Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Adrian Muenscher"'
Autor:
Lara Bußmann, Simon Laban, Claus Wittekindt, Carmen Stromberger, Silke Tribius, Nikolaus Möckelmann, Arne Böttcher, Christian Stephan Betz, Jens Peter Klussmann, Volker Budach, Adrian Muenscher, Chia-Jung Busch
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background For loco-regionally advanced, but transorally resectable oropharyngeal cancer (OPSCC), the current standard of care includes surgical resection and risk-adapted adjuvant (chemo) radiotherapy, or definite chemoradiation with or wit
Externí odkaz:
https://doaj.org/article/58894626f2da4ac897449c686d2236d5
Autor:
Adrian Muenscher, Philippe Schafhausen, Henrike Barbara Zech, Nikolaus Moeckelmann, Mascha Binder, Arne Boettcher, Christian Stephan Betz, Chia-Jung Busch, Eik Vettorazzi, Carsten Bokemeyer
Publikováno v:
Future Oncology. 16:3035-3043
Locally advanced head and neck squamous cell carcinoma (LA-HNSCC) often requires postoperative chemoradiation with high risk of toxicity. Disease-free survival (DFS) after 2 years is approximately 70%. Combining nivolumab (N), a PD-1-inhibitor and ip
Autor:
Nikolaus Möckelmann, Simon Laban, Adrian Muenscher, Jens Peter Klussmann, Chia-Jung Busch, Christian Stephan Betz, Arne Böttcher, Claus Wittekindt, Carmen Stromberger, Silke Tribius, Volker Budach, Lara Bußmann
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Background For loco-regionally advanced, but transorally resectable oropharyngeal cancer (OPSCC), the current standard of care includes surgical resection and risk-adapted adjuvant (chemo) radiotherapy, or definite chemoradiation with or without salv
Autor:
Marco Blessmann, Cornelia Schroeder, Adrian Muenscher, Henning Hanken, Julie Cläre Nienstedt, Christina Pflug, Guido Sauter, Till S. Clauditz, Ronald Simon
Publikováno v:
Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 47(3)
Background Enhancer of zeste homolog 2 (EZH2), the catalytic subunit of the polycomb repressive complex 2, plays an important role in tumor development and progression by interacting with histone and non-histone proteins. EZH2 represents a putative t
Publikováno v:
Clinical oral investigations. 23(8)
Nucleotide excision repair protein expression has been claimed to be responsible for platinum-based chemotherapy resistance. ERCC1, XPF and XPA, core proteins in DNA repair, were evaluated regarding their prognostic value in patients with head and ne
Autor:
Rainald Knecht, Adrian Muenscher, Max Heiland, Christina Pflug, Till S. Clauditz, Marco Blessmann, Julie Cläre Nienstedt, Alexander Gröbe, Christoph Moebius, Ronald Simon, Guido Sauter
Publikováno v:
Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 46(10)
Background βIII-tubulin (TUBB3) is an isotype of microtubules, which are involved in crucial cellular roles including maintenance of cell shape, intracellular transport, and mitosis. Overexpression of TUBB3 was found to be associated with poor progn
Autor:
Alexander Knuth, Marcus Freytag, Giulio C. Spagnoli, Adrian Muenscher, Marco Blessmann, Gerd Ritter, Till S. Clauditz, Kerstin Borgmann, Waldemar Wilczak, Guido Sauter, Rainald Knecht, Tim Luetkens, Simon Laban, Djordje Atanackovic, Chia Jung Busch, Thomas K. Hoffmann
Publikováno v:
International Journal of Cancer. 135:1142-1152
The prognosis of head and neck squamous cell carcinoma (HNSCC) patients remains poor. The identification of high-risk subgroups is needed for the development of custom-tailored therapies. The expression of cancer-testis antigens (CTAs) has been linke
Autor:
Valerie, Zielinski, Simon, Laban, Silke, Tribius, Phillipe, Schafhausen, Simon, Veldhoen, Rainald, Knecht, Till, Clauditz, Adrian, Muenscher
Publikováno v:
Ear, nose,throat journal. 95(1)
Sinonasal undifferentiated carcinoma (SNUC) represents less than 1% of all malignancies. Most of the tumors are diagnosed at an advanced stage, when they have already invaded neighboring tissue structures. We describe the cases of 2 patients with a s
Publikováno v:
European Archives of Oto-Rhino-Laryngology. 270:831-840
The objective of this study was to investigate whether the labyrinthine structures of ancient Egyptian mummies differ significantly from modern labyrinths. The new technique of digital volume tomography (DVT) was used to visualize the temporal bones.
Publikováno v:
European Archives of Oto-Rhino-Laryngology. 270:505-510
Drilling during temporal bone surgery may result in temporary or permanent noise-induced hearing loss or tinnitus. This has practical implications for both the patient and the surgeon. Different surgical drill devices, routinely used in temporal bone