Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Adriana Ledeţi"'
Autor:
Andreea-Anda Alexa, Vasile-Nicolae Bercean, Sabina Elena Boncea, Adriana Ledeţi, Valentin Badea, Amalia Ridichie, Marilena Motoc, Ionuţ Ledeţi
Publikováno v:
Applied Sciences, Vol 14, Iss 14, p 6180 (2024)
In this paper, we present the synthesis, characterization and evaluation of antiproliferative activity for four compounds carrying the 4-amino-5-mercapto-1,2,4-triazol-3-yl scaffold. The synthesis of 1,n-bis-(4-amino-5-mercapto-1,2,4-triazol-3-yl) al
Externí odkaz:
https://doaj.org/article/97c85df380104e7084cc22ae408c9707
Autor:
Lenuţa-Maria Şuta, Amalia Ridichie, Adriana Ledeţi, Claudia Temereancă, Ionuţ Ledeţi, Delia Muntean, Matilda Rădulescu, Renata-Maria Văruţ, Claudia Watz, Florentin Crăineanu, Denisa Ivan, Gabriela Vlase, Lavinia Stelea
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 560 (2024)
Itraconazole is an antifungal agent included in the triazole pharmacological classification that belongs to the BCS class II, characterized by a low solubility in an aqueous medium (of 1 ng/mL, at neutral pH), which is frequently translated in a low
Externí odkaz:
https://doaj.org/article/0af0efcfa90a4d749bc5f1714b6a3efc
Autor:
Ionuţ Ledeţi, Ştefana Avram, Vasile Bercean, Gabriela Vlase, Titus Vlase, Adriana Ledeţi, Istvan Zupko, Marius Mioc, Lenuţa-Maria Şuta, Codruţa Şoica, Cristina Dehelean
Publikováno v:
Molecules, Vol 20, Iss 12, Pp 22691-22702 (2015)
Betulonic acid belongs to the pentacyclic triterpenic derivative class and can be obtained through the selective oxidation of betulin. In this study we set obtaining several functionalized derivatives of this compound by its condensation with several
Externí odkaz:
https://doaj.org/article/f4d698d484ff4c7a977808e9af99b24f
Autor:
Valentina Buda, Bianca Baul, Minodora Andor, Dana Emilia Man, Adriana Ledeţi, Gabriela Vlase, Titus Vlase, Corina Danciu, Petru Matusz, Francisc Peter, Ionuţ Ledeţi
Publikováno v:
Pharmaceutics, Vol 12, Iss 2, p 86 (2020)
The aim of this work was to assess the impact of an excipient in a pharmaceutical formulation containing candesartan cilexetil over the decomposition of the active pharmaceutical ingredient and to comparatively investigate the kinetics of degradation
Externí odkaz:
https://doaj.org/article/744fbf079a6847eda9b043de5c76674a
Autor:
Ledeţi, Bianca Baul, Adriana Ledeţi, Denisa Cîrcioban, Amalia Ridichie, Titus Vlase, Gabriela Vlase, Francisc Peter, Ionuţ
Publikováno v:
Processes; Volume 11; Issue 6; Pages: 1738
The stability of active pharmaceutical ingredients (APIs) and the corresponding pharmaceutical formulations are nowadays of great importance in pharmaceutical research and technology. The quality of an API or of finished pharmaceutical products (FPPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::b0a9d0a2b8cda5af9f1b1d7933d1301b
Publikováno v:
Journal of Thermal Analysis and Calorimetry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd55ebb7f690586ceeaf2eadb09361cb
https://doi.org/10.1007/s10973-023-12249-3
https://doi.org/10.1007/s10973-023-12249-3
Autor:
Ledeţi, Sebastian Simu, Adriana Ledeţi, Elena-Alina Moacă, Cornelia Păcurariu, Cristina Dehelean, Dan Navolan, Ionuţ
Publikováno v:
Processes; Volume 10; Issue 8; Pages: 1518
The present study reports the results obtained after the analysis of the thermal stability and decomposition kinetics of widely used synthetic derivative of estradiol, ethinylestradiol (EE), as a pure active pharmaceutical ingredient. As investigatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::2f720126126f1143c1f8320456ae68a1
Autor:
Ionuț-Mihai Tănase, Renata-Maria Văruţ, Adriana Ledeţi, Gabriela Vlase, Paul Barvinschi, Laura Sbârcea, Denisa Circioban, Ionuţ Ledeţi
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 142:1963-1976
Aripiprazole (ARP) is one of the newest antipsychotic drugs, exhibiting very low aqueous solubility and high lipophilicity. Considering the necessity of improvement of ARP physicochemical properties and its biopharmaceutical profile, cyclodextrin com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff9c3caff82c232a2a13b49bce4f5dce
https://doi.org/10.1007/s10973-020-09901-7
https://doi.org/10.1007/s10973-020-09901-7
Autor:
Denisa Circioban, Cristina Dehelean, Adriana Ledeţi, Gabriela Vlase, Ionuţ Ledeţi, Renata Văruț, Titus Vlase, Ioana Zinuca Pavel
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 141:1041-1051
The use of cyclodextrins as carrier molecules is currently highly researched since they can improve not only the apparent water solubility and bioavailability of lipophilic drugs, but can also enhance stability or mask unpleasant tastes and smells. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10c73405335f3466415911f08ff64193
https://doi.org/10.1007/s10973-020-09763-z
https://doi.org/10.1007/s10973-020-09763-z
Autor:
Anca Dragomirescu, Titus Vlase, Cezara Maria Muresan, Mihaela Cristea, Bianca Baul, Bożena Karolewicz, Dana Velimirovici, Mircea Stefanescu, Gabriela Vlase, Oana Stefanescu, Ionuţ Ledeţi, Dan-Simion Cipu, Adriana Ledeţi
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 138:2799-2806
This paper deals with the study of compatibility between antihyperlipidemic agent atorvastatin calcium trihydrate (ATV) and eight pharmaceutical excipients used in the development of solid dosage forms, namely citric acid, anhydrous lactose, magnesiu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5518f1083ca6ce305acad711684e6f2c
https://doi.org/10.1007/s10973-019-08798-1
https://doi.org/10.1007/s10973-019-08798-1