Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Adriana E. Sedeno-Cortes"'
Autor:
Danilo Dubocanin, Adriana E. Sedeno Cortes, Gabrielle A. Hartley, Jane Ranchalis, Aman Agarwal, Glennis A. Logsdon, Katherine M. Munson, Taylor Real, Benjamin J. Mallory, Evan E. Eichler, Rachel J. O’Neill, Andrew B. Stergachis
SummaryThe focal attachment of the kinetochore to the centromere core is essential for genome maintenance, yet the highly repetitive nature of human centromeres limits our understanding of their chromatin organization. We demonstrate that single-mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1aa59deac284e04e4692379fe8149a3
https://doi.org/10.1101/2023.04.20.537689
https://doi.org/10.1101/2023.04.20.537689
Autor:
Danilo Dubocanin, Adriana E. Sedeno Cortes, Jane Ranchalis, Taylor Real, Ben Mallory, Andrew B. Stergachis
Telomeres are essential for linear genomes, yet their repetitive DNA content and somatic variability has hindered attempts to delineate their chromatin architectures. We performed single-molecule chromatin fiber sequencing (Fiber-seq) on human cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::759e614011e576d73dcfdaa1ae7ad139
https://doi.org/10.1101/2022.05.09.491186
https://doi.org/10.1101/2022.05.09.491186
Autor:
Owen White, Kimberly A. Smith, Brian D. Aevermann, William J. Romanow, Joseph R. Ecker, Michael Tieu, Michael Hawrylycz, Sheng-Yong Niu, Brian R. Herb, Jacinta Lucero, Sten Linnarsson, Tanya L. Daigle, Christine S. Liu, Ed S. Lein, Boudewijn P. F. Lelieveldt, Zizhen Yao, Yang Eric Li, Stephan Fischer, Trygve E. Bakken, Jeremy A. Miller, C. Dirk Keene, Scott F. Owen, Wei Tian, Joshua Orvis, Nongluk Plongthongkum, Rosa Castanon, Megan Crow, Thomas Höllt, Bing Ren, Darren Bertagnolli, Weixiu Dong, Herman Tung, Baldur van Lew, Delissa McMillen, Bosiljka Tasic, Angeline Rivkin, Eran A. Mukamel, Nora Reed, Alexander Dobin, Chongyuan Luo, Patrick R. Hof, Nick Dee, Rongxin Fang, Kirsten Crichton, M. Margarita Behrens, Anna Bartlett, Renee Zhang, Olivier Poirion, Josef Sulc, Philip R. Nicovich, Rebecca D. Hodge, Evan Z. Macosko, Staci A. Sorensen, Dinh Diep, Thanh Pham, Songlin Ding, Richard H. Scheuermann, Jayaram Kancherla, Jeroen Eggermont, Seth A. Ament, Ronna Hertzano, Jeff Goldy, Christine Rimorin, Julia K. Osteen, Kimberly Siletti, Steven A. McCarroll, Hanqing Liu, C. Palmer, Saroja Somasundaram, Jonathan T. Ting, Jerold Chun, Xiaomeng Hou, Guoping Feng, Kun Zhang, Fenna M. Krienen, Blue B. Lake, Amy Torkelson, Hongkui Zeng, Sebastian Preissl, Christof Koch, Nikolas L. Jorstad, Andrew L. Ko, Héctor Corrada Bravo, Aviv Regev, Nikolai C. Dembrow, Kanan Lathia, Antonio Pinto-Duarte, Xinxin Wang, Lucas T. Graybuck, Melissa Goldman, Marmar Moussa, William J. Spain, Peter V. Kharchenko, Qiwen Hu, Adriana E. Sedeno-Cortes, Gregory D. Horwitz, Rachel A. Dalley, Anup Mahurkar, Brian E. Kalmbach, Andrew Aldridge, Jesse Gillis, Anna Marie Yanny, Joseph R. Nery, Tamara Casper, Fangming Xie, Matthew Kroll
Publikováno v:
Nature, 598(7879), 111-119. NATURE PORTFOLIO
Nature
Nature: international weekly journal of science, 598(7879)
Nature
Nature: international weekly journal of science, 598(7879)
The primary motor cortex (M1) is essential for voluntary fine-motor control and is functionally conserved across mammals1. Here, using high-throughput transcriptomic and epigenomic profiling of more than 450,000 single nuclei in humans, marmoset monk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec172c4ec74873eefac841febd1a5574
