Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Adrian Saldanha"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 6, Iss 1, Pp 742-747 (2010)
We have developed a synthetic route for the preparation of a hybrid bisubstrate small molecule based on a nucleoside. A prototype compound was designed and docked into the catalytic domain of the AdSS enzyme bridging the region between the magnesium
Externí odkaz:
https://doaj.org/article/88e9a4926466487fb449e8e667b2ad13
Autor:
Menglin Chen, Zhengrong Zhu, Tom Wisniewski, Xiaoping Zhang, David G. McLaren, Adam Weinglass, S. Adrian Saldanha
Publikováno v:
SLAS Discovery, Vol 27, Iss 7, Pp 405-412 (2022)
Study of small molecule binding to live cells provides important information on the characterization of ligands pharmacologically. Here we developed and validated a label-free, liquid chromatography-mass spectrometry (LC-MS) based cell binding assay,
Externí odkaz:
https://doaj.org/article/692086835e5a4837a6ecf8d1a559ee73
Autor:
Daiqing Liao, Peter Hodder, William R. Roush, Brian K. Law, Haiching Ma, Kyla R. Geary, Jamie Planck, Sanjay Adrian Saldanha, Stephan C. Jahn, Lisa Y. Zhao, Yunfei Wang, Dawei Li, Jian Luo, Christie E. Pinello, Heng Yang
PDF file - 456K, Table S1: Growth inhibition of NCI-60 panel of cancer cell lines by L002 (NSC764414); Supplemental Figure 1: Distribution of hits in the primary potentiator screen ; Supplemental Figure 2: Hit distribution in the primary and counters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22351f262f9dbbb833e7643c6d358cfe
https://doi.org/10.1158/1535-7163.22499485.v1
https://doi.org/10.1158/1535-7163.22499485.v1
Autor:
Daiqing Liao, Peter Hodder, William R. Roush, Brian K. Law, Haiching Ma, Kyla R. Geary, Jamie Planck, Sanjay Adrian Saldanha, Stephan C. Jahn, Lisa Y. Zhao, Yunfei Wang, Dawei Li, Jian Luo, Christie E. Pinello, Heng Yang
Acetyltransferase p300 (KAT3B) plays key roles in signaling cascades that support cancer cell survival and sustained proliferation. Thus, p300 represents a potential anticancer therapeutic target. To discover novel anticancer agents that target p300,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3980a194a39cf67caa85dfa27e601d
https://doi.org/10.1158/1535-7163.c.6536161
https://doi.org/10.1158/1535-7163.c.6536161
ispartof: pages:394-399 ispartof: IFAC PAPERSONLINE vol:55 issue:16 pages:394-399 ispartof: 18th IFAC Workshop on Control Applications of Optimization (CAO) location:FRANCE, Gif sur Yvette date:18 Jul - 22 Jul 2022 status: published
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de65e48b032dab43eeaa5297dce3009
https://lirias.kuleuven.be/handle/20.500.12942/709800
https://lirias.kuleuven.be/handle/20.500.12942/709800
Autor:
McLaren, David G., Vinit Shah, Wisniewski, Thomas, Ghislain, Lucien, Liu, Chang, Zhang, Hui, S. Adrian Saldanha
Supplemental material, sj-pdf-6-jbx-10.1177_2472555220980696 for High-Throughput Mass Spectrometry for Hit Identification: Current Landscape and Future Perspectives by David G. McLaren, Vinit Shah, Thomas Wisniewski, Lucien Ghislain, Chang Liu, Hui Z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0067db91c13f98dc86b0db6092bc7f1f
Autor:
McLaren, David G., Vinit Shah, Wisniewski, Thomas, Ghislain, Lucien, Liu, Chang, Zhang, Hui, S. Adrian Saldanha
Supplemental material, sj-pdf-7-jbx-10.1177_2472555220980696 for High-Throughput Mass Spectrometry for Hit Identification: Current Landscape and Future Perspectives by David G. McLaren, Vinit Shah, Thomas Wisniewski, Lucien Ghislain, Chang Liu, Hui Z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6ba6e1a1a9e88d7d446378317cb1e7d
Autor:
McLaren, David G., Vinit Shah, Wisniewski, Thomas, Ghislain, Lucien, Liu, Chang, Zhang, Hui, S. Adrian Saldanha
Supplemental material, sj-pdf-2-jbx-10.1177_2472555220980696 for High-Throughput Mass Spectrometry for Hit Identification: Current Landscape and Future Perspectives by David G. McLaren, Vinit Shah, Thomas Wisniewski, Lucien Ghislain, Chang Liu, Hui Z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d611ad3969186f03719445ba189f263d
Autor:
McLaren, David G., Vinit Shah, Wisniewski, Thomas, Ghislain, Lucien, Liu, Chang, Zhang, Hui, S. Adrian Saldanha
Supplemental material, sj-pdf-4-jbx-10.1177_2472555220980696 for High-Throughput Mass Spectrometry for Hit Identification: Current Landscape and Future Perspectives by David G. McLaren, Vinit Shah, Thomas Wisniewski, Lucien Ghislain, Chang Liu, Hui Z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cfdcb7a56ebc4764ea83f563d1c8d29
Autor:
McLaren, David G., Vinit Shah, Wisniewski, Thomas, Ghislain, Lucien, Liu, Chang, Zhang, Hui, S. Adrian Saldanha
Supplemental material, sj-pdf-3-jbx-10.1177_2472555220980696 for High-Throughput Mass Spectrometry for Hit Identification: Current Landscape and Future Perspectives by David G. McLaren, Vinit Shah, Thomas Wisniewski, Lucien Ghislain, Chang Liu, Hui Z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8f928d2b1860c6fa1c048dfe13df313