451893beb66
Autor:
Stefania Stella, Silvia Rita Vitale, Fabio Stagno, Michele Massimino, Adriana Puma, Cristina Tomarchio, Maria Stella Pennisi, Elena Tirrò, Chiara Romano, Francesco Di Raimondo, Emma Cacciola, Rossella Cacciola, Livia Manzella
Publikováno v:
Diagnostics, Vol 12, Iss 5, p 1051 (2022)
Background: Detection of BCR-ABL1 transcript level via real-time quantitative-polymerase-chain reaction (Q-PCR) is a clinical routine for disease monitoring, assessing Tyrosine Kinase Inhibitor therapy efficacy and predicting long-term response in ch
Externí odkaz:
https://doaj.org/article/f7d7cb5661ca4f51a9017dfe1bdc1026
Autor:
Michele Massimino, Stefania Stella, Elena Tirrò, Chiara Romano, Maria Stella Pennisi, Adriana Puma, Livia Manzella, Antonino Zanghì, Fabio Stagno, Francesco Di Raimondo, Paolo Vigneri
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-15 (2018)
Abstract The introduction of ABL Tyrosine Kinase Inhibitors (TKIs) has significantly improved the outcome of Chronic Myeloid Leukemia (CML) patients that, in large part, achieve satisfactory hematological, cytogenetic and molecular remissions. Howeve
Externí odkaz:
https://doaj.org/article/9b21a4b502ea48ec89c59850edc2e6d1
Autor:
Stefania Stella, Silvia Rita Vitale, Michele Massimino, Adriana Puma, Cristina Tomarchio, Maria Stella Pennisi, Elena Tirrò, Chiara Romano, Federica Martorana, Fabio Stagno, Francesco Di Raimondo, Livia Manzella
Publikováno v:
Diagnostics, Vol 11, Iss 8, p 1502 (2021)
Molecular testing of the BCR-ABL1 transcript via real-time quantitative-polymerase-chain-reaction is the most sensitive approach for monitoring the response to tyrosine-kinase-inhibitors therapy in chronic myeloid leukaemia (CML) patients. Each stage
Externí odkaz:
https://doaj.org/article/605f9d39700947e9b08dab2fb0be37e4
Autor:
Maria Stella Pennisi, Stefania Stella, Silvia Rita Vitale, Adriana Puma, Sandra Di Gregorio, Chiara Romano, Elena Tirrò, Michele Massimino, Agostino Antolino, Sergio Siragusa, Donato Mannina, Stefana Impera, Caterina Musolino, Giuseppe Mineo, Bruno Martino, Valentina Zammit, Francesco Di Raimondo, Livia Manzella, Fabio Stagno, Paolo Vigneri
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
In Chronic Myeloid Leukemia (CML), successful treatment requires accurate molecular monitoring to evaluate disease response and provide timely interventions for patients failing to achieve the desired outcomes. We wanted to determine whether measurin
Externí odkaz:
https://doaj.org/article/3e56e6cdd1d04b3297ce06df9e7579b6
Autor:
Livia Manzella, Maria Stella Pennisi, Cristina Tomarchio, Adriana Puma, Fabio Stagno, Silvia Rita Vitale, Sandra Di Gregorio, Loredana Tambè, Elena Tirrò, Maria Letizia Consoli, Francesco Di Raimondo, Chiara Romano
Publikováno v:
In Vivo
Background/aim The Philadelphia chromosome is considered the hallmark of chronic myeloid leukemia (CML). However, although most patients with CML are diagnosed with the e13a2 or e14a2 breakpoint cluster region (BCR)-Abelson 1 (ABL1) fusion transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da60331947e73da9f1d35380d7db7352
https://doi.org/10.21873/invivo.11933
https://doi.org/10.21873/invivo.11933
Autor:
Adriana Puma, Enrica Antonia Martino, Michele Massimino, Stefania Stella, Franscesco Di Raimondo, Maria Letizia Consoli, Chiara Romano, Fabio Stagno, Valentina Zammit, Silvia Rita Vitale, Sandra Di Gregorio, Maria Cristina Pirosa, Maria Stella Pennisi, Livia Manzella, Elena Tirrò
Publikováno v:
Anticancer Research. 39:3893-3899
Background/aim Chronic myelogenous leukemia (CML) is characterized by the presence of the Philadelphia chromosome, resulting from the reciprocal translocation involving chromosomes 9 and 22. About 5-10% of newly diagnosed patients in chronic-phase (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d92105363e120feb7210e7f62535dcf
https://doi.org/10.21873/anticanres.13540
https://doi.org/10.21873/anticanres.13540
Autor:
Maria Stella Pennisi, Stefania Stella, Livia Manzella, Francesco Di Raimondo, Michele Massimino, Adriana Puma, Chiara Romano, Sandra Di Gregorio, Fabio Stagno, Valentina Zammit, Silvia Rita Vitale, Elena Tirrò
Publikováno v:
Acta Haematologica. 141:261-267
BCR-ABL1-negative myeloproliferative disorders and chronic myeloid leukaemia are haematologic malignancies characterised by single and mutually exclusive genetic alterations. Nevertheless, several patients co-expressing the JAK2V617F mutation and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a7da030a1a9e0d08d7c0dc7dad275f4
https://doi.org/10.1159/000496821
https://doi.org/10.1159/000496821
Autor:
Michele Massimino, Sandra Di Gregorio, Stefania Stella, Silvia Rita Vitale, Adriana Puma, Maria Stella Pennisi, Paolo Vigneri, Chiara Romano, Livia Manzella, Giuseppe A. Palumbo, Elena Tirrò, Cristina Tomarchio
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 486, p 486 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 486, p 486 (2021)
Hypereosinophilia (HE) is a heterogeneous condition with a persistent elevated eosinophil count of >350/mm3, which is reported in various (inflammatory, allergic, infectious, or neoplastic) diseases with distinct pathophysiological pathways. HE may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856023a0038103bc6ede00fa0209b363
http://hdl.handle.net/20.500.11769/499065
http://hdl.handle.net/20.500.11769/499065
