Výsledky vyhledávání - "Adriana Zatterale"

Akademický článek

Re-definition and supporting evidence toward Fanconi Anemia as a mitochondrial disease: Prospects for new design in clinical management

Autor: Giovanni Pagano, Luca Tiano, Federico V. Pallardó, Alex Lyakhovich, Sudit S. Mukhopadhyay, Paolo Di Bartolomeo, Adriana Zatterale, Marco Trifuoggi

Publikováno v: Redox Biology, Vol 40, Iss , Pp 101860- (2021)

Fanconi anemia (FA) has been investigated since early studies based on two definitions, namely defective DNA repair and proinflammatory condition. The former definition has built up the grounds for FA diagnosis as excess sensitivity of patients’ ce

Externí odkaz: https://doaj.org/article/55d50f4637334980a22a44acdc76487c

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Akademický článek

Twenty years of the Italian Fanconi Anemia Registry: where we stand and what remains to be learned

Autor: Antonio M. Risitano, Serena Marotta, Rita Calzone, Francesco Grimaldi, Adriana Zatterale

Publikováno v: Haematologica, Vol 101, Iss 3 (2016)

The natural history of Fanconi anemia remains hard to establish because of its rarity and its heterogeneous clinical presentation; since 1994, the Italian Fanconi Anemia Registry has collected clinical, epidemiological and genetic data of Italian Fan

Externí odkaz: https://doaj.org/article/d8f05a0eb8194289a8b3dac4cb550f66

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Re-definition and supporting evidence toward Fanconi Anemia as a mitochondrial disease: Prospects for new design in clinical management

Autor: Luca Tiano, Adriana Zatterale, Paolo Di Bartolomeo, Federico V. Pallardó, Sudit S. Mukhopadhyay, Marco Trifuoggi, Giovanni Pagano, Alex Lyakhovich

Publikováno v: Redox Biology, Vol 40, Iss, Pp 101860-(2021)
Redox Biology
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c51ff3f58389459642beaa0e60f693
https://doi.org/10.1016/j.redox.2021.101860

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Bone marrow cell transcripts from Fanconi anaemia patients revealin vivoalterations in mitochondrial, redox and DNA repair pathways

Autor: Sandra Petrović, Luca Tiano, Giovanni Pagano, Beatriz Porto, Annarita Aiello Talamanca, Federico V. Pallardó, Giuseppe Castello, Marco d'Ischia, Adriana Zatterale

Publikováno v: European Journal of Haematology

Fanconi anaemia (FA) is a genetic cancer predisposition disorder associated with cytogenetic instability, bone marrow failure and a pleiotropic cellular phenotype, including low thresholds of responses to oxidative stress, cross-linking agents and se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f856c78ae22aac9a9a1e5e5ad57f79d
https://doi.org/10.1111/ejh.12131

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Glutathione levels in blood from ataxia telangiectasia patients suggest in vivo adaptive mechanisms to oxidative stress

Autor: Kaan Kavakli, Emilia Vuttariello, Paola Manini, Paolo Degan, Federico V. Pallardó, Giovanni Pagano, Rita Calzone, Simona Cavalieri, Alfredo Brusco, Ana Lloret, Maria Antonietta Pisanti, Marco d'Ischia, Adriana Zatterale

Publikováno v: Clinical Biochemistry. 40:666-670

Objective: To evaluate an in vivo pro-oxidant state in patients with ataxia telangiectasia (AT). Methods: A set of oxidative stress endpoints were measured in 9 AT homozygotes, 16 AT heterozygotes (parents) and 83 controls (grouped in age ranges as f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d2f421a5cae7100a5f8a3623469daa
https://doi.org/10.1016/j.clinbiochem.2007.03.013

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Oxidative stress as a multiple effector in Fanconi anaemia clinical phenotype

Autor: Federico V. Pallardó, Paolo Degan, Bruno Nobili, Hagop Youssoufian, Adriana Zatterale, Marco d'Ischia, Frank J. Kelly, Giovanni Pagano

