Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Adriana O, Gomes"'
Autor:
Alice M. R. Bernardino, Monique Araújo de Brito, Leonor L. Leon, Mauricio S. dos Santos, Misbahul Ain Khan, Carlos Rangel Rodrigues, Adriana O. Gomes, Helena Carla Castro, Paula Alvarez Abreu, Marilene M. Canto-Cavalheiro, Rosa M. M. de Léo, Marcos C. de Souza
Publikováno v:
Journal of the Brazilian Chemical Society. 22:352-358
Chemotherapy for leishmaniasis, diseases caused by protozoa of the genus Leishmania, remains inefficient in several treatments. So there is a need to search for new drugs. In this work, we have synthesized 1-aryl-1H-pyrazole-4-carboximidamides deriva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61ddb354a3a2be7681fc5d8521bdda77
https://doi.org/10.1590/s0103-50532011000200022
https://doi.org/10.1590/s0103-50532011000200022
Autor:
Alice M. R. Bernardino, Karen dos Santos Charret, Adriana V. Carvalho, Raquel Fonseca Rodrigues, Marilene M. Canto-Cavalheiro, Adriana O. Gomes, Veronica F. Amaral, Leonor L. Leon
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 80:568-573
Newly synthesized pyrazole carbohydrazide derivatives with substituents X = Br/Y = NO 2 and X = NO 2 /Y = Cl were independently investigated in the CBA mouse model of cutaneous leishmaniasis. Animals were infected with Leishmania amazonensis and trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c442fcacd64e37d278721f041758ff5
https://doi.org/10.4269/ajtmh.2009.80.568
https://doi.org/10.4269/ajtmh.2009.80.568
Autor:
Karen S, Charret, Raquel F, Rodrigues, Alice M R, Bernardino, Adriana O, Gomes, Adriana V, Carvalho, Marilene M, Canto-Cavalheiro, Leonor, Leon, Veronica F, Amaral
Publikováno v:
The American journal of tropical medicine and hygiene. 80(4)
Newly synthesized pyrazole carbohydrazide derivatives with substituents X = Br/Y = NO(2) and X = NO(2)/Y = Cl were independently investigated in the CBA mouse model of cutaneous leishmaniasis. Animals were infected with Leishmania amazonensis and tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44a877c1077e6d34e4c3515774c65656
https://pubmed.ncbi.nlm.nih.gov/19346377
https://pubmed.ncbi.nlm.nih.gov/19346377
Autor:
Leonor L. Leon, Alice M. R. Bernardino, Veronica F. Amaral, Adriana O. Gomes, Marilene M. Canto-Cavalheiro, Antonio C. C. Freitas, Gerzia M. C. Machado, Karen dos Santos Charret
Publikováno v:
European journal of medicinal chemistry. 41(1)
1H-pyrazole-4-carbohydrazides were synthesized and their leishmanicidal in vitro activities and cytotoxic effects were investigated. The drugs prototypes of these new compounds (ketoconazole, benznidazole, allopurinol and pentamidine) were also teste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeb95803312062b16ec312dbde1ddbc
https://pubmed.ncbi.nlm.nih.gov/16300859
https://pubmed.ncbi.nlm.nih.gov/16300859
Autor:
Leonor L. Leon, Carla E. Carvalho-Pinto, Marilene M. Canto-Cavalheiro, Veronica F. Amaral, Jussara Lagrota-Cândido, Alice M. R. Bernardino, Marie-Luce F. Lira, Karen dos Santos Charret, Cristiane F. Hottz, Adriana O. Gomes, Raquel Fonseca Rodrigues
Publikováno v:
Experimental Parasitology. (2):201-210
Because there is no vaccine in clinical use, control of Leishmaniasis relies almost exclusively on chemotherapy and the conventional treatments exhibit high toxicity for patients and emerging drug resistance. Recently, we showed that oral treatment w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bc0f014fdefe5d37ee71f05683bc32