Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Adrian Robins"'
Autor:
Sonali Singh, Helen Barr, Yi-Chia Liu, Adrian Robins, Stephan Heeb, Paul Williams, Andrew Fogarty, Miguel Cámara, Luisa Martínez-Pomares
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117447 (2015)
Pseudomonas aeruginosa is an opportunistic pathogen that can cause severe infections at compromised epithelial surfaces, such those found in burns, wounds, and in lungs damaged by mechanical ventilation or recurrent infections, particularly in cystic
Externí odkaz:
https://doaj.org/article/4449efe659fe4be89321cd9fa91b1452
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74452 (2013)
C. difficile infection (CDI) is rarely reported in cystic fibrosis (CF) patients despite frequent hospitalisations and antibiotic usage. Conversely, the prevalence of CDI in inflammatory bowel disease (IBD) has received increased attention. We invest
Externí odkaz:
https://doaj.org/article/ed6c53fd050a4a7584906c6e56d1eb22
Autor:
Angela Midgley, Manjit Braitch, Mihailo Nebozhyn, R. Adrian Robins, Cris S. Constantinescu, Deena Barakat, Susan C. Fox, Louise C. Showe, Bruno Gran, Calen Nichols, Laura Edwards
Publikováno v:
Immunobiology
© 2020 Elsevier GmbH IL-23 is a potent stimulus for Th17 cells. These cells have a distinct developmental pathway from Th1 cells induced by IL-12 and are implicated in autoimmune and inflammatory disorders including multiple sclerosis (MS). TGF-β,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8e76b780ccaaa46ef1d41de25cdc2d
Publikováno v:
Clinical and Experimental Immunology
Summary The aim of our studies was to investigate the expression of Toll-like receptor (TLR)-2 and TLR-4 (and in some studies TLR-5) in myofibroblasts and small and large intestinal crypt epithelial cells from control patients and those affected by C
Autor:
Mohammad Ilyas, Karin B. Kindle, Nina Lane, Wakkas Fadhil, Adrian Robins, Abed M. Zaitoun, Darryl Jackson
Publikováno v:
International Journal of Experimental Pathology. 95:16-23
Colorectal cancers (CRC) are thought to have genetic instability in the form of either microsatellite instability (MSI) or chromosomal instability (CIN). Recently, tumours have been described without either MSI or CIN, that is, microsatellite and chr
Autor:
Tanya Monaghan, Herb F. Sewell, Katie Solomon, N. Gulati, Adrian Robins, Yashwant R. Mahida, N. Modi
Publikováno v:
Scandinavian Journal of Immunology. 74:264-271
Colitis due to Clostridium difficile infection is mediated by secreted toxins A and B and is characterized by infiltration by cells from the systemic circulation. The aim of our study was to investigate interactions between fluorescently labelled tox
Autor:
Julian Skoyles, Arvind V Singh, Ian M. Mitchell, Mya Baker, Joan Parton, Rajeshwara Krishna Prasad Adluri, Adrian Robins
Publikováno v:
The Heart Surgery Forum. 13:E353-E361
Background: Surgical trauma, exposure to an external circuit, and reduced organ perfusion contribute to the systemic inflammatory response following cardiopulmonary bypass (CPB). Reduced splanchnic perfusion causes disruption of the gastrointestinal
Autor:
Arvind V Singh, Adrian Robins, Rajeshwara Krishna Prasad Adluri, Ian M. Mitchell, Mya Baker, Tony Hitch, Julian Skoyles
Publikováno v:
Perfusion. 25:293-303
Reduced organ perfusion during cardiopulmonary bypass (CPB) is responsible for morbidity associated with cardiac surgery. Non-pulsatile flow and hypothermia during CPB have been shown to cause reduced perfusion. During CPB, cardiac output is directly
Publikováno v:
Clinical Science. 119:75-86
COPD (chronic obstructive pulmonary disease) is an inflammatory disorder of the airways, which is associated with irreversible airway obstruction. The pathological hallmarks of COPD are destruction of the lung parenchyma (pulmonary emphysema), inflam
Autor:
Lucy C. Fairclough, Farouk Shakib, Amal Hasan, Herb F. Sewell, Adrian Robins, Amir M. Ghaemmaghami
Publikováno v:
Immunobiology. 214:2-16
Dendritic cells are a major source of extracellular thiols needed for T cell activation, a process in which CD40-mediated stimulation plays a pivotal role. The Dermatophagoides pteronyssinus group 1 mite allergen (Der p 1) has previously been shown t