Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Adriana Martinez-Turtos"'
Autor:
Adriana Martinez-Turtos, Rachel Paul, Manuel Grima-Reyes, Hussein Issaoui, Adrien Krug, Rana Mhaidly, Jozef P. Bossowski, Johanna Chiche, Sandrine Marchetti, Els Verhoeyen, Eric Chevet, Jean-Ehrland Ricci
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
IRE1α is one of the three ER transmembrane transducers of the Unfolded Protein Response (UPR) activated under endoplasmic reticulum (ER) stress. IRE1α activation has a dual role in cancer as it may be either pro- or anti-tumoral depending on the st
Externí odkaz:
https://doaj.org/article/a17f8333685a4354820bb0d127341553
Autor:
Manuel Grima-Reyes, Adriana Martinez-Turtos, Ifat Abramovich, Eyal Gottlieb, Johanna Chiche, Jean-Ehrland Ricci
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101294- (2021)
Background: There is growing interest in the analysis of tumor metabolism to identify cancer-specific metabolic vulnerabilities and therapeutic targets. Finding of such candidate metabolic pathways mainly relies on the highly sensitive identification
Externí odkaz:
https://doaj.org/article/c849da96dbe848cba26254ae41de4557
Autor:
Alejandra Gutierrez-Guerrero, Maria Jimena Abrey Recalde, Philippe E. Mangeot, Caroline Costa, Ornellie Bernadin, Séverine Périan, Floriane Fusil, Gisèle Froment, Adriana Martinez-Turtos, Adrien Krug, Francisco Martin, Karim Benabdellah, Emiliano P. Ricci, Simone Giovannozzi, Rik Gijsbers, Eduard Ayuso, François-Loïc Cosset, Els Verhoeyen
Publikováno v:
Frontiers in Genome Editing, Vol 3 (2021)
Programmable nucleases have enabled rapid and accessible genome engineering in eukaryotic cells and living organisms. However, their delivery into human blood cells can be challenging. Here, we have utilized “nanoblades,” a new technology that de
Externí odkaz:
https://doaj.org/article/1d5485f02cd64cd39b1ee599b28883bf
Autor:
Adrien Krug, Rana Mhaidly, Marie Tosolini, Laura Mondragon, Gamze Tari, Adriana Martinez Turtos, Rachel Paul-Bellon, Vahid Asnafi, Sandrine Marchetti, Léa Di Mascio, Marion Travert, Frédéric Bost, Emmanuel Bachy, Rafael J. Argüello, Jean-Jacques Fournié, Philippe Gaulard, François Lemonnier, Jean-Ehrland Ricci, Els Verhoeyen
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Cancer metabolic reprogramming has been recognized as one of the cancer hallmarks that promote cell proliferation, survival, as well as therapeutic resistance. Up-to-date regulation of metabolism in T-cell lymphoma is poorly understood. In p
Externí odkaz:
https://doaj.org/article/7cd810306c654f90b3cc436c3f70300e
Autor:
Vignesh Ramesh, Paradesi Naidu Gollavilli, Luisa Pinna, Mohammad Aarif Siddiqui, Adriana Martinez Turtos, Francesca Napoli, Yasmin Antonelli, Aldo Leal‐Egaña, Jesper Foged Havelund, Simon Toftholm Jakobsen, Elisa Le Boiteux, Marco Volante, Nils Joakim Færgeman, Ole N Jensen, Rasmus Siersbæk, Kumar Somyajit, Paolo Ceppi
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-24 (2023)
Abstract The epithelial‐to‐mesenchymal transition (EMT) plays a central role in the development of cancer metastasis and resistance to chemotherapy. However, its pharmacological treatment remains challenging. Here, we used an EMT‐focused integr
Externí odkaz:
https://doaj.org/article/f6a02b7c4b9e494a97d706c0ba7228b7
Autor:
Manuel Grima-Reyes, Ashaina Vandenberghe, Ivan Nemazanyy, Pauline Meola, Rachel Paul, Julie Reverso-Meinietti, Adriana Martinez-Turtos, Nicolas Nottet, Wai-Kin Chan, Philip L. Lorenzi, Sandrine Marchetti, Jean-Ehrland Ricci, Johanna Chiche
Publikováno v:
Science Advances
Science Advances, 2022, 8 (27), pp.eabn6491. ⟨10.1126/sciadv.abn6491⟩
Science Advances, 2022, 8 (27), pp.eabn6491. ⟨10.1126/sciadv.abn6491⟩
Depletion of circulating asparagine with l -asparaginase (ASNase) is a mainstay of leukemia treatment and is under investigation in many cancers. Expression levels of asparagine synthetase (ASNS), which catalyzes asparagine synthesis, were considered
Autor:
Alejandra, Gutierrez-Guerrero, Maria Jimena, Abrey Recalde, Philippe E, Mangeot, Caroline, Costa, Ornellie, Bernadin, Séverine, Périan, Floriane, Fusil, Gisèle, Froment, Adriana, Martinez-Turtos, Adrien, Krug, Francisco, Martin, Karim, Benabdellah, Emiliano P, Ricci, Simone, Giovannozzi, Rik, Gijsbers, Eduard, Ayuso, François-Loïc, Cosset, Els, Verhoeyen
Publikováno v:
Frontiers in Genome Editing
Programmable nucleases have enabled rapid and accessible genome engineering in eukaryotic cells and living organisms. However, their delivery into human blood cells can be challenging. Here, we have utilized “nanoblades,” a new technology that de
Publikováno v:
Cancers
Cancers, Vol 14, Iss 183, p 183 (2022)
Cancers, Vol 14, Iss 183, p 183 (2022)
Simple Summary Cancer treatments are evolving at a very rapid pace. Some of the most novel anti-cancer medicines under development rely on the modification of immune cells in order to transform them into potent tumor-killing cells. However, the tumor