Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Adrian Negrean"'
Autor:
Zhenrui Liao, Kevin C. Gonzalez, Deborah M. Li, Catalina M. Yang, Donald Holder, Natalie E. McClain, Guofeng Zhang, Stephen W. Evans, Mariya Chavarha, Jane Simko, Christopher D. Makinson, Michael Z. Lin, Attila Losonczy, Adrian Negrean
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Fast electrical signaling in dendrites is central to neural computations that support adaptive behaviors. Conventional techniques lack temporal and spatial resolution and the ability to track underlying membrane potential dynamics present ac
Externí odkaz:
https://doaj.org/article/1530b5838c934189b0b0e531262ffc58
Publikováno v:
J Neurosci
Synaptic inputs that target distal regions of neuronal dendrites can often generate local dendritic spikes that can amplify synaptic depolarization, induce synaptic plasticity, and enhance neuronal output. However, distal dendritic spikes are subject
Autor:
Attila Losonczy, Tristan Geiller, Sebastian V. Rolotti, Sadra Sadeh, Heike Blockus, Claudia Clopath, Adrian Negrean, Balázs Rózsa, Andrew J. Murray, Franck Polleux, Bert Vancura
Publikováno v:
Nature
Local circuit architecture facilitates the emergence of feature selectivity in the cerebral cortex1. In the hippocampus, it remains unknown whether local computations supported by specific connectivity motifs2 regulate the spatial receptive fields of
Autor:
Aina Badia-Soteras, Tim S. Heistek, Mandy S.J. Kater, Aline Mak, Adrian Negrean, Michel C. van den Oever, Huibert D. Mansvelder, Baljit S. Khakh, Rogier Min, August B. Smit, Mark H.G. Verheijen
Publikováno v:
Biological Psychiatry. Elsevier USA
Badia-Soteras, A, Heistek, T S, Kater, M S J, Mak, A, Negrean, A, van den Oever, M C, Mansvelder, H D, Khakh, B S, Min, R, Smit, A B & Verheijen, M H G 2023, ' Retraction of Astrocyte Leaflets From the Synapse Enhances Fear Memory ', Biological psychiatry, vol. 94, no. 3, pp. 226-238 . https://doi.org/10.1016/j.biopsych.2022.10.013
Badia-Soteras, A, Heistek, T S, Kater, M S J, Mak, A, Negrean, A, van den Oever, M C, Mansvelder, H D, Khakh, B S, Min, R, Smit, A B & Verheijen, M H G 2023, ' Retraction of Astrocyte Leaflets From the Synapse Enhances Fear Memory ', Biological Psychiatry, vol. 94, no. 3, pp. 226-238 . https://doi.org/10.1016/j.biopsych.2022.10.013
Biological psychiatry. Elsevier USA
Badia-Soteras, A, Heistek, T S, Kater, M S J, Mak, A, Negrean, A, van den Oever, M C, Mansvelder, H D, Khakh, B S, Min, R, Smit, A B & Verheijen, M H G 2023, ' Retraction of Astrocyte Leaflets From the Synapse Enhances Fear Memory ', Biological psychiatry, vol. 94, no. 3, pp. 226-238 . https://doi.org/10.1016/j.biopsych.2022.10.013
Badia-Soteras, A, Heistek, T S, Kater, M S J, Mak, A, Negrean, A, van den Oever, M C, Mansvelder, H D, Khakh, B S, Min, R, Smit, A B & Verheijen, M H G 2023, ' Retraction of Astrocyte Leaflets From the Synapse Enhances Fear Memory ', Biological Psychiatry, vol. 94, no. 3, pp. 226-238 . https://doi.org/10.1016/j.biopsych.2022.10.013
Biological psychiatry. Elsevier USA
BACKGROUND: The formation and retrieval of fear memories depends on orchestrated synaptic activity of neuronal ensembles within the hippocampus, and it is becoming increasingly evident that astrocytes residing in the environment of these synapses pla
Autor:
Justin K. O’Hare, Kevin C. Gonzalez, Stephanie A. Herrlinger, Yusuke Hirabayashi, Victoria L. Hewitt, Heike Blockus, Miklos Szoboszlay, Sebi V. Rolotti, Tristan C. Geiller, Adrian Negrean, Vikas Chelur, Franck Polleux, Attila Losonczy
