Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Adrian-Bogdan Tigu"'
Autor:
Ciprian Tomuleasa, Adrian-Bogdan Tigu, Raluca Munteanu, Cristian-Silviu Moldovan, David Kegyes, Anca Onaciu, Diana Gulei, Gabriel Ghiaur, Hermann Einsele, Carlo M. Croce
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-51 (2024)
Abstract Receptor tyrosine kinases (RTKs), a category of transmembrane receptors, have gained significant clinical attention in oncology due to their central role in cancer pathogenesis. Genetic alterations, including mutations, amplifications, and o
Externí odkaz:
https://doaj.org/article/0776fe4bbdb94fc08ad9c64a0cef2914
Autor:
Ciprian Cucoreanu, Adrian-Bogdan Tigu, Madalina Nistor, Radu-Cristian Moldovan, Ioana-Ecaterina Pralea, Maria Iacobescu, Cristina-Adela Iuga, Robert Szabo, George-Calin Dindelegan, Constatin Ciuce
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 7430-7446 (2024)
Obesity is marked by excessive fat accumulation in the adipose tissue, which disrupts metabolic processes and causes chronic systemic inflammation. Commonly, body mass index (BMI) is used to assess obesity-related risks, predicting potential metaboli
Externí odkaz:
https://doaj.org/article/543982f3bc81404e8d86c126cba96f97
Autor:
Ciprian Cucoreanu, Ximena Maria Muresan, Adrian-Bogdan Tigu, Madalina Nistor, Radu-Cristian Moldovan, Ioana-Ecaterina Pralea, Maria Iacobescu, Cristina-Adela Iuga, Catalin Constantinescu, George-Calin Dindelegan, Constatin Ciuce
Publikováno v:
Reports, Vol 7, Iss 3, p 74 (2024)
In the last few decades, obesity played a pivotal role by having a high impact on global economic and health systems due to its associated diseases, with cardiovascular, respiratory, musculoskeletal, oncological, mental, and social implications. One
Externí odkaz:
https://doaj.org/article/40990e070ba546638e6e0c923545f494
Autor:
Adrian-Bogdan Tigu, Anamaria Bancos
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 11, Pp 8974-8988 (2023)
Peripheral T-cell lymphomas (PTCLs) are a group of diseases with a low incidence, high degree of heterogeneity, and a dismal prognosis in most cases. Because of the low incidence of these diseases, there have been few therapeutic novelties developed
Externí odkaz:
https://doaj.org/article/630e4cabb03844cfbd1ab611b0af5892
Autor:
Dragos Apostu, Daniel Oltean-Dan, Alexandru Mester, Andrei Maxim, Adrian Bogdan Tigu, Horea Rares Ciprian Benea, Dan Cosma, Doina Piciu
Publikováno v:
Applied Sciences, Vol 12, Iss 16, p 8054 (2022)
Background and Objectives: Cementless total hip arthroplasty leads to an early periprosthetic bone loss, which can impair the osseointegration process and lead to a femoral implant migration during early weight-bearing. An altered osseointegration pr
Externí odkaz:
https://doaj.org/article/8b3dca77b8f04c0eb959f490c206c07c
Autor:
Adrian Bartos, Ioana Iancu, Lidia Ciobanu, Anca Onaciu, Cristian Moldovan, Alin Moldovan, Radu Cristian Moldovan, Adrian Bogdan Tigu, Gabriela Fabiola Stiufiuc, Valentin Toma, Cornel Iancu, Nadim Al Hajjar, Rares Ionut Stiufiuc
Publikováno v:
Nanomaterials, Vol 12, Iss 16, p 2833 (2022)
Sorafenib is a multikinase inhibitor that has received increasing attention due to its high efficacy in hepatocellular carcinoma treatment. However, its poor pharmacokinetic properties (limited water solubility, rapid elimination, and metabolism) sti
Externí odkaz:
https://doaj.org/article/49dd8d3c316244bdb1c2cd15ba6361b0
Autor:
Cristian Silviu Moldovan, Anca Onaciu, Valentin Toma, Radu Marginean, Alin Moldovan, Adrian Bogdan Tigu, Gabriela Fabiola Stiufiuc, Constantin Mihai Lucaciu, Rares Ionut Stiufiuc
Publikováno v:
Pharmaceutics, Vol 13, Iss 10, p 1556 (2021)
Background: Cytochrome c (Cyt c) is a key biomarker for early apoptosis, and many methods were designed to detect its release from mitochondria. For a proper evaluation of these programed cell death mechanisms, fluorescent nanoparticles are excellent
Externí odkaz:
https://doaj.org/article/9358430e3c6d4e50ad17fd4d58a4284d
Autor:
Cornelia Braicu, Ioana Berindan-Neagoe, Alina-Andreea Zimta, Oana Zanoaga, Anupam Bishayee, Kaitlyn L. Kilpatrick, Adrian Bogdan Tigu, Seyed Mohammad Nabavi
Publikováno v:
Seminars in Cancer Biology. 80:218-236
Due to the high number of annual cancer-related deaths, and the economic burden that this malignancy affects today's society, the study of compounds isolated from natural sources should be encouraged. Most cancers are the result of a combined effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca126e31be46de2e0c1b1d4068269164
https://doi.org/10.1016/j.semcancer.2020.05.015
https://doi.org/10.1016/j.semcancer.2020.05.015
Autor:
Alexandru Leonard Alexa, Ancuta Jurj, Ciprian Tomuleasa, Adrian Bogdan Tigu, Raluca-Miorita Hategan, Daniela Ionescu
Publikováno v:
Current Issues in Molecular Biology; Volume 45; Issue 1; Pages: 738-751
Background: Colorectal cancer is highly common and causes high mortality rates. Treatment for colorectal cancer is multidisciplinary, but in most cases the main option remains surgery. Intriguingly, in recent years, a number of studies have shown tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2f71d94057ea018ef6b66ca63b857e
Tyrosine kinase inhibitor (TKI) therapy is gaining attraction in cancer therapeutics due to the ubiquity of kinases in cell survival and differentiation. Great progress was made in the past years for identifying tyrosine kinases that can function as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c157725a592d9dbf0501a8da4e009a5
https://doi.org/10.21203/rs.3.rs-2314501/v1
https://doi.org/10.21203/rs.3.rs-2314501/v1
