Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Adrian She"'
Autor:
Zhaleh Safikhani, Petr Smirnov, Mark Freeman, Nehme El-Hachem, Adrian She, Quevedo Rene, Anna Goldenberg, Nicolai J. Birkbak, Christos Hatzis, Leming Shi, Andrew H. Beck, Hugo J.W.L. Aerts, John Quackenbush, Benjamin Haibe-Kains
Publikováno v:
F1000Research, Vol 5 (2017)
In 2013, we published a comparative analysis of mutation and gene expression profiles and drug sensitivity measurements for 15 drugs characterized in the 471 cancer cell lines screened in the Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer C
Externí odkaz:
https://doaj.org/article/f48c19254168419d95a74f28bfdb0d84
Autor:
Prasad Chaugule, Mrinal Kumar, Nutan Limaye, Chandra Kanta Mohapatra, Adrian She, Srikanth Srinivasan
Publikováno v:
Chaugule, P, Kumar, M, Limaye, N, Mohapatra, C K, She, A & Srinivasan, S 2023, ' Schur Polynomials Do Not Have Small Formulas If the Determinant does not ', Computational Complexity, vol. 32, no. 1, 3 . https://doi.org/10.1007/s00037-023-00236-x
Schur Polynomials are families of symmetric polynomialsthat have been classically studied in Combinatorics and Algebra alike.They play a central role in the study of symmetric functions, in Representationtheory Stanley (1999), in Schubert calculus Le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757e62c08019b4e172fa0235741806d6
https://pure.au.dk/portal/da/publications/schur-polynomials-do-not-have-small-formulas-if-the-determinant-does-not(95d7fde2-ce23-415a-b3cb-93117ea314e7).html
https://pure.au.dk/portal/da/publications/schur-polynomials-do-not-have-small-formulas-if-the-determinant-does-not(95d7fde2-ce23-415a-b3cb-93117ea314e7).html
Publikováno v:
computational complexity. 31
Autor:
Alewo Idoko-Akoh, Daniel H. Goldhill, Carol M. Sheppard, Dagmara Bialy, Jessica L. Quantrill, Ksenia Sukhova, Jonathan C. Brown, Samuel Richardson, Ciara Campbell, Lorna Taylor, Adrian Sherman, Salik Nazki, Jason S. Long, Michael A. Skinner, Holly Shelton, Helen M. Sang, Wendy S. Barclay, Mike J. McGrew
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Chickens genetically resistant to avian influenza could prevent future outbreaks. In chickens, influenza A virus (IAV) relies on host protein ANP32A. Here we use CRISPR/Cas9 to generate homozygous gene edited (GE) chickens containing two ANP
Externí odkaz:
https://doaj.org/article/7998dd1a4f034f389765c3544b67d16a
In 1995 Stanley introduced the chromatic symmetric function $X_G$ of a graph $G$, whose $e$-positivity and Schur-positivity has been of large interest. In this paper we study the relative $e$-positivity and Schur-positivity between connected graphs o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506bd17283a6031cc95e49ac90724484
We prove that the chromatic symmetric function of any $n$-vertex tree containing a vertex of degree $d\geq \log _2n +1$ is not $e$-positive, that is, not a positive linear combination of elementary symmetric functions. Generalizing this, we also prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297f2e3a1fd6b89a652d133aaf03f2e2
Autor:
Mark Freeman, Patrick Grossmann, Dong Wang, Zhaleh Safikhani, Adrian She, Mathieu Lupien, Anna Goldenberg, Nehme El-Hachem, Hugo J.W.L. Aerts, Benjamin Haibe-Kains, Petr Smirnov, Andrew H. Beck, Deena M.A. Gendoo, Heather M. Selby, Catharina Olsen
Publikováno v:
Bioinformatics. 32:1244-1246
Summary: Pharmacogenomics holds great promise for the development of biomarkers of drug response and the design of new therapeutic options, which are key challenges in precision medicine. However, such data are scattered and lack standards for effici
Autor:
Petr Smirnov, Mark Freeman, Anna Goldenberg, Quevedo Rene, Zhaleh Safikhani, Leming Shi, Benjamin Haibe-Kains, Andrew H. Beck, Adrian She, Nehme El-Hachem, Hugo J.W.L. Aerts, John Quackenbush, Nicolai Juul Birkbak, Christos Hatzis
Publikováno v:
F1000Research
Background: In 2012, two large pharmacogenomic studies, the Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Cell Line Encyclopedia (CCLE), were published, each reported gene expression data and measures of drug response for a large number of
Autor:
Sabiha Essack, John Bell, Douglas Burgoyne, Khalid Eljaaly, Wirat Tongrod, Thomas Markham, Adrian Shephard, Elsa López-Pintor
Publikováno v:
Antibiotics, Vol 12, Iss 6, p 957 (2023)
A misunderstanding of the mechanism of action and bacterial targets of antibiotics by consumers may drive inappropriate antibiotic use and antimicrobial resistance (AMR). Tackling AMR requires an in-depth understanding of consumer beliefs and misconc
Externí odkaz:
https://doaj.org/article/edc20777c99042169e4cf403b1f77144
Autor:
Tapasvi Modi, David Gervais, Stuart Smith, Julie Miller, Shaan Subramaniam, Konstantinos Thalassinos, Adrian Shepherd
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 3, Pp 747-758 (2021)
The manufacture of the UK Anthrax vaccine (AVP) focuses on the production of Protective Antigen (PA) from the Bacillus anthracis Sterne strain. Although used for decades, several of AVP’s fundamental properties are poorly understood, including its
Externí odkaz:
https://doaj.org/article/b0e998a7de564fcaaeeefd31fd3c0691