Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Adrian Y. Tan"'
Autor:
Qizhou Lian, Kui Zhang, Zhao Zhang, Fuyu Duan, Liyan Guo, Weiren Luo, Bobo Wing-Yee Mok, Abhimanyu Thakur, Xiaoshan Ke, Pedram Motallebnejad, Vlad Nicolaescu, Jonathan Chen, Chui Yan Ma, Xiaoya Zhou, Shuo Han, Teng Han, Wei Zhang, Adrian Y. Tan, Tuo Zhang, Xing Wang, Dong Xu, Jenny Xiang, Aimin Xu, Can Liao, Fang-Ping Huang, Ya-Wen Chen, Jie Na, Glenn Randall, Hung-fat Tse, Zhiwei Chen, Yin Chen, Huanhuan Joyce Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Model systems to study SARS-CoV-2 infection are required to better understand the immune response. Here the authors use a lung and macrophage co-culture system by differentiation of human pluripotent stem cells to better understand the phenotype and
Externí odkaz:
https://doaj.org/article/9938f59e696a4a09b36d23579730178b
Autor:
Xuming Tang, Dongxiang Xue, Tuo Zhang, Benjamin E. Nilsson-Payant, Lucia Carrau, Xiaohua Duan, Miriam Gordillo, Adrian Y. Tan, Yunping Qiu, Jenny Xiang, Robert E. Schwartz, Benjamin R. tenOever, Todd Evans, Shuibing Chen
Publikováno v:
Nature Cell Biology. 25:381-389
COVID-19 is a systemic disease involving multiple organs. We previously established a platform to derive organoids and cells from human pluripotent stem cells to model SARS-CoV-2 infection and perform drug screens1,2. This provided insight into cellu
Publikováno v:
Cureus.
Autor:
Hanna Rennert, Brian D. Robinson, Adrian Y. Tan, Jon D. Blumenfeld, Ines Chicos, Steven P. Salvatore, Hanwen Bai, Sandip Kapur, Stavros Giannakopoulos, Lior Rennert, Martin R. Prince, Zhengmao Zhang, Irina Barash, Alber Michaeel, Andrew B. Ramnauth, Karen Larbi, Genyan Liu, Stuart W. Hughes
Publikováno v:
J Am Soc Nephrol
Background: Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by the development of multiple cysts in the kidneys. It is often caused by pathogenic mutations in PKD1 and PKD2 genes that encode polycystin protein
Autor:
Tiantian Zhang, George Zhang, Xiang Chen, Zhengming Chen, Adrian Y. Tan, Anthony Lin, Cheryl Zhang, Lisa K. Torres, Sandi Bajrami, Tuo Zhang, Guoan Zhang, Jenny Z. Xiang, Erika M. Hissong, Yao-Tseng Chen, Yi Li, Yi-Chieh Nancy Du
Publikováno v:
Cancer letters. 546
Low-dose carbon monoxide (CO) is under investigation in clinical trials to treat non-cancerous diseases and has an excellent safety profile. Due to early detection and cancer awareness, an increasing number of cancer patients are diagnosed at early s
Autor:
Charles M. Rice, Liang Deng, Adrian Y. Tan, Joseph M. Luna, J. Choi, Gregory Mazo, Jenny Y. Wang, Tuo Zhang, W. Yan, Jedd D. Wolchok, Anthony M. Rossi, N. Yang, Shuaitong Liu, Jenny Xiang, Taha Merghoub, Yuxiang Wang
SummaryIntratumoral (IT) delivery of immune-activating viruses can serve as an important strategy to turn “cold” tumors into “hot” tumors, resulting in overcoming resistance to immune checkpoint blockade (ICB). Modified vaccinia virus Ankara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c44cab35c00e45b72f1da0b008d63359
https://doi.org/10.1101/2021.10.31.466698
https://doi.org/10.1101/2021.10.31.466698
Autor:
Qizhou Lian, Kui Zhang, Zhao Zhang, Fuyu Duan, Liyan Guo, Weiren Luo, Bobo Wing-Yee Mok, Abhimanyu Thakur, Xiaoshan Ke, Pedram Motallebnejad, Vlad Nicolaescu, Jonathan Chen, Chui Yan Ma, Xiaoya Zhou, Shuo Han, Teng Han, Wei Zhang, Adrian Y. Tan, Tuo Zhang, Xing Wang, Dong Xu, Jenny Xiang, Aimin Xu, Can Liao, Fang-Ping Huang, Ya-Wen Chen, Jie Na, Glenn Randall, Hung-fat Tse, Zhiwei Chen, Yin Chen, Huanhuan Joyce Chen
Publikováno v:
Nature communications. 13(1)
Dysfunctional immune responses contribute critically to the progression of Coronavirus Disease-2019 (COVID-19), with macrophages as one of the main cell types involved. It is urgent to understand the interactions among permissive cells, macrophages,
Autor:
Jenny Xiang, Liang Deng, Adrian Y. Tan, Ning Yang, Jiahu Wang, Taha Merghoub, John Choi, Shuaitong Liu, Jedd D. Wolchok, Tuo Zhang, Yi Wang, Gregory Mazo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundOncolytic viruses are promising therapeutic agents for advanced cancers because of their ability to induce antitumor innate and adaptive immunity. Modified vaccinia virus Ankara (MVA) is an attenuated, replication-deficient poxvirus safe fo
Autor:
N. Yang, W. Yan, Jenny Xiang, Adrian Y. Tan, Liang Deng, Shuaitong Liu, Gregory Mazo, Joseph M. Luna, J. Choi, Taha Merghoub, Yuxiang Wang, J. Wang, Anthony M. Rossi, Charles M. Rice, Jedd D. Wolchok
Publikováno v:
Journal of Investigative Dermatology. 141:S121
Autor:
Daniel M. Levine, Warren O. Bobb, Adrian Y. Tan, Hanna Rennert, Thomas S. Parker, Jon D. Blumenfeld, Stephanie Donahue, Alber Michaeel, Genyan Liu
Publikováno v:
Gene. 550:131-135
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in two large genes, PKD1 and PKD2, but genetic testing is complicated by the large transcript sizes and the duplication of PKD1 exons 1–33 as six pseudogenes on chromosome