Publikováno v: European Journal of Haematology. 75:93-100

Fanconi anaemia (FA) is a genetic disease characterised by bone marrow failure with excess risk of myelogenous leukaemia and solid tumours. A widely accepted notion in FA research invokes a deficiency of response to DNA damage as the fundamental basi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39f9290fd6bac15db3094f1cdd63b45
https://doi.org/10.1111/j.1600-0609.2005.00507.x

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In vivoprooxidant state in Werner syndrome (WS): Results from three WS patients and two WS heterozygotes

Autor: Christina Dunster, Emilia Vuttariello, Paolo Degan, Ana Lloret, Giovanni Pagano, Marco d'Ischia, Rita Calzone, Frank J. Kelly, Aldo Giudice, Michel Warnau, Yurdanur Kilinç, Paola Manini, Roberta Masella, Giuseppe Castello, Adriana Zatterale, Federico V. Pallardó

Publikováno v: Free Radical Research. 39:529-533

The hypothesis was tested that Werner syndrome (WS) phenotype might be associated with an in vivo prooxidant state. A set of redox-related endpoints were measured in three WS patients, two of their parents, and 99 controls within a study of some canc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30cf9f45f6f0da41a2937c7dccc0aab
https://doi.org/10.1080/10715760500092683

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Identification of 14 rare marker chromosomes and derivatives by spectral karyotyping in prenatal and postnatal diagnosis

Autor: Fortunato Lonardo, Alessia Colosimo, Paolo Guanciali-Franchi, Carmelo Laganà, Alessandra Turci, Donatella Fantasia, Giuseppe Calabrese, Luciano Cristini, Maria Michela Rinaldi, Andrea Simonelli, Adriana Zatterale, Elisena Morizio, Giuseppe Sabatino, Giandomenico Palka, Liborio Stuppia

Publikováno v: American Journal of Medical Genetics Part A. :144-148

Extra structurally abnormal chromosomes (ESACs) and cryptic rearrangements are often associated with mental retardation and phenotypic abnormalities. In some cases their characterisation, using standard cytogenetic techniques and fluorescence in situ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7279f615ad8ab5fe3e5df1f4770cc7a
https://doi.org/10.1002/ajmg.a.20691

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Oxidative Stress and Mitochondrial Dysfunction across Broad-Ranging Pathologies: Toward Mitochondria-Targeted Clinical Strategies

Autor: Marco d'Ischia, Maria Nicola Gadaleta, Giuseppe Castello, Sandra Petrović, Adriana Zatterale, Luca Tiano, Annarita Aiello Talamanca, Federico V. Pallardó, Mario D. Cordero, Giovanni Pagano

Publikováno v: Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2014 (2014)

Beyond the disorders recognized as mitochondrial diseases, abnormalities in function and/or ultrastructure of mitochondria have been reported in several unrelated pathologies. These encompass ageing, malformations, and a number of genetic or acquired

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf525348c0e5d02a4777389d1a4331c
http://europepmc.org/articles/PMC4024404

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Trisomy 8 in myelodysplasia and acute leukemia is constitutional in 15-20% of cases

Autor: Adriana Zatterale, Giovanni Amendola, Francesco Pasquali, Franco Locatelli, Fiorenza Aprili, Antonella Minelli, Fabrizio Vinante, Emanuela Maserati, Giuseppe Milone, Francesco Lo Curto, Franca Bernardi

Publikováno v: Genes, Chromosomes and Cancer. 33:93-97

The trisomy 8 found in malignancies may derive from a constitutional trisomy 8 mosaicism (CT8M), and in these cases the trisomy itself may be regarded as the first mutation in a multistep carcinogenetic process. To assess the frequency of CT8M in hem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0e9e4a97bc919a91b22f460965cd16
https://doi.org/10.1002/gcc.1214

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