Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Adriana, Migliorini"'
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/e30f06c2d4d647c78c688ddd7dd0ac6f
Autor:
Karin Hrovatin, Aimée Bastidas-Ponce, Mostafa Bakhti, Luke Zappia, Maren Büttner, Ciro Sallino, Michael Sterr, Anika Böttcher, Adriana Migliorini, Heiko Lickert, Fabian J. Theis
Multiple pancreatic islet single-cell RNA sequencing (scRNA-seq) datasets have been generated to study development, homeostasis, and diabetes. However, there is no consensus on cell states and pathways across conditions as well as the value of precli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c06fe0cc7eaed6a29f83358420bb9216
https://doi.org/10.1101/2022.12.22.521557
https://doi.org/10.1101/2022.12.22.521557
Publikováno v:
Cell Metab
Tremendous progress has been made over the last two decades in the field of pancreatic beta cell replacement therapy as a curative measure for diabetes. Transplantation studies have demonstrated therapeutic efficacy, and cGMP-grade cell products are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f700a1d7d54506ba3aea39e85ae272ff
https://pubmed.ncbi.nlm.nih.gov/33826915
https://pubmed.ncbi.nlm.nih.gov/33826915
Autor:
Adriana Migliorini, Heiko Lickert
Publikováno v:
Molecular Metabolism, Vol 4, Iss 5, Pp 365-366 (2015)
Externí odkaz:
https://doaj.org/article/e0d1b42039c349aea4ef69485d2b3e44
Autor:
Maciej Lech, Christoph Römmele, Onkar P Kulkarni, Heni Eka Susanti, Adriana Migliorini, Cecilia Garlanda, Alberto Mantovani, Hans-Joachim Anders
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20118 (2011)
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes. Both of these
Externí odkaz:
https://doaj.org/article/9469556dec2d4335af8a01a9372142bc
Publikováno v:
Diabetologia. 59:1838-1842
Pancreatic beta cells differ in terms of glucose responsiveness, insulin secretion and proliferative capacity; however, the molecular pathways that regulate this cellular heterogeneity are unknown. We have identified the Wnt-planar cell polarity (PCP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e53e656b1347fcc31a044ca5fb0ac7b
https://doi.org/10.1007/s00125-016-3949-9
https://doi.org/10.1007/s00125-016-3949-9
Publikováno v:
Physiology (Bethesda, Md.). 33(6)
In this review, we focus on the processes guiding human pancreas development and provide an update on methods to efficiently generate pancreatic progenitors (PPs) and β-like cells in vitro from human pluripotent stem cells (hPSCs). Furthermore, we a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a02a52d27eef69f5be0b8f3ac2fe95
https://pubmed.ncbi.nlm.nih.gov/30303772
https://pubmed.ncbi.nlm.nih.gov/30303772
Autor:
Charles Affourtit, Uma D. Kabra, Adriana Migliorini, Moritz Gegg, Stephen C. Woods, Heiko Lickert, Katrin Pfuhlmann, Olle Korsgren, Susanne Keipert, Matthias H. Tschöp, Paul T. Pfluger, Martin Jastroch, Daniel Lamp
Publikováno v:
Diabetes
In pancreatic β-cells, mitochondrial bioenergetics control glucose-stimulated insulin secretion. Mitochondrial dynamics are generally associated with quality control, maintaining the functionality of bioenergetics. By acute pharmacological inhibitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdaee6f136457e89f1af53563bdf945
https://pubmed.ncbi.nlm.nih.gov/28174288
https://pubmed.ncbi.nlm.nih.gov/28174288
Autor:
Adriana Migliorini, Martin Jastroch, Katrin Pfuhlmann, Daniel Lamp, Moritz Gegg, Heiko Lickert, Charles Affourtit, Matthias H. Tschöp, Paul T. Pfluger, Stephen C. Woods, Uma D. Kabra, Olle Korsgren, Susanne Keipert
Publikováno v:
Diabetes 66, 1247-1257 (2017)
In pancreatic β-cells, mitochondrial bioenergetics control glucose-stimulated insulin secretion. Mitochondrial dynamics are generally associated with quality control, maintaining the functionality of bioenergetics. By acute pharmacological inhibitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4ff358406b9cdf10254b2b245ad8e3
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=50653
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=50653
The Antiviral Cytokines IFN-α and IFN-β Modulate Parietal Epithelial Cells and Promote Podocyte Loss
Autor:
Costanza Sagrinati, Alexander Dietrich, Onkar O. Kulkarni, Jana Demleitner, Helen Liapis, Hans-Joachim Anders, Stuart J. Shankland, Maria Lucia Angelotti, Paola Romagnani, Anna Julie Peired, Adriana Migliorini, Lara Ballerini, Shrikant R. Mulay
Publikováno v:
The American Journal of Pathology. 183:431-440
Interferon (IFN)-α and IFN-β are the central regulators of antiviral immunity but little is known about their roles in viral glomerulonephritis (eg, HIV nephropathy). We hypothesized that IFN-α and IFN-β would trigger local inflammation and podoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::defeee7804ecae45648a0140c8816a20
https://doi.org/10.1016/j.ajpath.2013.04.017
https://doi.org/10.1016/j.ajpath.2013.04.017