Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Adriana J. Michielsen"'
Autor:
Robert Geraghty, Aoife Maguire, Cara Dunne, Kieran Sheahan, Petra Martin, David Fennelly, Miriam Tosetto, James J. Phelan, Elizabeth J. Ryan, Jacintha O'Sullivan, Adriana J. Michielsen, Sinead Noonan, Margaret R. Dunne
Publikováno v:
Cancer Immunology, Immunotherapy
HLA-DR, an MHC class II molecule that mediates antigen presentation, is a favourable prognostic indicator in colorectal cancer (CRC). However, the dynamics and location of HLA-DR expression during CRC development are unclear. We aimed to define HLA-D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5ade1a943c52c260fbd186677ee6ae
http://europepmc.org/articles/PMC7347515
http://europepmc.org/articles/PMC7347515
Autor:
Adriana J Michielsen, Andrew E Hogan, Joseph Marry, Miriam Tosetto, Fionnuala Cox, John M Hyland, Kieran D Sheahan, Diarmuid P O'Donoghue, Hugh E Mulcahy, Elizabeth J Ryan, Jacintha N O'Sullivan
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27944 (2011)
Inflammatory mediators in the tumour microenvironment promote tumour growth, vascular development and enable evasion of anti-tumour immune responses, by disabling infiltrating dendritic cells. However, the constituents of the tumour microenvironment
Externí odkaz:
https://doaj.org/article/1fa55522fd5248f3ba6a2700a7b5a095
Autor:
Joanne Lysaght, John V. Reynolds, Gillian Moore, Eamon P. Breen, Adriana J. Michielsen, Katie E O' Sullivan, Ricardo Segurado, Jacintha O' Sullivan, Mary Clare Cathcart, Esther O' Regan
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 6
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1720 (2018)
Volume 19
Issue 6
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1720 (2018)
Signal transducers and activator of transcription (STAT)-3 is activated in cancers, where it promotes growth, inflammation, angiogenesis, and inhibits apoptosis. Tissue microarrays were generated using tissues from 154 patients, with oesophageal aden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9edd65cd5b883f134ab0bd56f058b7e
http://europepmc.org/articles/PMC6032321
http://europepmc.org/articles/PMC6032321
Publikováno v:
Oncoimmunology
We demonstrated that dendritic cell (DC) inhibition by tumor-conditioned media in the presence or absence of bevacizumab correlates with colorectal cancer patient survival. Monitoring the influence of the tumor microenvironment on infiltrating immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24aaeca0c9214ca8da8ddc22871dbce4
https://doi.org/10.4161/onci.21318
https://doi.org/10.4161/onci.21318
Publikováno v:
Oncoimmunology
Tumors inhibit dendritic cell maturation and function in order to evade host immunity. We showed that conditioned media from tumor explant tissue, taken from metastatic colorectal cancer patients, significantly inhibits maturation of dendritic cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cfb7711381624e6c32035223ecec67
http://europepmc.org/articles/PMC3429583
http://europepmc.org/articles/PMC3429583
Autor:
John Hyland, Miriam Tosetto, Adriana J. Michielsen, Sinead Noonan, Elizabeth J. Ryan, Petra Martin, Hugh Mulcahy, Jacintha O'Sullivan, Joseph Marry, Monika Biniecka, Aoife Maguire, David Fennelly, Diarmuid O'Donoghue, Kieran Sheahan
Publikováno v:
Molecular cancer therapeutics. 11(8)
Development of bevacizumab has improved survival in colorectal cancer, however, currently there are no biomarkers that predict response to bevacizumab and it is unknown how it influences the immune system in colorectal cancer patients. Dendritic cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586f0d61498ab4d0be6267610caf2e49
https://pubmed.ncbi.nlm.nih.gov/22675042
https://pubmed.ncbi.nlm.nih.gov/22675042
Autor:
John Hyland, Hugh Mulcahy, Joseph Marry, Elizabeth J. Ryan, Andrew E. Hogan, Jacintha O'Sullivan, Kieran Sheahan, Diarmuid O'Donoghue, Adriana J. Michielsen, Fionnuala Cox, Miriam Tosetto
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27944 (2011)
PLoS ONE
PLoS ONE
Inflammatory mediators in the tumour microenvironment promote tumour growth, vascular development and enable evasion of anti-tumour immune responses, by disabling infiltrating dendritic cells. However, the constituents of the tumour microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7500f6703df731dfd7aa0b58ac60cee
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22125641/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22125641/pdf/?tool=EBI
Autor:
Blathnaid Nolan, Diarmuid O'Donoghue, Aoibhlinn O'Toole, Jacintha O'Sullivan, Kieran Sheahan, John Hyland, Hugh Mulcahy, Miriam Tosetto, Adriana J. Michielsen, Glen A. Doherty, Elizabeth J. Ryan
Publikováno v:
Gastroenterology. 142:S-645
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7100e8b15c7c8b0a298782f4432ecdab
https://doi.org/10.1016/s0016-5085(12)62485-8
https://doi.org/10.1016/s0016-5085(12)62485-8
Autor:
Mary Clare Cathcart, Ronan Feighery, Jenny A. Watson, Margaret R. Dunne, Naoimh J. O’Farrell, Narayanasamy Ravi, John V. Reynolds, Brendan Doyle, Adriana J. Michielsen, Jacintha O'Sullivan, Elizabeth J. Ryan, Katie E. O’Sullivan, Elaine W. Kay
Publikováno v:
Cancer Immunology, Immunotherapy
Esophageal adenocarcinoma (EAC) is an aggressive cancer with poor prognosis, and incidence is increasing rapidly in the Western world. Measurement of immune markers has been shown to have prognostic significance in a growing number of cancers, but wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f8c7fa05fd84d9916f3686105a5afe