https://www.nature.com/articles/s41586-021-03465-8.pdf
https://www.nature.com/articles/s41586-021-03465-8.pdf
Autor:
Susan M. Sunkin, Qingzhong Ren, Michael Tieu, Fahimeh Baftizadeh, Kimberly A. Smith, Boaz P. Levi, Kanan Lathia, Olivia Fong, James Gray, Lucas T. Graybuck, Jeff Goldy, Bosiljka Tasic, Christine Rimorin, Thuc Nghi Nguyen, Kirsten Crichton, Josef Sulc, Songlin Ding, Darren Bertagnolli, Zizhen Yao, Hongkui Zeng, Delissa McMillen, Cindy T. J. van Velthoven, Katelyn Ward, Alexandra Glandon, Thanh Pham, Herman Tung, Amy Torkelson, Nick Dee, Nadiya V. Shapovalova, Stephanie Mok, Emma Garren, Matthew Kroll, Tamara Casper, Adriana E. Sedeno-Cortes, Daniel Hirschstein
SUMMARYThe isocortex and hippocampal formation are two major structures in the mammalian brain that play critical roles in perception, cognition, emotion and learning. Both structures contain multiple regions, for many of which the cellular compositi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653919e9a1531a38cf23c9a9c7ff9701
https://doi.org/10.1101/2020.03.30.015214
https://doi.org/10.1101/2020.03.30.015214
Autor:
James Gray, Adriana E. Sedeno-Cortes, Michael Tieu, Songlin Ding, Michael Hawrylycz, Herman Tung, Olivia Fong, Matthew Kroll, Stephanie Mok, Zizhen Yao, Darren Bertagnolli, Fahimeh Baftizadeh, Thanh Pham, Delissa McMillen, Thuc Nghi Nguyen, Hongkui Zeng, Tamara Casper, Katelyn Ward, Emma Garren, Kimberly A. Smith, Qingzhong Ren, Christine Rimorin, Jeff Goldy, Alexandra Glandon, Kanan Lathia, Lucas T. Graybuck, Amy Torkelson, Nick Dee, Nadiya V. Shapovalova, Susan M. Sunkin, Daniel Hirschstein, Bosiljka Tasic, Kirsten Crichton, Josef Sulc, Boaz P. Levi, Cindy T. J. van Velthoven
Publikováno v:
SSRN Electronic Journal.
The isocortex and hippocampal formation are two major structures in the mammalian brain that play critical roles in perception, cognition, emotion and learning. Using single-cell RNA-sequencing approaches, we profiled ~1.2 million cells covering all
Autor:
Zizhen Yao, Olivia Fong, Thanh Pham, Katelyn Ward, James Gray, Susan M. Sunkin, Stephanie Mok, Hongkui Zeng, Songlin Ding, Boaz P. Levi, Qingzhong Ren, Daniel Hirschstein, Emma Garren, Nick Dee, Megan Chiang, Fahimeh Baftizadeh, Christine Rimorin, Kanan Lathia, Herman Tung, Cindy T. J. van Velthoven, Darren Bertagnolli, Nadiya V. Shapovalova, Lucas T. Graybuck, Jeff Goldy, Michael Tieu, Delissa McMillen, Kimberly A. Smith, Michael Hawrylycz, Bosiljka Tasic, Amy Torkelson, Kirsten Crichton, Josef Sulc, Alexandra Glandon, Nathan W. Gouwens, Thuc Nghi Nguyen, Tamara Casper, Matthew Kroll, Adriana E. Sedeno-Cortes, Changkyu Lee
Publikováno v:
Cell
The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in perception, cognition, emotion, and learning. We profiled ∼1.3 million cells covering the entire adult mouse isocortex and HPF and derived a transcriptomic
Publikováno v:
GigaScience
The Gene Ontology (GO) is one of the most widely used resources in molecular and cellular biology, largely through the use of "enrichment analysis". Despite the high importance of GO, there has been limited appreciation that it changes over time and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bb7a71fe4af666c9ef5d436212131d
Publikováno v:
Trends in Genetics. 30:513-514
Gene-set analysis (GSA) (‘enrichment') is a popular approach for the interpretation of genome-wide association studies (GWASs). GSA is most commonly applied to the analysis of transcriptomes, but from the outset it has been considered useful for an