Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Adrian P. Duval"'
Publikováno v:
Cancers, Vol 11, Iss 10, p 1453 (2019)
Cancers
Volume 11
Issue 10
Cancers, vol. 11, no. 10
Cancers
Volume 11
Issue 10
Cancers, vol. 11, no. 10
Sorafenib is the first developed systemic treatment for advanced forms of hepatocellular carcinoma, which constitutes the most frequent form of primary liver cancers and is a major global health burden. Although statistically significant, the positiv
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2225 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Cancer cachexia affects most patients with advanced forms of cancers. It is mainly characterized by weight loss, due to muscle and adipose mass depletion. As cachexia is associated with increased morbidity and mortality in cancer patients, identifyin
Autor:
Seraina Faes, Catherine Pythoud, Janine Horlbeck, Nicolas Demartines, Nicolo Riggi, Emilie Uldry, Tania Santoro, Igor Letovanec, Olivier Dormond, Jean-Christophe Stehle, Adrian P. Duval, Anne Planche
Publikováno v:
Molecular Cancer
Molecular cancer, vol. 15, no. 1, pp. 78
Europe PubMed Central
Molecular cancer, vol. 15, no. 1, pp. 78
Europe PubMed Central
Background: Blocking the mechanistic target of rapamycin complex-1 (mTORC1) with chemical inhibitors such as rapamycin has shown limited clinical efficacy in cancer. The tumor microenvironment is characterized by an acidic pH which interferes with ca