Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Adrian T. Monstad-Rios"'
Autor:
Claire J Watson, W Joyce Tang, Maria F Rojas, Imke A K Fiedler, Ernesto Morfin Montes de Oca, Andrea R Cronrath, Lulu K Callies, Avery Angell Swearer, Ali R Ahmed, Visali Sethuraman, Sumaya Addish, Gist H Farr, Arianna Ericka Gómez, Jyoti Rai, Adrian T Monstad-Rios, Edith M Gardiner, David Karasik, Lisa Maves, Bjorn Busse, Yi-Hsiang Hsu, Ronald Young Kwon
Publikováno v:
PLoS Genetics, Vol 18, Iss 11, p e1010496 (2022)
Bone and muscle are coupled through developmental, mechanical, paracrine, and autocrine signals. Genetic variants at the CPED1-WNT16 locus are dually associated with bone- and muscle-related traits. While Wnt16 is necessary for bone mass and strength
Externí odkaz:
https://doaj.org/article/5c1e0f2009e24bea8e2128b9e43705bc
Autor:
Matthew Hur, Charlotte A Gistelinck, Philippe Huber, Jane Lee, Marjorie H Thompson, Adrian T Monstad-Rios, Claire J Watson, Sarah K McMenamin, Andy Willaert, David M Parichy, Paul Coucke, Ronald Y Kwon
Publikováno v:
eLife, Vol 6 (2017)
Phenomics, which ideally involves in-depth phenotyping at the whole-organism scale, may enhance our functional understanding of genetic variation. Here, we demonstrate methods to profile hundreds of phenotypic measures comprised of morphological and
Externí odkaz:
https://doaj.org/article/ab3609646a2c49b8a29417dd94269866
Autor:
Claire J. Watson, W. Joyce Tang, Maria F. Rojas, Imke A.K. Fiedler, Ernesto Morfin Montes de Oca, Andrea R. Cronrath, Lulu K. Callies, Avery Angell Swearer, Ali R. Ahmed, Visali Sethuraman, Sumaya Addish, Gist H. Farr, Arianna E. Gomez, Jyoti Rai, Adrian T. Monstad-Rios, Edith M. Gardiner, David Karasik, Lisa Maves, Bjorn Busse, Yi-Hsiang Hsu, Ronald Young Kwon
Bone and muscle interact through developmental, mechanical, paracrine, and autocrine signals. Genetic variants at the CPED1-WNT16 locus are dually associated with bone- and muscle-related traits. While Wnt16 is necessary for bone mass and strength, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58cef41a6044d6d8325b1fc36c87fad2
https://doi.org/10.1101/2021.08.12.456120
https://doi.org/10.1101/2021.08.12.456120
Autor:
Ryoko Minowa, Mia J. Konjikusic, Adrian T. Monstad-Rios, Ronald Y. Kwon, Benjamin R. Troutwine, Lilianna Solnica-Krezel, Paul Gontarz, Diane S. Sepich, Ryan S. Gray
SummarySpine morphogenesis requires the integration of multiple musculoskeletal tissues with the nervous system. Cerebrospinal fluid (CSF) physiology is important for development and homeostasis of the central nervous system and its disruption has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688001703921e2b9cb145b922f99b4b9
Autor:
Adrian T. Monstad-Rios, Claire J. Watson, Charlotte Gistelinck, Andy Willaert, Yi-Hsiang Hsu, Paul Coucke, Rehaan M. Bhimani, Ronald Y. Kwon
Publikováno v:
Cell Syst
Summary Genetic mosaicism can manifest as spatially variable phenotypes that vary from site to site within an organism. Here, we use imaging-based phenomics to quantitate phenotypes at many sites within the axial skeleton of CRISPR-edited G0 zebrafis
Autor:
Paul Coucke, Claire J. Watson, Andy Willaert, Adrian T. Monstad-Rios, Ronald Y. Kwon, Yi-Hsiang Hsu, Rehaan M. Bhimani, Charlotte Gistelinck
Genetic mosaicism manifests as spatially variable phenotypes, whose detection and interpretation remains challenging. This study identifies biological factors influencing spatial phenotypic patterns in the skeletons of somatic mutant zebrafish, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df78bcb32f200b0fdd86da39cdad8be
Autor:
Paul Gontarz, Mia J. Konjikusic, Benjamin R. Troutwine, Diane S. Sepich, Ryan S. Gray, Ryoko Minowa, Adrian T. Monstad-Rios, Ronald Y. Kwon, Lilianna Solnica-Krezel
Publikováno v:
Current Biology. 30:2353-2362.e3
Summary Cerebrospinal fluid (CSF) physiology is important for the development and homeostasis of the central nervous system, and its disruption has been linked to scoliosis in zebrafish [ 1 , 2 ]. Suspended in the CSF is an extracellular structure ca
Autor:
Paul Coucke, Charlotte Gistelinck, Marjorie H Thompson, Adrian T. Monstad-Rios, Philippe Huber, Jane Lee, Claire J. Watson, Andy Willaert, David M. Parichy, Matthew Hur, Ronald Y. Kwon, Sarah K. McMenamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aaeedaf0f4cb9b3af1f1eb7746d2877
https://doi.org/10.7554/elife.26014.037
https://doi.org/10.7554/elife.26014.037
Phenotype-based small molecule screens in zebrafish embryos and larvae have been successful in accelerating pathway and therapeutic discovery for diverse biological processes. Yet, the application of chemical screens to adult physiologies has been re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83f68e320ee140704ffa04cccc2c19e
https://doi.org/10.1101/163469
https://doi.org/10.1101/163469
Autor:
Charlotte Gistelinck, Andy Willaert, Claire J. Watson, Philippe Huber, Jane Lee, Adrian T. Monstad-Rios, Matthew Hur, Ronald Y. Kwon, Marjorie H Thompson, Sarah K. McMenamin, David M. Parichy, Paul Coucke
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Phenomics, which ideally involves in-depth phenotyping at the whole-organism scale, may enhance our functional understanding of genetic variation. Here, we demonstrate methods to profile hundreds of measures comprised of morphological and densitometr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af18de4e1bebac0697a051ca58c913f2