Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Adrian Wilkins"'
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28745 (2011)
Human and animal studies have revealed a strong association between periconceptional environmental factors, such as poor maternal diet, and an increased propensity for cardiovascular and metabolic disease in adult offspring. Previously, we reported c
Externí odkaz:
https://doaj.org/article/c1ec9f8e35064d35b525674dde25bb12
Autor:
Christopher Torrens, Adrian Wilkins, Jane K. Cleal, Felino R. Cagampang, Meei J. Seet, V. Hugh Perry, Adam J. Watkins, Judith J. Eckert, William P. Gray, Tom P. Fleming, Mark A. Hanson, Colm Cunningham, Clive Osmond
Publikováno v:
The Journal of Physiology. 586:2231-2244
Early embryonic development is known to be susceptible to maternal undernutrition, leading to a disease-related postnatal phenotype. To determine whether this sensitivity extended into oocyte development, we examined the effect of maternal normal pro
Autor:
Judith J. Eckert, Arthur E. Wild, V. Hugh Perry, Elizabeth Ursell, Bhavwanti Sheth, Clive Osmond, Thomas Papenbrock, Wing Yee Kwong, Rose Panton, Adam J. Watkins, Mark A. Hanson, Adrian Wilkins, Lisa J. Hollis, Colm Cunningham, Tom P. Fleming
Publikováno v:
Biology of Reproduction. 78:299-306
Poor maternal nutrition during pregnancy can alter postnatal phenotype and increase susceptibility to adult cardiovascular and metabolic diseases. However, underlying mechanisms are largely unknown. Here, we show that maternal low protein diet (LPD),
Mouse embryo culture induces changes in postnatal phenotype including raised systolic blood pressure
Autor:
Clive Osmond, Adrian Wilkins, Duncan Platt, Tom Papenbrock, Judith J. Eckert, Adam J. Watkins, Tom P. Fleming, Mark A. Hanson, Wing Yee Kwong
Publikováno v:
Proceedings of the National Academy of Sciences. 104:5449-5454
A key factor in the use of assisted reproductive technologies (ART) for diverse species is the safety of procedures for long-term health. By using a mouse model, we have investigated the effect of in vitro culture and embryo transfer (ET) of superovu
Autor:
Adrian Wilkins, Tom P. Fleming, Clive Osmond, Carol M. Warner, Martina Comiskey, Adam J. Watkins, Mark A. Hanson
Publikováno v:
The Journal of Physiology. 571:211-220
The Ped (preimplantation embryo development) gene, whose product is Qa-2 protein, is correlated with a faster rate of preimplantation development (Ped fast phenotype) in mice that express Qa-2 protein compared with mice with an absence of Qa-2 protei
Autor:
Clive Osmond, Adrian Wilkins, J. Neville Wright, Wing Yee Kwong, Tom P. Fleming, Mark S. Dear, Daniel J. Miller, Junlong Zhang
Publikováno v:
Molecular Reproduction and Development. 74:48-56
It has been shown previously that maternal low protein diet (LPD) throughout rat gestation altered hepatic gene expression and enzyme activities in offspring. Here, we investigate the effect of maternal LPD (9% casein vs. 18% control) exclusively dur
Autor:
Wing Yee Kwong, Irina Fesenko, Judith J. Eckert, Richard Porter, Tom P. Fleming, Adrian Wilkins, Daniel J. Miller, Elizabeth Ursell, Adam J. Watkins
Publikováno v:
Biology of Reproduction. 71:1046-1054
The preimplantation mammalian embryo from different species appears sensitive to the environment in which it develops, either in vitro or in vivo, for example, in response to culture conditions or maternal diet. This sensitivity may lead to long-term
Autor:
Adam J, Watkins, Elizabeth, Ursell, Rose, Panton, Thomas, Papenbrock, Lisa, Hollis, Colm, Cunningham, Adrian, Wilkins, V Hugh, Perry, Bhavwanti, Sheth, Wing Yee, Kwong, Judith J, Eckert, Arthur E, Wild, Mark A, Hanson, Clive, Osmond, Tom P, Fleming
Publikováno v:
Biology of reproduction. 78(2)
Poor maternal nutrition during pregnancy can alter postnatal phenotype and increase susceptibility to adult cardiovascular and metabolic diseases. However, underlying mechanisms are largely unknown. Here, we show that maternal low protein diet (LPD),
Autor:
Elizabeth Ursell, Adrian Wilkins, Tom P. Fleming, Fred W Anthony, Clive Osmond, Wing Yee Kwong, Daniel J. Miller, Arthur E. Wild
Publikováno v:
Reproduction (Cambridge, England). 132(2)
In our previous study, we have shown that maternal low protein diet (LPD, 9% casein vs 18% casein control) fed exclusively during the rat preimplantation period (0–4.25 day postcoitum) induced low birth weight, altered postnatal growth and hyperten
Autor:
Tom P, Fleming, Wing Yee, Kwong, Richard, Porter, Elizabeth, Ursell, Irina, Fesenko, Adrian, Wilkins, Daniel J, Miller, Adam J, Watkins, Judith J, Eckert
Publikováno v:
Biology of reproduction. 71(4)
The preimplantation mammalian embryo from different species appears sensitive to the environment in which it develops, either in vitro or in vivo, for example, in response to culture conditions or maternal diet. This sensitivity may lead to long-term