Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Adriana Ducatenzeiler"'
Autor:
Rowan Pentz, M. Florencia Iulita, Maya Mikutra-Cencora, Adriana Ducatenzeiler, David A. Bennett, A. Claudio Cuello
Publikováno v:
Neurobiology of Disease, Vol 148, Iss , Pp 105150- (2021)
Matrix metalloproteinase-3 (MMP-3) has been associated with risk of Alzheimer's disease (AD). In this study we introduce a novel role for MMP-3 in degrading nerve growth factor (NGF) in vivo and examine its mRNA and protein expression across the cont
Externí odkaz:
https://doaj.org/article/009e9b1effe449c7a4f89917294f334d
Autor:
M. Florencia Iulita, M. Beatriz Bistué Millón, Rowan Pentz, Lisi Flores Aguilar, Sonia Do Carmo, Simon Allard, Bernadeta Michalski, Edward N. Wilson, Adriana Ducatenzeiler, Martin A. Bruno, Margaret Fahnestock, A. Claudio Cuello
Publikováno v:
Neurobiology of Disease, Vol 108, Iss , Pp 307-323 (2017)
Evidence from human neuropathological studies indicates that the levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are compromised in Alzheimer's disease. However, the causes and temporal (pathology-de
Externí odkaz:
https://doaj.org/article/6c0c94eebe334f3fa038f02a235a8d3c
Autor:
Lisi Flores‐Aguilar, Hélène Hall, Chiara Orciani, Morgan K. Foret, Olivia Kovecses, Adriana Ducatenzeiler, A. Claudio Cuello
Publikováno v:
Neuropathology and applied neurobiologyREFERENCES. 48(6)
The locus coeruleus (LC) is the main source of noradrenaline (NA) in the mammalian brain and has been found to degenerate during the initial stages of Alzheimer's disease (AD). Recent studies indicate that at late stages of the amyloid pathology, LC-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8ef4dfecfcf4e56d2e8276c5c7d948
https://pubmed.ncbi.nlm.nih.gov/35822518
https://pubmed.ncbi.nlm.nih.gov/35822518
Autor:
M. Florencia Iulita, Rafael Blesa, Alberto Lleó, Juan Fortea, Rowan Pentz, A. Claudio Cuello, Adriana Ducatenzeiler, Laura Videla, Maria Carmona-Iragui, Bessy Benejam
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Alzheimer's & Dementia
Universitat Autònoma de Barcelona
Alzheimer's & Dementia
Altres ajuts: This work was also supported by the National Institutes of Health (R21AG056974 and R01AG061566 to JF); Departament de Salut de la Generalitat de Catalunya, Pla Estratègic de Recerca i Innovació en Salut (SLT002/16/00408 to AL); Fundac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899ed26a15b44b7e2d22faade0cb777d
https://doi.org/10.1002/alz.12229
https://doi.org/10.1002/alz.12229
Publikováno v:
Mol Psychiatry
The NGF metabolic pathway entails the proteins that mature pro-nerve growth factor (proNGF) to NGF and those that degrade NGF. Basal forebrain cholinergic neurons require NGF for maintenance of cholinergic phenotype, are critical for cognition, and d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b3ed29ef23016fca9cbc1b6374179e
https://europepmc.org/articles/PMC10194044/
https://europepmc.org/articles/PMC10194044/
Autor:
Simon Allard, Maria Florencia Iulita, Lisi Flores Aguilar, Do Carmo S, Lindsay A. Welikovitch, Adriana Ducatenzeiler, Edward N. Wilson, Morgan K. Foret, A.C. Cuello, Emmerson Jt, Hélène Hall, Adam R. Marks, D T Jia
Publikováno v:
Journal of Alzheimer's disease : JAD. 73(2)
Epidemiological, preclinical, and clinical studies have suggested a role for microdose lithium in reducing Alzheimer's disease (AD) risk by modulating key mechanisms associated with AD pathology. The novel microdose lithium formulation, NP03, has dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd2eccc81a2be1f9c9a63e337ee808c4
https://pubmed.ncbi.nlm.nih.gov/31868669
https://pubmed.ncbi.nlm.nih.gov/31868669
Autor:
Rowan Pentz, Gordon K. Wilcock, Palma Gubert, Adriana Ducatenzeiler, A. Claudio Cuello, M. Florencia Iulita, Sharon Christie, Lisi Flores Aguilar, Aravind Ganesh
Publikováno v:
Journal of Alzheimer's disease : JAD. 67(1)
Biomarker discovery is a major need for earlier dementia diagnosis. We evaluated a plasma signature of amyloid, metallo-proteinases (MMPs), and inflammatory markers in a cohort of at-risk individuals and individuals clinically diagnosed with probable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28dea36f40cf285763594d57d604db1
https://pubmed.ncbi.nlm.nih.gov/30636741
https://pubmed.ncbi.nlm.nih.gov/30636741
Autor:
A.C. Cuello, Maria Florencia Iulita, Palma Gubert, Adriana Ducatenzeiler, Abraham Fisher, Lisi Flores Aguilar, Hélène Hall
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's Association. 14(6)
Introduction AF710B (aka ANAVEX 3-71) is a novel selective allosteric M1 muscarinic and sigma-1 receptor agonist. In 3×Tg-AD mice, AF710B attenuates cognitive deficits and decreases Alzheimer-like hallmarks. We now report on the long-lasting disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f13948f1f4e9df1216c1c0aff2ee16
https://pubmed.ncbi.nlm.nih.gov/29291374
https://pubmed.ncbi.nlm.nih.gov/29291374
Autor:
Sonia Do Carmo, A. Claudio Cuello, M. Florencia Iulita, Tiffany Paradis, Adriana Ducatenzeiler, Jon Reed, Gogce Crynen, Fiona Crawford
Publikováno v:
Molecular neurobiology. 55(4)
The cerebral accumulation and cytotoxicity of amyloid beta (Aβ) is central to Alzheimer’s pathogenesis. However, little is known about how the amyloid pathology affects the global expression of brain proteins at different disease stages. In order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115f8890b44092542362194bcbefdd5c
https://pubmed.ncbi.nlm.nih.gov/28502044
https://pubmed.ncbi.nlm.nih.gov/28502044
Autor:
Luisa S.B. Pimentel, Simon Allard, A. Claudio Cuello, Sonia Do Carmo, M. Florencia Iulita, Adriana Ducatenzeiler, Cecilia E. Hanzel, Alexa Pichet-Binette
Publikováno v:
Neurobiology of Aging. 35:2249-2262
Chronic brain inflammation is associated with Alzheimer's disease (AD) and is classically attributed to amyloid plaque deposition. However, whether the amyloid pathology can trigger early inflammatory processes before plaque deposition remains a matt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a468b8fdb1a51c3fdcef89af21e58263
https://doi.org/10.1016/j.neurobiolaging.2014.03.026
https://doi.org/10.1016/j.neurobiolaging.2014.03.026