Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Adriana M. Doi"'
Autor:
Anne E. Loccisano, Brandy Riffle, Markus Frericks, Ivana Fegert, Eric Fabian, Elaine Freeman, Adriana M. Doi
Publikováno v:
Regulatory Toxicology and Pharmacology. 124:104962
Afidopyropen is an insecticide that acts as a transient receptor potential vanilloid subtype (TRPV) channel modulator in chordotonal organs of target insects and has been assessed for a wide range of toxicity endpoints including chronic toxicity and
Autor:
J. Christopher Corton, Abigail Jacobs, Adriana M. Doi, Jonathan G. Moggs, James E. Klaunig, Susan P. Felter, Arun R. Pandiri, Angela M. Lynch, Lynne T. Haber, Jennifer E. Foreman, Lynn Flowers, Alan R. Boobis, Jay I. Goodman
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 92
The Toxicology Forum sponsored a workshop in October 2016, on the human relevance of rodent liver tumors occurring via nongenotoxic modes of action (MOAs). The workshop focused on two nuclear receptor-mediated MOAs (Constitutive Androstane Receptor (
Autor:
James R. Hailey, Rajendra S. Chhabra, Molly Vallant, Milton R. Hejtmancik, Adriana M. Doi, John D. Toft
Publikováno v:
Toxicologic Pathology. 33:631-640
Widespread human exposure to multifunctional acrylates is of concern, due to their inherent reactivity and irritating properties. Trimethylolpropane triacrylate (TMPTA) and pentaerythritol triacrylate (PETA) are industrially important representatives
Publikováno v:
Journal of Toxicology and Environmental Health, Part B. 8:109-126
The carcinogenic activities of anthraquinone and six derivatives were compared and contrasted. Studies included representatives of amino, alkyl, nitro, hydroxy, or halogen-containing anthraquinones, with the purpose of uncovering general structure-ac
Autor:
Roger A. Renne, John C. Peckham, Rajendra S. Chhabra, Jeffrey A. Dill, Billy J. Chou, Adriana M. Doi, Sondra L. Grumbein
Publikováno v:
Inhalation Toxicology. 16:247-257
Stoddard solvent IIC is widely used as a solvent in paints and varnishes, and for dry cleaning and other grease removal applications. Because concern exists regarding the long-term effects of occupational exposure in industrial settings, the toxicity
Publikováno v:
Toxicology and Applied Pharmacology. 181:48-59
Studies of transplacental transfer of aflatoxin B(1) (AFB(1)) suggest that the developing human fetus may be a sensitive target for AFB(1) injury. Because AFB(1) requires metabolic activation to the reactive AFB(1)-8,9-exo-epoxide (AFBO) to exert its
Autor:
Adriana M. Doi, Michael K. Stoskopf
Publikováno v:
Journal of Aquatic Animal Health. 12:246-253
The kinetics of oxytetracycline (OTC) degradation in deionized water was studied under the influence of various environmental factors. The experiment was conducted with a solution of 10 μg aqueous OTC /mL in 600-mL glass beakers under controlled lab
Autor:
John R. Bucher, John C. Seely, Adriana M. Doi, Grace E. Kissling, James R. Hailey, Georgette D. Hill
Publikováno v:
Toxicologic pathology. 35(4)
Chemically induced renal neoplasms in male rats, developed coincident with α2u-globulin nephropathy, are not considered predictive of risk to humans by the International Agency for Research on Cancer (IARC) and the U.S. Environmental Protection Agen
Publikováno v:
Biochemical pharmacology. 67(11)
We are currently investigating the role of detoxification pathways in protecting against the sublethal effects of chemicals in largemouth bass (Micropterus salmoides). To this end, previous work in our laboratory indicated a remarkable ability of bas
Autor:
John R. Bucher, Sondra L. Grumbein, Roger A. Renne, Joseph K. Haseman, Adriana M. Doi, Billy J. Chou, Joseph H. Roycroft, Jeffrey A. Dill, Ronald A. Herbert, James R. Hailey, Rodney A. Miller
Publikováno v:
Toxicology. 199(1)
Propylene glycol mono-t-butyl ether (PGMBE) is used as a solvent in a variety of commercial applications. Male and female F344/N rats and B6C3F(1) mice were exposed to PGMBE by whole-body inhalation for 2 or 14 weeks (0, 75, 150, 300, 600, or 1200 pp