Publikováno v:
Science. 375
Dendritic calcium signaling is central to neural plasticity mechanisms that allow animals to adapt to the environment. Intracellular calcium release (ICR) from the endoplasmic reticulum has long been thought to shape these mechanisms. However, ICR ha
Autor:
Aina Badia-Soteras, Tim S Heistek, Mandy S J Kater, Adrian Negrean, Huibert D Mansvelder, Baljit S Khakh, Rogier Min, August B Smit, Mark H G Verheijen
SummaryAstrocyte distal processes, known as leaflets or perisynaptic astrocyte processes (PAPs), fine-tune synaptic activity by clearing neurotransmitters and limiting extrasynaptic glutamate diffusion. While learning and memory depends on orchestrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8e00dbada5a4b8764d92782179565d8
https://doi.org/10.1101/2022.01.30.478393
https://doi.org/10.1101/2022.01.30.478393
Autor:
Sebi V. Rolotti, Mohsin S. Ahmed, Miklos Szoboszlay, Tristan Geiller, Adrian Negrean, Heike Blockus, Kevin C. Gonzalez, Fraser T. Sparks, Ana Sofia Solis Canales, Anna L. Tuttman, Darcy S. Peterka, Boris V. Zemelman, Franck Polleux, Attila Losonczy
Publikováno v:
Neuron
Hippocampal place cells underlie spatial navigation and memory. Remarkably, CA1 pyramidal neurons can form new place fields within a single trial by undergoing rapid plasticity. However, local feedback circuits likely restrict the rapid recruitment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d056af2e4686a2834213939dc88712a
https://europepmc.org/articles/PMC8897257/
https://europepmc.org/articles/PMC8897257/
Publikováno v:
Neuroscience
Much of our understanding of dendritic and synaptic physiology comes from in vitro experimentation, where the afforded mechanical stability and convenience of applying drugs allowed patch-clamping based recording techniques to investigate ion channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff7c58af295c9c1c67ae14674fa19ba
https://europepmc.org/articles/PMC9392867/
https://europepmc.org/articles/PMC9392867/
Autor:
Carl-Mikael Suomivuori, A. Reese, Mariya Chavarha, Peyman Golshani, Dadi Jiang, Song Eun Lee, M. Pang, Shan X. Wang, Dongqing Shi, Lagnajeet Pradhan, Michael Z. Lin, Attila Losonczy, Yuzhe Liu, Jiang Lan Fan, Jiannis Taxidis, B. Madruga, Adrian Negrean, Mark Plitt, Na Ji, Stephen W Evans, Lisa M. Giocomo, S. Su, Thomas R. Clandinin, S. C. Van Keulen, Jie Ding, C. D. Makinson, F.-J. Hwang, Ron O. Dror, Gang Zhang, G. G. Bi
Neuronal spiking activity is routinely recorded using genetically encoded calcium indicators (GECIs), but calcium imaging is limited in temporal resolution and does not report subthreshold voltage changes. Genetically encoded voltage indicators (GEVI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dea41976e39d352d34f3af3865428bc6
https://doi.org/10.1101/2021.10.21.465345
https://doi.org/10.1101/2021.10.21.465345
Autor:
Vikas Chelur, Justin K. O’Hare, Miklos Szoboszlay, Tristan Geiller, Sebi V. Rolotti, Heike Blockus, Victoria L. Hewitt, Attila Losonczy, Adrian Negrean, Yusuke Hirabayashi, Franck Polleux
Dendritic Ca2+ signaling is central to neural plasticity mechanisms allowing animals to adapt to the environment. Intracellular Ca2+ release (ICR) from endoplasmic reticulum has long been thought to shape these mechanisms. However, ICR has not been i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eb3ef84771835b62d329584cf2dff63
https://doi.org/10.1101/2021.09.27.460811
https://doi.org/10.1101/2021.09.27.460811