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pro vyhledávání: '"Adriana Gielbert"'
Autor:
Adriana Gielbert, Jemma K Thorne, Jane M Plater, Leigh Thorne, Peter C Griffiths, Marion M Simmons, Claire A Cassar
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206505 (2018)
The prion hypothesis proposes a causal relationship between the misfolded prion protein (PrPSc) molecular entity and the disease transmissible spongiform encephalopathy (TSE). Variations in the conformation of PrPSc are associated with different form
Externí odkaz:
https://doaj.org/article/307ea2d9da1743bdaee95080f4edee84
Autor:
Liljana Petrovska, Martin J. Woodward, Yue Tang, Adriana Gielbert, Mary C Bagnall, Shaun Cawthraw
Publikováno v:
AIMS Microbiology. 3:885-898
Campylobacter jejuni is the major cause of bacterial gastroenteritis in man, while it is generally regarded as a commensal of the avian gut. Consumption and handling of contaminated poultry meat products are major risk factors for human infection. Th
Publikováno v:
Applied and Environmental Microbiology. 80:478-485
The animal gastrointestinal tract houses a large microbial community, the gut microbiota, that confers many benefits to its host, such as protection from pathogens and provision of essential metabolites. Metagenomic approaches have defined the chicke
Publikováno v:
Analytical Biochemistry. 436:36-44
Prions are proteins that can exist in two (or more) folding states, a normal or cellular form and a series of infectious or prion forms, which are prone to aggregate. The prion form can induce conversion of the cellular form and so transmit phenotypi
Publikováno v:
Cancer Letters. 284:15-20
The plasma pharmacokinetic characteristics of the chemopreventive isothiocyanate sulforaphane were determined in six human volunteers following single and repeated intake of raw broccoli. Initially, an analytical method utilising LC-MS/MS, capable of
Publikováno v:
Journal of Mass Spectrometry. 44:384-396
New forms of transmissible spongiform encephalopathy (TSE) continue to be identified, and consequently sensitive differential diagnosis is increasingly important both for the management of disease in humans and livestock and in providing confidence i
Autor:
Adriana Gielbert, Natalya Hanlon, Costas Ioannides, L. J. King, Maurice J. Sauer, Nick G. Coldham, Nikolai Kuhnert
Publikováno v:
British Journal of Nutrition. 99:559-564
Sulforaphane is a naturally occurring isothiocyanate with promising chemopreventive activity. An analytical method, utilising liquid chromatography-MS/MS, which allows the determination of sulforaphane in small volumes of rat plasma following exposur
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 2 (2015)
Frontiers in Molecular Biosciences, Vol 2 (2015)
Protein misfolding, protein aggregation and disruption to cellular proteostasis are key processes in the propagation of disease and, in some progressive neurodegenerative diseases of the central nervous system, the misfolded protein can act as a self
Autor:
Colin P. Churchward, R. A. J. Nicholas, Mercedes Domínguez, Roger D. Ayling, Rubén S. Rosales, Adriana Gielbert
Publikováno v:
The Journal of pharmacy and pharmacology. 67(3)
Objectives M ycoplasma mycoides subspecies capri is one of the causative agents of contagious agalactia in goats. The disease is characterised by mastitis, pneumonia, arthritis, keratitis and in acute cases septicaemia. No vaccine is currently availa
Autor:
J. G. Jacobs, Olivier Andreoletti, Adriana Gielbert, Maurice J. Sauer, Jan P. M. Langeveld, Thierry Baron, Yue Tang, Takashi Yokoyama
Publikováno v:
Journal of Immunological Methods
Journal of Immunological Methods, Elsevier, 2012, 380 (1-2), pp.30-9. ⟨10.1016/j.jim.2012.03.004⟩
Journal of Immunological Methods 380 (2012) 1-2
Journal of Immunological Methods, 380(1-2), 30-39
Journal of Immunological Methods, Elsevier, 2012, 380 (1-2), pp.30-9. ⟨10.1016/j.jim.2012.03.004⟩
Journal of Immunological Methods 380 (2012) 1-2
Journal of Immunological Methods, 380(1-2), 30-39
International audience; Prion diseases or transmissible spongiform encephalopathies (TSEs) in small ruminants are presented in many forms: classical scrapie, Nor98/atypical scrapie, CH1641 scrapie and bovine spongiform encephalopathy (BSE). We previo