Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Adriana Limone"'
Autor:
Adriana Limone, Iolanda Veneruso, Antonella Izzo, Maurizio Renna, Raffaella Bonavita, Silvia Piscitelli, Gaetano Calì, Sergio De Nicola, Patrizia Riccio, Valeria D’Argenio, Antonio Lavecchia, Daniela Sarnataro
Publikováno v:
Cells, Vol 11, Iss 3, p 466 (2022)
To fight neurodegenerative diseases, several therapeutic strategies have been proposed that, to date, are either ineffective or at the early preclinical stages. Intracellular protein aggregates represent the cause of about 70% of neurodegenerative di
Externí odkaz:
https://doaj.org/article/c69d8e02f08c457bb35dbce20539ebfe
Publikováno v:
Journal of cellular physiology. 237(10)
Genetic studies support the amyloid cascade as the leading hypothesis for the pathogenesis of Alzheimer's disease (AD). Although significant efforts have been made in untangling the amyloid and other pathological events in AD, ongoing interventions f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75751d6312926752392447e07e183ec8
https://pubmed.ncbi.nlm.nih.gov/35994714
https://pubmed.ncbi.nlm.nih.gov/35994714
Autor:
Filomena Napolitano, Federica Di Maggio, Francesca Margheri, Alessandra Mocali, Nunzia Mollo, Giuseppina Minopoli, Daniela Sarnataro, Antaripa Bhattacharya, Valeria D'Argenio, Antonella Izzo, Antonio Lavecchia, Alessandra Lo Bianco, Nunzia Montuori, Adriana Limone
Publikováno v:
Journal of Personalized Medicine
Volume 10
Issue 4
Volume 10
Issue 4
Alzheimer&rsquo
s disease (AD) is a fatal neurodegenerative disorder caused by protein misfolding and aggregation, affecting brain function and causing dementia. Amyloid beta (A&beta
), a peptide deriving from amyloid precursor protein (APP
s disease (AD) is a fatal neurodegenerative disorder caused by protein misfolding and aggregation, affecting brain function and causing dementia. Amyloid beta (A&beta
), a peptide deriving from amyloid precursor protein (APP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e232e2046f653e070b5f41e89b208a
Autor:
Carmen Cerchia, Giuseppina Minopoli, Antonio Lavecchia, Filomena Napolitano, Daniela Sarnataro, Adriana Limone, Nunzia Montuori, Silvia Parisi, Antaripa Bhattacharya
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 5
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1738 (2020)
Volume 21
Issue 5
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1738 (2020)
Amyloid precursor protein (APP) is processed along both the nonamyloidogenic pathway preventing amyloid beta peptide (A&beta
) production and the amyloidogenic pathway, generating A&beta
whose accumulation characterizes Alzheimer&rsquo
) production and the amyloidogenic pathway, generating A&beta
whose accumulation characterizes Alzheimer&rsquo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55400696fded81626e98d172e81e290d