Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Adrian Mindel"'
Autor:
Wenkosi Perez Qulu, Gugulethu Mzobe, Andile Mtshali, Marothi Peter Letsoalo, Farzana Osman, James Emmanuel San, Asavela Olona Kama, Nigel Garrett, Adrian Mindel, Anne Rompalo, Lenine J. P. Liebenberg, Derseree Archary, Aida Sivro, Sinaye Ngcapu
Publikováno v:
Microorganisms, Vol 11, Iss 11, p 2643 (2023)
Metronidazole (MDZ) treatment failure and bacterial vaginosis (BV) recurrence rates are high among African women. This cohort study identified genital immune parameters associated with treatment response by comparing vaginal microbiota and immune cel
Externí odkaz:
https://doaj.org/article/69ffd93d87ca41f4a6a7c84294b7676a
Autor:
Wenkosi Qulu, Andile Mtshali, Farzana Osman, Nonsikelelo Ndlela, Lungelo Ntuli, Gugulethu Mzobe, Nivashnee Naicker, Nigel Garrett, Anne Rompalo, Adrian Mindel, Sinaye Ngcapu, Lenine Liebenberg
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294698 (2023)
IntroductionHuman papillomavirus (HPV) infection is a leading cause of cervical cancer. Although this relies on infection and persistence of HPV in epithelial cells, often occurring in the context of other sexually transmitted infections (STIs) and b
Externí odkaz:
https://doaj.org/article/b9b33dc368c24f92b2538ae46991afa0
Autor:
Andile Mtshali, James Emmanuel San, Farzana Osman, Nigel Garrett, Christina Balle, Jennifer Giandhari, Harris Onywera, Khanyisile Mngomezulu, Gugulethu Mzobe, Tulio de Oliveira, Anne Rompalo, Adrian Mindel, Salim S. Abdool Karim, Jacques Ravel, Jo-Ann S. Passmore, Quarraisha Abdool Karim, Heather B. Jaspan, Lenine J. P. Liebenberg, Sinaye Ngcapu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The standard treatment for bacterial vaginosis (BV) with oral metronidazole is often ineffective, and recurrence rates are high among African women. BV-associated anaerobes are closely associated with genital inflammation and HIV risk, which undersco
Externí odkaz:
https://doaj.org/article/98d16892801249a3b4f57f7f2494f3e7
Autor:
Khanyisile Mngomezulu, Gugulethu F. Mzobe, Andile Mtshali, Farzana Osman, Lenine J. P. Liebenberg, Nigel Garrett, Ravesh Singh, Anne Rompalo, Adrian Mindel, Salim S. Abdool Karim, Quarraisha Abdool Karim, Cheryl Baxter, Sinaye Ngcapu
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundThe presence of semen in the vagina from unprotected sex may influence the immune and microbial environment of the female genital tract. Inflammatory cytokine concentrations and BV-associated bacteria in female genital secretions may influe
Externí odkaz:
https://doaj.org/article/9f9a685a0da24e9399e8117d550dc24e
Autor:
Brian J. Morris, DSc, PhD, Catherine A. Hankins, MD, PhD, Eugenie R. Lumbers, MD, DSc, Adrian Mindel, MD, Jeffrey D. Klausner, MD, MPH, John N. Krieger, MD, Guy Cox, MA, DPhil
Publikováno v:
Sexual Medicine, Vol 7, Iss 2, Pp 145-161 (2019)
Introduction: Women’s choices for a sexual partner are influenced by numerous personal, cultural, social, political and religious factors, and may also include aspects of penile anatomy such as male circumcision (MC) status. Aim: To perform a syste
Externí odkaz:
https://doaj.org/article/8ff8d4e2c938401d802a374a5f3c5e2d
Autor:
Brian J. Morris, Catherine A. Hankins, Joya Banerjee, Eugenie R. Lumbers, Adrian Mindel, Jeffrey D. Klausner, John N. Krieger
Publikováno v:
Frontiers in Public Health, Vol 7 (2019)
Background: Male circumcision (MC) is proven to substantially reduce men's risk of a number of sexually transmitted infections (STIs). We conducted a detailed systematic review of the scientific literature to determine the relationship between MC and
Externí odkaz:
https://doaj.org/article/78c8cbb708914b279618e7ac9e1b3a6b
Autor:
Nigel J Garrett, Farzana Osman, Bhavna Maharaj, Nivashnee Naicker, Andrew Gibbs, Emily Norman, Natasha Samsunder, Hope Ngobese, Nireshni Mitchev, Ravesh Singh, Salim S Abdool Karim, Ayesha B M Kharsany, Koleka Mlisana, Anne Rompalo, Adrian Mindel
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0196209 (2018)
In light of the limited impact the syndromic management approach has had on the global sexually transmitted infection (STI) epidemic, we assessed a care model comprising point-of-care (POC) STI testing, immediate treatment, and expedited partner ther
Externí odkaz:
https://doaj.org/article/d15bffc9db3c4277b3ff4a4517baebfb
Autor:
Kwabena Asare, Tsion Andine, Nivashnee Naicker, Jienchi Dorward, Nishanta Singh, Elizabeth Spooner, Jessica Andriesen, Farzana Osman, Sinaye Ngcapu, Alain Vandormael, Adrian Mindel, Salim S Abdool Karim, Linda-Gail Bekker, Glenda Gray, Lawrence Corey, Andrew Tomita, Nigel Garrett
Publikováno v:
Clinical Infectious Diseases. 76:881-889
BackgroundAlternative approaches to syndromic management are needed to reduce rates of sexually transmitted infections (STIs) in resource-limited settings. We investigated the impact of point-of-care (POC) versus central laboratory–based testing on
Autor:
Kwabena Asare, Farzana Osman, Sinaye Ngcapu, Alain Vandormael, Nivashnee Naicker, Mlungisi Khanyile, Adrian Mindel, Salim S. Abdool Karim, Andrew Tomita, Nigel Garrett
Publikováno v:
Annals of epidemiology. 74
HIV and other sexually transmitted infections (STIs) often co-occur. However, less evidence exists on the long-term STI dynamics among persons living with HIV in sub-Saharan Africa to inform interventions. We investigated the incidence, prevalence an
Autor:
Jo-Ann S. Passmore, Anne Rompalo, Nigel Garrett, Ayesha B. M. Kharsany, Lindi Masson, Andile Mtshali, Ravesh Singh, Lenine J. P. Liebenberg, Salim S. Abdool Karim, Koleka Mlisana, Lyle R. McKinnon, Farzana Osman, Nireshni Mitchev, Hope Ngobese, Adrian Mindel
Publikováno v:
Sexually Transmitted Infections. 97:555-565
ObjectivesSTIs cause inflammation that is detrimental for both HIV risk and reproductive health. We assessed the impact of point-of-care (POC) STI testing, immediate treatment and expedited partner therapy (EPT) on genital tract cytokines among a coh