Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Adriana Ibarra Urizar"'
Autor:
Adriana Ibarra Urizar, Michala Prause, Lars Roed Ingerslev, Matthew Wortham, Yinghui Sui, Maike Sander, Kristine Williams, Romain Barrès, Martin R. Larsen, Gitte Lund Christensen, Nils Billestrup
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-16 (2023)
Summary Insufficient insulin secretion is a hallmark of type 2 diabetes and has been attributed to beta cell identity loss characterized by decreased expression of several key beta cell genes. The pro-inflammatory factor BMP-2 is upregulated in islet
Externí odkaz:
https://doaj.org/article/ff71f86b08274f6ea980a103f69cf1c4
Autor:
Andreas N. Madsen, Aurelie Vandenbeuch, Anthony P. Thompson, Andrew A. Pieper, Martin D. Cassell, Lucas D. BonDurant, Terry C. Yin, Birgitte Holst, Adriana Ibarra Urizar, Cecilia Ratner, Thomas P. J. Solomon, Matthew P. Gillum, Sue C. Kinnamon, Catherine B. Anderson, Stephanie von Holstein-Rathlou, Kristin E. Claflin, Lila Peltekian, Meghan C. Naber, Matthew J. Potthoff, Kristian Karstoft, Kamal Rahmouni
Publikováno v:
Cell Metabolism. 23(2):335-343
Summary The liver is an important integrator of nutrient metabolism, yet no liver-derived factors regulating nutrient preference or carbohydrate appetite have been identified. Here we show that the liver regulates carbohydrate intake through producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1604a6a3a5c0bc5a1496fbce4e26195
Autor:
Adriana Ibarra Urizar, Nils Billestrup, Josefine Friberg, Dan Ploug Christensen, Gitte Lund Christensen
Publikováno v:
Journal of Interferon & Cytokine Research. 36:20-29
The proinflammatory cytokines interleukin-1 beta (IL-1β) and interferon gamma (IFN-γ) play important roles in the progressive loss of beta-cell mass and function during development of both type 1 and type 2 diabetes. We have recently showed that bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b135e658424efedefb31d8c8aea8c2
https://doi.org/10.1089/jir.2014.0199
https://doi.org/10.1089/jir.2014.0199
Autor:
Nils Billestrup, Matthew Wortham, Michala Prause, Yinghui Sui, Peter Thams, Gitte Lund Christensen, Maike Sander, Adriana Ibarra Urizar
Publikováno v:
Molecular and Cellular Endocrinology. 496:110524
Decreased insulin secretory capacity in Type 2 diabetes mellitus is associated with beta-cell dedifferentiation and inflammation. We hypothesize that prolonged exposure of beta-cells to low concentrations of IL-1β induce beta-cell dedifferentiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e564771b1011ad747d575ebe797e94
https://doi.org/10.1016/j.mce.2019.110524
https://doi.org/10.1016/j.mce.2019.110524
Autor:
Michala Prause, Nils Billestrup, Thomas Mandrup-Poulsen, Joachim Størling, Adriana Ibarra Urizar, Lukas Adrian Berchtold, Mette Trauelsen
Publikováno v:
Molecular and cellular endocrinology. 420
Interleukin-1β (IL-1β) and interferon-γ (IFNγ) contribute to type 1 diabetes (T1D) by inducing β-cell death. Tumor necrosis factor (TNF) receptor-associated factor (TRAF) proteins are adaptors that transduce signaling from a variety of membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255a9a65d493e6243a67a6231d4ff9f2
https://pubmed.ncbi.nlm.nih.gov/26610752
https://pubmed.ncbi.nlm.nih.gov/26610752