Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Adriana Drost"'
Autor:
Adriana Drost, Robert Möhle
Publikováno v:
Annals of the New York Academy of Sciences. 1266:63-67
A variety of G protein-coupled receptors (GPCRs) is expressed in hematopoietic stem and progenitor cells (HPCs), including the chemokine receptor CXCR4, the leukotriene receptor CysLT1, the sphingosine 1-phosphate receptor S1P1, the cannabinoid recep
Autor:
Robert Möhle, Tina Wiesner, Gabriele Seitz, Adriana Drost, Lothar Kanz, Andreas M. Boehmler, Lena Jaggy, Claudio Denzlinger
Publikováno v:
The Journal of Immunology. 182:6789-6798
Cytokines and chemokines control hematopoietic stem and progenitor cell (HPC) proliferation and trafficking. However, the role of nonpeptide mediators in the bone marrow microenvironment has remained elusive. Particularly CysLT1, a G protein-coupled
Autor:
Anne Sofie Zipfel, Mirjam Funk, Lothar Kanz, Andreas Boehmler, Adriana Drost, Xingkui Xue, Karoline Norz, Robert Möhle, Gabriele Seitz
Publikováno v:
Leukemialymphoma. 53(4)
The G protein-coupled receptor (GPCR) CXCR4 is involved in bone marrow tropism and survival of chronic lymphocytic leukemia (CLL) cells. The function of the GPCRs cysteinyl leukotriene receptor 1 (CysLT1) and CysLT2 remains elusive. Here we demonstra
Autor:
Simon Baumann, Sibylle Weng, Gerhard Feil, Arnulf Stenzl, Jochen Schäfer, Robert Möhle, Adriana Drost, Karl-Dietrich Sievert, Lothar Kanz
Publikováno v:
Annals of the New York Academy of Sciences. 1176
To explore a new treatment strategy for urinary incontinence, human bone marrow mesenchymal stem cells (MSC) of the first in vitro passage were exposed to 5-azacytidine (AZA) to induce myogenic differentiation, and cultured for a total of six passage
Publikováno v:
Annals of the New York Academy of Sciences. 1014
Neuroendocrine tumor (NET) cells of the gastroenteropancreatic system express a variety of voltage-operated Ca(2+) channels (VOCCs). In addition, NET cells release hormones and biogenic amines in distinct patterns, leading to typical hypersecretion s
Publikováno v:
Blood. 118:3392-3392
Abstract 3392 CD34+ hematopoietic stem- and progenitor cells (HPC) express high levels of the G protein-coupled receptors (GPCR) CXCR4 and CysLT1. In contrast to the established role of CXCR4 in stem cell homing, the function of CysLT1 in HPC remains
Publikováno v:
Blood. 116:3612-3612
Abstract 3612 The G Protein-coupled receptors (GPCRs) CysLT1 and CysLT2 are both expressed in peripheral blood mononuclear cells (PBMNC). Their ligands are inflammatory mediators of the cysteinyl leukotriene (cysLT) family and contribute, together wi
Publikováno v:
Blood. 114:2325-2325
Abstract 2325 Poster Board II-302 Leukocytes, including B cells, represent the physiological source of lipid mediators of the cysteinyl-leukotriene family. In malignant B cells, particularly in B-CLL, even higher levels of enzymes involved in leukotr
Autor:
Robert Möhle, Adriana Drost, Sabine Maurer, Karl-Dietrich Sievert, Arnulf Stenzl, Sibylle Weng, Jutta Krug, Jochen Schäfer, Simon Baumann, Gerhard Feil
Publikováno v:
The Journal of Urology. 181:681
INTRODUCTION AND OBJECTIVES: Mesenchymal stem cells (MSCs) have the capacity to differentiate into smooth and skeletal muscle cells. Thus, autologous MSCs might be an option for a functional treatment of urinary incontinence (UI). The aim was to stud
Publikováno v:
Blood. 112:1388-1388
CysLT1, which is expressed in several cell types during inflammation and allergy, and the homing related chemokine receptor CXCR4 both belong to the family of G protein-coupled receptors (GPCR). Similar to CXCR4, the cysteinyl-leukotriene receptor cy