Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Adrian Tun Kyi"'
Autor:
Morris Nechama, Jeahoo Kwon, Shuo Wei, Adrian Tun-Kyi, Robert S. Welner, Iddo Z. Ben-Dov, Mohamed S. Arredouani, John M. Asara, Chun-Hau Chen, Cheng-Yu Tsai, Kyle F. Nelson, Koichi S. Kobayashi, Elliot Israel, Xiao Zhen Zhou, Linda K. Nicholson, Kun Ping Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/9b0bb45b90e24907906ca667d17685dc
Autor:
Morris Nechama, Jeahoo Kwon, Shuo Wei, Adrian Tun-Kyi, Robert S. Welner, Iddo Z. Ben-Dov, Mohamed S. Arredouani, John M. Asara, Chun-Hau Chen, Cheng-Yu Tsai, Kyle F. Nelson, Koichi S Kobayashi, Elliot Israel, Xiao Zhen Zhou, Linda K. Nicholson, Kun Ping Lu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Abstract Interleukin 33 (IL-33) is among the earliest-released cytokines in response to allergens that orchestrate type 2 immunity. The prolyl cis-trans isomerase PIN1 is known to induce cytokines for eosinophil survival and activation by stabilizing
Externí odkaz:
https://doaj.org/article/f59a26dd71a44b3c90785a69ce33bbf8
Autor:
Xiao Zhen Zhou, Adrian Tun Kyi, John M. Asara, Iddo Z. Ben-Dov, Elliot Israel, Koichi Kobayashi, Mohamed S. Arredouani, Linda K. Nicholson, Kun Ping Lu, Morris Nechama, Chun-Hau Chen, Jeahoo Kwon, Shuo Wei, Robert S. Welner, Kyle F. Nelson, Cheng-Yu Tsai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Nature Communications
Nature Communications
Interleukin 33 (IL-33) is among the earliest-released cytokines in response to allergens that orchestrate type 2 immunity. The prolyl cis-trans isomerase PIN1 is known to induce cytokines for eosinophil survival and activation by stabilizing cytokine
Autor:
Michael Nowak, Mohammed S Arredouani, Adrian Tun-Kyi, Ingo Schmidt-Wolf, Martin G Sanda, Steven P Balk, Mark A Exley
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11311 (2010)
Numerical and functional defects of invariant natural killer T cells (iNKT) have been documented in human and mouse cancers, resulting in a defect in IFN production in several malignancies. iNKT cells recognize glycolipids presented on CD1d molecules
Externí odkaz:
https://doaj.org/article/93aa2fff4c9f40ef9fa68fef02e3c611
Autor:
Katherine A. Fitzgerald, John M. Asara, Linda K. Nicholson, Tae Ho Lee, George C. Tsokos, Greg Finn, Adrian Tun-Kyi, Michael Nowak, Elliot Israel, Alexander I. Greenwood, Mark A. Exley, Kun Ping Lu, Xiaoxia Li
Publikováno v:
Nature immunology
Toll-like receptors (TLRs) shape innate and adaptive immunity to microorganisms. The enzyme IRAK1 transduces signals from TLRs, but mechanisms for its activation and regulation remain unknown. We found here that TLR7 and TLR9 activated the isomerase
Autor:
Christina Y. Soohoo, Tae Ho Lee, Martin Balastik, Lucia Pastorino, Greg Finn, Gerburg M. Wulf, Xiao Zhen Zhou, Kun Ping Lu, Adrian Tun-Kyi, Jormay Lim, Rong Shi
Publikováno v:
Nature Cell Biology. 11:97-105
The prolyl isomerase Pin1 acts in various cellular processes. It has now been implicated in telomere maintenance by regulating the stability of the telomere binding protein TRF1. Telomeres are essential for maintaining cellular proliferative capacity
Autor:
Leonardo Cavone, Francesca Prignano, Giulia Mariotti, Gianni Gerlini, Adrian Tun-Kyi, Lorenzo Borgognoni, Astrid Parenti, Roberto Caporale, Nicola Pimpinelli, Paola Di Gennaro, Alberto Chiarugi, Riccardo Saccardi
Publikováno v:
The Journal of Immunology. 181:2999-3008
IFN-alpha is a well-known agent for treatment of viral and malignant diseases. It has several modes of actions, including direct influence on the immune system. We investigated IFN-alpha effects on PBMC in terms of dendritic cell (DC) differentiation
Autor:
Onur Boyman, Ute Laggner, Antonin de Fougerolles, Curdin Conrad, Victor E. Kotelianski, Adrian Tun-Kyi, Frank O. Nestle, Humphrey Gardner, Giulia Tonel
Publikováno v:
Nature Medicine. 13:836-842
Psoriasis is a common T cell-mediated autoimmune inflammatory disease. We show that blocking the interaction of alpha1beta1 integrin (VLA-1) with collagen prevented accumulation of epidermal T cells and immunopathology of psoriasis. Alpha1beta1 integ
Autor:
Shoji Yamaoka, Masahiro Yamamoto, Naoki Yamamoto, Greg Finn, Adrian Tun-Kyi, Akihide Ryo, Kun Ping Lu, Tatsuya Saitoh, Takashi Fujita, Shizuo Akira
Publikováno v:
Nature Immunology. 7:598-605
Recognition of double-stranded RNA activates interferon-regulatory factor 3 (IRF3)-dependent expression of antiviral factors. Although the molecular mechanisms underlying the activation of IRF3 have been studied, the mechanisms by which IRF3 activity
Autor:
Michael Gombert, Bernhard Homey, Curdin Conrad, Adrian Tun-Kyi, Yong-Jun Liu, Frank O. Nestle, Michel Gilliet, Onur Boyman, Günter Burg
Publikováno v:
The Journal of Experimental Medicine
Psoriasis is one of the most common T cell-mediated autoimmune diseases in humans. Although a role for the innate immune system in driving the autoimmune T cell cascade has been proposed, its nature remains elusive. We show that plasmacytoid predendr