Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Adrian Maddaford"'
Autor:
David Leese, Donald Stuart Middleton, James Hart, Rebecca Glen, Xiurong Zhang, David C. Pryde, P. G. Wainwright, Neil Forrest, Thierry Guyot, Adrian Maddaford, Peter T. Stephenson
Publikováno v:
Tetrahedron Letters. 52:6415-6419
Robust practical routes to three different carbon-substituted nucleosides are described. Short synthetic procedures for preparing 1′-homonucleosides, 2′- C -methyl-carbanucleosides and 2′- C -methyl-cyclopropyl/cyclopentyl fused bicyclic ribose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dfb51baaca0e2ad162af42e99930c37
https://doi.org/10.1016/j.tetlet.2011.09.074
https://doi.org/10.1016/j.tetlet.2011.09.074
Autor:
Neil Forrest, Michael J. Simms, Adrian Maddaford, Rebecca Glen, Peter T. Stephenson, Xiurong Zhang, Sutton Scott Channing, David C. Pryde, Thierry Guyot, Donald Stuart Middleton, James Hart, P. G. Wainwright
Publikováno v:
Synlett. 2011:1900-1904
A novel systematic approach to the synthesis of 2-cyano-7-deaza-8-azapurinederived nucleosides is described. It is shown how this chemistrywas developed with the labile 2-substituted nitrile position inmind, and also how the same approach is applicab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21405d768f05b76512666bae5721365d
https://doi.org/10.1055/s-0030-1260943
https://doi.org/10.1055/s-0030-1260943
Autor:
Rebecca Glen, Adrian Maddaford, Cheryl L. Doherty, David Leese, Ray Fisher, James Hart, Xiurong Zhang, David C. Pryde, Thierry Guyot, Sutton Scott Channing, Donald Stuart Middleton, Nicholas Smith
Publikováno v:
Synlett. 2007:3149-3154
An efficient and flexible synthesis of 4-substituted ribose analogues is described. The key step involves the simple addition of a Grignard reagent to a ketone derived from a commercially available ribose. The addition of a range of Grignard reagents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e84c4d6abb3f86af64ba79c7690c16a2
https://doi.org/10.1055/s-2007-1000822
https://doi.org/10.1055/s-2007-1000822
Autor:
Rebecca Glen, Pei-Pei Kung, Sutton Scott Channing, Donald Stuart Middleton, Peter S. Stephenson, Javier González, Ray Fisher, David C. Pryde, Peter S. Dragovich, Adrian Maddaford, P. G. Wainwright
Publikováno v:
Synthesis. 2007:1378-1384
Synthesis of a RACEMIC 4′-ethynyl-2′-deoxyribose intermediate using stereoselective chelation control is presented. This intermediate is further transformed to 4′-ethynyl-2′-deoxy- and 4′-ethynyl-2′,3′-dideoxy-2′,3′-didehydronucleos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be5c6c7bf7538fa72871ac7461db2b47
https://doi.org/10.1055/s-2007-966009
https://doi.org/10.1055/s-2007-966009
Publikováno v:
Tetrahedron. 62:295-301
Two new atropisomeric 4-aminopyridine-based nucleophilic catalysts containing terphenyl 'blocking groups' have been prepared and evaluated for kinetic resolution (KR) of aryl alkyl sec-alcohols. One of these biaryls is shown to be the most selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d06ffcb9f3c9bbcbec94255431a64609
https://doi.org/10.1016/j.tet.2005.08.124
https://doi.org/10.1016/j.tet.2005.08.124
Autor:
Pei-Pei Kung, Sutton Scott Channing, Peter S. Dragovich, Andrew Lund, Adrian Maddaford, Donald Stuart Middleton, David Leese, Richard A. Bissell, Phillip Wainwright, Ray Fisher, Javier Gonzalez, David C. Pryde, Peter T. Stephenson, Karen Runcie
Publikováno v:
Synlett. :0765-0768
An efficient and flexible synthesis of cyclopentane and hydroxylated cyclopentane phosphonic acid analogues is described. The key step involves the opening of an epoxide with either a nucleoside base or a selenyl anion toaccess the target molecules.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be3c10f3c5d50fa0d9fd611f7c47b00c
https://doi.org/10.1055/s-2005-863745
https://doi.org/10.1055/s-2005-863745
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1785-1794
The regioselectivity of α-metalation–methylation of N-BF3 adducts of 4-(dimethylamino)pyridines as a function of β-substitution is examined in attempts to prepare configurationally stable atropisomeric derivatives (I and II) having an α-methyl s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d7afcafcce0326cd9d6c2c73dae706a
https://doi.org/10.1039/b103385a
https://doi.org/10.1039/b103385a
Publikováno v:
Organic Preparations and Procedures International. 32:331-365
(2000). ASYMMETRIC CATALYSIS OF ACYL TRANSFER BY LEWIS ACIDS AND NUCLEOPHILES. A REVIEW. Organic Preparations and Procedures International: Vol. 32, No. 4, pp. 331-365.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2c5dca40768b1b78add4b5a806aac47
https://doi.org/10.1080/00304940009355935
https://doi.org/10.1080/00304940009355935
Autor:
Tomasz Fekner, Adrian Maddaford, Alan C. Spivey, Alison Judith Redgrave, Christopher S. Frampton
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :3460-3468
The syntheses of a series of enantiomerically pure C2-symmetric 4-(pyrrolidino)pyridine (PPY) derivatives by SNAr of 4-halo-/4-phenoxypyridines and by cyclocondensation from 4-aminopyridine are described. Preliminary results pertaining to their use a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::266fb6add393c8c4f754d52b4fb07060
https://doi.org/10.1039/b004704j
https://doi.org/10.1039/b004704j
Autor:
Adrian Maddaford, Alan C. Spivey
Publikováno v:
Annual Reports Section "B" (Organic Chemistry). 95:83-95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c19622d5ad652fc3baa9e66abb56aeb
https://doi.org/10.1039/a808598f
https://doi.org/10.1039/a808598f