Characterization and pharmacological properties of a novel multifunctional Kunitz inhibitor from Erythrina velutina seeds.

Autor: Richele J A Machado, Norberto K V Monteiro, Ludovico Migliolo, Osmar N Silva, Michele F S Pinto, Adeliana S Oliveira, Octávio L Franco, Sumika Kiyota, Marcelo P Bemquerer, Adriana F Uchoa, Ana H A Morais, Elizeu A Santos

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e63571 (2013)

Inhibitors of peptidases isolated from leguminous seeds have been studied for their pharmacological properties. The present study focused on purification, biochemical characterization and anti-inflammatory and anticoagulant evaluation of a novel Kuni

Externí odkaz: https://doaj.org/article/3d6afa934fdb40c7957a3ab751b00452

Vicilin from Anadenanthera colubrina Seeds: An alternative tool to combat Callosobruchus maculatus

Autor: Adeliana S. Oliveira, J.N. Araújo, Gabriella Silva Campos Carelli, D.A. Silva, Anderson Felipe Jácome de França, T.M.L. Amorim, Elizeu Antunes dos Santos, Ludovico Migliolo, Adriana F. Uchoa, Yago Queiroz dos Santos

Publikováno v: Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 9, Pp 5229-5237 (2021)

Highlights • Vicilins from Anadenanthera colubrina seeds (AcVs) interfered with the development of cowpea weevil (Callosobruchus maculatus) larvae. • AcVs present a strong effect at low concentrations on adult emergence (ED50 of 0.096%), on larva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0818d3b0054f17c9a570619bf82208
http://europepmc.org/articles/PMC8381016

From the application of active teaching methods to significant learning in Cellular and Molecular Biology: exploring possibilities with Problem Based Learning

Autor: Giulian César da Silva Sá, Elizeu Antunes dos Santos, Leidiane Barboza Silva, Adriana F. Uchoa

Publikováno v: Revista de Ensino de Bioquímica; v. 19, n. 1 (2021): REB (Jan-Jun); 1-15
Revista de Enseñanza de Bioquímica; v. 19, n. 1 (2021): REB (Jan-Jun); 1-15
Journal of Biochemistry Education; v. 19, n. 1 (2021): REB (Jan-Jun); 1-15
Revista de Ensino de Bioquímica
Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq)
instacron:SBBQM
Journal of Biochemistry Education, Vol 19, Iss 1, Pp 1-15 (2021)

Cellular and Molecular Biology contents are discussed in high school integrated to discipline Biology. However, the success of these reflections in higher education is compromised by the unavailability or restriction of the application of active teac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7420817a4a507cd5dc411e76f71be74e
http://bioquimica.org.br/revista/ojs/index.php/REB/article/view/928

Safety and potential functionality of nanoparticles loaded with a trypsin inhibitor isolated from tamarind seeds

Autor: Rafael Oliveira de Araújo Costa, Jaluza Luana Carvalho de Queiroz, Bruna Leal Lima Maciel, Ana Heloneida de Araújo Morais, Fabiana Maria Coimbra de Carvalho, Lorenzo Pastrana, Adriana F. Uchoa, Lídia Leonize Rodrigues Matias, Thaís Souza Passos, Catarina Gonçalves, Isabel R. Amado

Publikováno v: Future Foods, Vol 1, Iss, Pp 100001-(2020)

The trypsin inhibitor isolated from tamarind seeds (TTI) presents satietogenic and anti-inflammatory effects. In the present study, TTI encapsulation by nanoprecipitation in purified chitosan and whey protein isolate (ECW) was performed to maintain T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e2803bf10428de17a9247d59f12e0d
http://www.sciencedirect.com/science/article/pii/S2666833520300010

Gastroprotective and antielastase effects of protein inhibitors from Erythrina velutina seeds in an experimental ulcer model

Autor: Bruna Leal Lima Maciel, Christina da Silva Camillo, Norberto K.V. Monteiro, Ibson Lucas de Lyra, Elizeu Antunes dos Santos, Adriana F. Uchoa, Ana Heloneida de Araújo Morais, Vanessa Cristina Oliveira de Lima, Fabíola Patrícia da Silva Rufino, Adeliana S. Oliveira, Alexandre Coelho Serquiz, Richele J. A. Machado

Publikováno v: Biochemistry and Cell Biology. 95:243-250

Trypsin and chymotrypsin inhibitors from Erythrina velutina seeds have been previously isolated by our group. In previous studies using a sepsis model, we demonstrated the antitumor and anti-inflammatory action of these compounds. This study aimed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c53e8972770b05da95dbb67aed56427
https://doi.org/10.1139/bcb-2016-0034