Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Adrian-Iustin Georgevici"'
Autor:
Shuo Lian, Sivakkanan Loganathan, Tobias Mayer, Patricia Kraft, Alex Ali Sayour, Adrian-Iustin Georgevici, Gábor Veres, Matthias Karck, Gábor Szabó, Sevil Korkmaz-Icöz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Coronary artery bypass surgery can result in endothelial dysfunction due to ischemia/reperfusion (IR) injury. Previous studies have demonstrated that DuraGraft helps maintain endothelial integrity of saphenous vein grafts during ischemic con
Externí odkaz:
https://doaj.org/article/7d652448ea5d413c857f405cd69f4703
Autor:
Sevil Korkmaz-Icöz, Sophia Abulizi, Kunsheng Li, Brice Korkmaz, Adrian-Iustin Georgevici, Alex Ali Sayour, Sivakkanan Loganathan, Hansa Canoglu, Matthias Karck, Gábor Szabó
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe shortage of available donor hearts and the risk of ischemia/reperfusion injury restrict heart transplantation (HTX). Alpha-1-antitrypsin (AAT), a well-characterized inhibitor of neutrophil serine protease, is used in augmentation ther
Externí odkaz:
https://doaj.org/article/2cc51d6ce1aa434d9a3b49caceae847b
Autor:
Lars Saemann, Kristin Wächter, Adrian-Iustin Georgevici, Sabine Pohl, Fabio Hoorn, Gábor Veres, Sevil Korkmaz-Icöz, Matthias Karck, Andreas Simm, Gábor Szabó
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1261 (2024)
Donation after circulatory death (DCD) hearts are predominantly maintained by normothermic blood perfusion (NBP). Nevertheless, it was shown that hypothermic crystalloid perfusion (HCP) is superior to blood perfusion to recondition left ventricular (
Externí odkaz:
https://doaj.org/article/18b7a5f7d9284e7f870ce67e48a45504
Autor:
Sevil Korkmaz-Icöz, Marcel Schwär, Sivakkanan Loganathan, Kristin Wächter, Adrian-Iustin Georgevici, Patricia Kraft, Tobias Mayer, Andreas Simm, Matthias Karck, Gábor Szabó
Publikováno v:
Journal of Functional Foods, Vol 95, Iss , Pp 105187- (2022)
Ischemia/reperfusion (IR) injury affects harvested vascular grafts during coronary artery bypass surgery. We hypothesized that bread crust extract (BCE) protects vascular grafts from IR injury. Thoracic aortic rings from Wistar rats were mounted on o
Externí odkaz:
https://doaj.org/article/60ff250b77b14f2eb68ed89276f14d71
Autor:
Lars Saemann, Adrian-Iustin Georgevici, Fabio Hoorn, Nitin Gharpure, Gábor Veres, Sevil Korkmaz-Icöz, Matthias Karck, Andreas Simm, Folker Wenzel, Gábor Szabó
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11562 (2023)
The impact of the machine perfusion of donation after circulatory death (DCD) hearts with the novel Custodiol-N solution on diastolic and coronary microvascular dysfunction is unknown. Porcine DCD-hearts were maintained four hours by perfusion with n
Externí odkaz:
https://doaj.org/article/6ea23a1091214165a5e1e9ed069dcc5f
Autor:
Adrian-Iustin Georgevici, Theodoros Kyprianou, Jennifer Herzog-Niescery, Livia Procopiuc, Sivakkanan Loganathan, Thomas Peter Weber, Martin Bellgardt
Publikováno v:
Critical Care, Vol 25, Iss 1, Pp 1-9 (2021)
Abstract Background Intensive care unit (ICU) physicians have extended the minimum alveolar concentration (MAC) to deliver and monitor long-term volatile sedation in critically ill patients. There is limited evidence of MAC’s reliability in control
Externí odkaz:
https://doaj.org/article/54d32bae8b8b44778e97820c195e5a70
Autor:
Lars Saemann, Fabio Hoorn, Adrian-Iustin Georgevici, Sabine Pohl, Sevil Korkmaz-Icöz, Gábor Veres, Yuxing Guo, Matthias Karck, Andreas Simm, Folker Wenzel, Gábor Szabó
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2280 (2022)
Microvascular dysfunction (MVD) in cardiac allografts is associated with an impaired endothelial function in the coronary microvasculature. Ischemia/reperfusion injury (IRI) deteriorates endothelial function. Hearts donated after circulatory death (D
Externí odkaz:
https://doaj.org/article/12aa984ac2a14dd1bba824f5d82b8d9a
Autor:
Sevil Korkmaz-Icöz, Cenk Kocer, Alex A. Sayour, Patricia Kraft, Mona I. Benker, Sophia Abulizi, Adrian-Iustin Georgevici, Paige Brlecic, Tamás Radovits, Sivakkanan Loganathan, Matthias Karck, Gábor Szabó
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 7774 (2021)
Vascular ischemia/reperfusion injury (IRI) contributes to graft failure and adverse clinical outcomes following coronary artery bypass grafting. Sodium-glucose-cotransporter (SGLT)-2-inhibitors have been shown to protect against myocardial IRI, irres
Externí odkaz:
https://doaj.org/article/d0e8bc37719b4c0190374222e3a66aca
Autor:
Martin Bellgardt, Adrian Iustin Georgevici, Mitja Klutzny, Dominik Drees, Andreas Meiser, Philipp Gude, Heike Vogelsang, Thomas Peter Weber, Jennifer Herzog-Niescery
Publikováno v:
Annals of Intensive Care, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract Background The MIRUS™ (TIM, Koblenz, Germany) is an electronical gas delivery system, which offers an automated MAC (minimal alveolar concentration)-driven application of isoflurane, sevoflurane, or desflurane, and can be used for sedation
Externí odkaz:
https://doaj.org/article/290c60bb35ae41049ba171c04b24eb05
Autor:
Thomas Weber, Vladimir Vinnikov, Jennifer Herzog-Niescery, Dominik Drees, Adrian Iustin Georgevici, Andreas Meiser, Martin Bellgardt, Livia Procopiuc
Publikováno v:
Journal of Clinical Monitoring and Computing. 36:169-177
To identify the better volatile anaesthetic delivery system in an intensive care setting, we compared the circle breathing system and two models of reflection systems (AnaConDa™ with a dead space of 100 ml (ACD-100) or 50 ml (ACD-50)). These system